Gene Expression Data
Assay Details
Assay
|
Reference:
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J:30825
Sporle R, et al., Severe defects in the formation of epaxial musculature in open brain (opb) mutant mouse embryos. Development. 1996 Jan;122(1):79-86
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:1336671
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Gene symbol:
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Myog
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Gene name:
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myogenin
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Results
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Specimen
not shown:
embryonic day 12.5
(more )
Specimen
not shown:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 12.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
Not Specified
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Fixation:
|
4% Paraformaldehyde
|
Specimen
3A:
embryonic day 11.5
(more )
Note: 3A is at the upper thoracic level.
Specimen
3A:
(close )
Genetic Background:
|
C57BL/6
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Age:
|
embryonic day 11.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
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Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Note:
|
3A is at the upper thoracic level.
|
Specimen
3B:
embryonic day 11.5; Rab23opb/ Rab23opb
(more )
Note: 3B is at the upper thoracic level.
Specimen
3B:
(close )
Genetic Background:
|
involves: C57BL/6 * NMRI
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Mutant Allele(s):
|
Rab23opb/Rab23opb
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Age:
|
embryonic day 11.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Note:
|
3B is at the upper thoracic level.
|
Structure |
Level |
Pattern |
Image |
Note |
TS19: body wall mesenchyme |
Present |
Regionally restricted |
3B
|
Expression in lower cervical and upper thoracic regions of mutants shows a severe reduction in formation of dorsal muscle, but formation of ventral musculature and intercostal muscle was not impaired.
|
Specimen
3C:
embryonic day 11.5
(more )
Note: 3C is at the lower thoracic level.
Specimen
3C:
(close )
Genetic Background:
|
C57BL/6
|
Age:
|
embryonic day 11.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Note:
|
3C is at the lower thoracic level.
|
Specimen
3D:
embryonic day 11.5; Rab23opb/ Rab23opb
(more )
Note: 3D is at the lower thoracic level.
Specimen
3D:
(close )
Genetic Background:
|
involves: C57BL/6 * NMRI
|
Mutant Allele(s):
|
Rab23opb/Rab23opb
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Age:
|
embryonic day 11.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Note:
|
3D is at the lower thoracic level.
|
Structure |
Level |
Pattern |
Image |
Note |
TS19: body wall mesenchyme |
Present |
Regionally restricted |
3D
|
Expression in lower thoracic regions of mutants shows almost no dorsal musculature, but formation of ventral musculature and intercostal muscle was not impaired.
|
Specimen
3E:
embryonic day 11.5
(more )
Note: 3E is at the lumbar/hindlimb level.
Specimen
3E:
(close )
Genetic Background:
|
C57BL/6
|
Age:
|
embryonic day 11.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Note:
|
3E is at the lumbar/hindlimb level.
|
Specimen
3F:
embryonic day 11.5; Rab23opb/ Rab23opb
(more )
Note: 3F is at the lumbar/hindlimb level.
Specimen
3F:
(close )
Genetic Background:
|
involves: C57BL/6 * NMRI
|
Mutant Allele(s):
|
Rab23opb/Rab23opb
|
Age:
|
embryonic day 11.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Note:
|
3F is at the lumbar/hindlimb level.
|
Structure |
Level |
Pattern |
Image |
Note |
TS19: hindlimb bud mesenchyme |
Present |
Regionally restricted |
3F
|
Expression shows formation of limb muscle was not impaired.
|
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