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Gene Expression Data
Assay Details
Assay
Reference: J:29276 Acampora D, et al., Forebrain and midbrain regions are deleted in Otx2-/- mutants due to a defective anterior neuroectoderm specification during gastrulation. Development. 1995 Oct;121(10):3279-90
Assay type: RNA in situ
MGI Accession ID: MGI:1337935
Gene symbol: Emx2
Gene name: empty spiracles homeobox 2
Probe: Emx2 cDNA
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 4a,b: embryonic day 9.5; Otx2tm1Pas/Otx2tm1Pas (more )
Note: This is a sagittal section of an embryo with a mild phenotype.
Structure Level Pattern Image Note
TS15: embryo Absent 4a/b No expression is seen in the head region of these mutant embryos. Posterior expression was seen in an embryo with a weak phenotype.

Specimen not shown: embryonic day 9.0; Otx2tm1Pas/Otx2tm1Pas (more )
Structure Level Pattern Image Note
TS14: olfactory placode Absent This structure is missing in mutant embryos.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory