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Gene Expression Data
Assay Details
Assay
Reference: J:18126 Holdener BC, et al., msd is required for mesoderm induction in mice. Development. 1994 May;120(5):1335-46
Assay type: RNA in situ
MGI Accession ID: MGI:1338424
Gene symbol: Fgfr2
Gene name: fibroblast growth factor receptor 2
Probe: Bek probe
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen Table 1 mutant: embryonic day 7.5; Tyrc-1DThWb/Tyrc-1DThWb (more )
Structure Level Pattern Image Note
TS11: chorion ectoderm Present
TS11: ectoplacental cone Absent
TS11: embryo ectoderm Absent
TS11: extraembryonic visceral endoderm Absent
TS11: parietal endoderm Absent
TS11: primitive streak Absent
Specimen Table 1 wild type: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: chorion ectoderm Present
TS11: ectoplacental cone Absent
TS11: embryo ectoderm Absent
TS11: extraembryonic visceral endoderm Absent
TS11: parietal endoderm Absent
TS11: primitive streak Absent
Specimen 4A/B: embryonic day 7.5 (more )
Note: Parasagittal section
Structure Level Pattern Image Note
TS11: chorion ectoderm Present 4A/B
Specimen 4C/D: embryonic day 8.5 (more )
Note: Sagittal section near the midline
Structure Level Pattern Image Note
TS13: extraembryonic component Weak Regionally restricted 4C/D Expression is down-regulated in the chorionic ectoderm.
TS13: head somite Present 4C/D
TS13: heart Present 4C/D
TS13: neural ectoderm Present 4C/D
TS13: surface ectoderm Present 4C/D
Specimen 4E/F: embryonic day 8.5; Tyrc-1DThWb/Tyrc-1DThWb (more )
Note: Sagittal section
Structure Level Pattern Image Note
TS13: extraembryonic component Present Regionally restricted 4E/F Expression in the mutant embryo is similar to that of 7.5dpc wild-type embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/30/2025
MGI 6.24 		The Jackson Laboratory