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Gene Expression Data
Assay Details
Assay
Reference: J:41027 Zhong W, et al., Differential expression of mammalian Numb, Numblike and Notch1 suggests distinct roles during mouse cortical neurogenesis. Development. 1997 May;124(10):1887-97
Assay type: Immunohistochemistry
MGI Accession ID: MGI:1335645
Gene symbol: Numbl
Gene name: numb-like
Antibody: anti-MNBL1
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to fluorescein
Assay notes: Nbl expression patterns are recognized by comparing the staining pattern of anti-MNBL1 (MGI:1335643), which recognizes both Nbl and m-Numb, to the staining pattern of anti-MNBR1 (MGI:1335644), which specifically recognizes m-Numb.
Results
Specimen 6K: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spinal cord mantle layer Present 6K In the caudal spinal cord, where active neurogenesis was still underway, expression was limited to the mantle zone, including the differentiating motor neurons of the ventral horn.
Specimen 7A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cortical plate Present 7A
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory