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Gene Expression Data
Assay Details
Assay
Reference: J:52212 Lu MF, et al., Paired-related homeobox genes cooperate in handplate and hindlimb zeugopod morphogenesis. Dev Biol. 1999 Jan 1;205(1):145-57
Assay type: RNA in situ
MGI Accession ID: MGI:1336733
Gene symbol: Fgf8
Gene name: fibroblast growth factor 8
Results
Specimen 4A: embryonic day 10.5; Prrx2tm1Mjk/Prrx2tm1Mjk (more )
Note: lateral view
Structure Level Pattern Image Note
TS17: forelimb bud apical ectodermal ridge Strong 4A
Specimen 4C: embryonic day 10.5; Prrx2tm1Mjk/Prrx2tm1Mjk (more )
Note: edge-on view
Structure Level Pattern Image Note
TS17: forelimb bud apical ectodermal ridge Strong 4C
Specimen 4B: embryonic day 10.5; Prrx1tm1Tex/Prrx1tm1Tex, Prrx2tm1Mjk/Prrx2tm1Mjk (more )
Note: lateral view
Structure Level Pattern Image Note
TS17: forelimb bud apical ectodermal ridge Strong Regionally restricted 4B Expression is abnormally truncated at the posterior aspect of the 10.5-dpc forelimb bud. The degree of AER truncation varied between embryos, and even between left and right forelimbs in a single embryo.
Specimen not shown: embryonic day 10.5; Prrx1tm1Tex/Prrx1tm1Tex, Prrx2tm1Mjk/Prrx2tm1Mjk (more )
Structure Level Pattern Image Note
TS17: apical ectodermal ridge Present Expression in the mutant is the same as in wild type embryos.
Specimen 4D: embryonic day 10.5; Prrx1tm1Tex/Prrx1tm1Tex, Prrx2tm1Mjk/Prrx2tm1Mjk (more )
Note: edge-on view
Structure Level Pattern Image Note
TS17: forelimb bud apical ectodermal ridge Strong Regionally restricted 4D Expression is abnormally truncated at the posterior aspect of the 10.5-dpc forelimb bud. The degree of AER truncation varied between embryos, and even between left and right forelimbs in a single embryo.
Specimen not shown: embryonic day 10.5; Prrx1tm1Tex/Prrx1tm1Tex, Prrx2tm1Mjk/Prrx2tm1Mjk (more )
Structure Level Pattern Image Note
TS17: apical ectodermal ridge Present Expression in the mutant is the same as in wild type embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/28/2026
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