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Gene Expression Data
Assay Details
Assay
Reference: J:15300 Nieto MA, et al., A receptor protein tyrosine kinase implicated in the segmental patterning of the hindbrain and mesoderm. Development. 1992 Dec;116(4):1137-50
Assay type: RNA in situ
MGI Accession ID: MGI:1336972
Gene symbol: Epha4
Gene name: Eph receptor A4
Probe: probe 2
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 5.B: embryonic day 7.75 (more )
Note: 0-somite stage.
Structure Level Pattern Image Note
TS11: future brain Present 5A/B Expression is present in the future hindbrain.
Specimen 5.D: embryonic day 8.0 (more )
Note: 2-somite stage.
Structure Level Pattern Image Note
TS12: future spinal cord neural plate Present Regionally restricted 5C/D Expression is detected in the anterior neural plate.
Specimen 5.F: embryonic day 8.0 (more )
Note: 4-somite stage.
Structure Level Pattern Image Note
TS12: future spinal cord neural plate Present Regionally restricted 5E/F Expression is detected in the anterior neural plate.
Specimen 5.H: embryonic day 8.0 (more )
Note: 6-somite stage.
Structure Level Pattern Image Note
TS12: future spinal cord neural plate Present Regionally restricted 5G/H Expression is detected in the anterior neural plate.
Specimen 5.J: embryonic day 8.5 (more )
Note: 8-somite stage.
Structure Level Pattern Image Note
TS12: future spinal cord neural plate Present Regionally restricted 5I/J
Specimen 5.M: embryonic day 9.0 (more )
Note: 20-somite stage.
Structure Level Pattern Image Note
TS15: telencephalon Present Regionally restricted 5L/M
TS15: diencephalon Present Regionally restricted 5L/M Expression is detected in the dorsal diencephalon, but not the ventral diencephalon.
Specimen 5.O: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: telencephalon Present Regionally restricted 5N/O Expression is restricted to the cortical neuroepithelium and the basal telencephalon.
Specimen 6.B: embryonic day 8.5 (more )
Note: 12-somite stage.
Structure Level Pattern Image Note
TS13: future spinal cord Absent 6A/B
Specimen 6.D: embryonic day 9.5 (more )
Note: 25-somite stage.
Structure Level Pattern Image Note
TS15: future spinal cord Weak Regionally restricted 6C/D Low levels of expression are detected in the ventral part of the rostral spinal cord.
Specimen 6.F: embryonic day 9.5 (more )
Note: 25-somite stage.
Structure Level Pattern Image Note
TS15: future spinal cord Weak Regionally restricted 6E/F No expression is detected in the caudal spinal cord at this age.
Specimen 6.H: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted 6G/H Expression is detected in the rostral spinal cord in a widespread pattern, with higher levels in ventral and dorsolateral regions.
Specimen 6.J: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted 6I/J Expression in the caudal spinal cord is restricted to ventral part.
Specimen 6.L: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spinal cord Present Regionally restricted 6K/L Expression in rostral spinal cord is restricted to the ventral motor horns and the ventral part of the proliferating ependymal layer.
Specimen not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spinal cord Present Regionally restricted Expression is widespread in caudal spinal cord.
Specimen 7.B: embryonic day 8.0 (more )
Note: 3-somite stage.
Structure Level Pattern Image Note
TS12: trunk unsegmented mesenchyme Present Regionally restricted 7A/B
Specimen 7.D: embryonic day 9.0 (more )
Note: 20-somite stage.
Structure Level Pattern Image Note
TS14: trunk unsegmented mesenchyme Present Regionally restricted 7C/D
Specimen 7.F: embryonic day 9.5 (more )
Note: ~25-somite stage.
Structure Level Pattern Image Note
TS15: tail unsegmented mesenchyme Present Regionally restricted 7E/F
Specimen 8.B: embryonic day 9.5 (more )
Note: 25-somite stage.
Structure Level Pattern Image Note
TS14: head mesenchyme derived from neural crest Present Regionally restricted 8A/B Expression is detected in the neural crest adjacent to rhombomere 6, but not in more rostral regions.
TS14: thyroid primordium Present 8A/B
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory