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Gene Expression Data
Assay Details
Assay
Reference: J:38385 Conway SJ, et al., Pax3 is required for cardiac neural crest migration in the mouse: evidence from the splotch (Sp2H) mutant. Development. 1997 Jan;124(2):505-14
Assay type: RNA in situ
MGI Accession ID: MGI:1335055
Gene symbol: Prrx1
Gene name: paired related homeobox 1
Probe: Prx1 probe5
Probe preparation: Antisense RNA
Results
Specimen 10A/B: embryonic day 10.5 (more )
Note: Control embryo was either Sp2H/+ or +/+.
Structure Level Pattern Image Note
TS17: 3rd branchial arch Present Regionally restricted 10A , 10B Prx1 was expressed in a stream of cells that appeared to transverse the third, fourth and developing sixth branchial arches, entering the aortic sac and outflow tract in a similar fashion to Pax3.
TS17: 4th branchial arch Present Regionally restricted 10A , 10B Prx1 was expressed in a stream of cells that appeared to transverse the third, fourth and developing sixth branchial arches, entering the aortic sac and outflow tract in a similar fashion to Pax3.
TS17: 6th branchial arch Present Regionally restricted 10A , 10B Prx1 was expressed in a stream of cells that appeared to transverse the third, fourth and developing sixth branchial arches, entering the aortic sac and outflow tract in a similar fashion to Pax3.
TS17: outflow tract Present Regionally restricted 10A , 10B Prx1 was expressed in a stream of cells that appeared to transverse the third, fourth and developing sixth branchial arches, entering the aortic sac and outflow tract in a similar fashion to Pax3.
TS17: 1st branchial arch Present 10A , 10B
TS17: 1st branchial arch maxillary component Present 10A , 10B
TS17: 2nd branchial arch Present 10A , 10B
TS17: limb Present 10B , 10A Prx1 was present in the limb bud.
TS17: neural tube Absent 10B , 10A
TS17: trunk somite Absent 10A , 10B Somite derivatives were negative.

Specimen 10C/D: embryonic day 10.5; Pax3Sp-2H/Pax3Sp-2H (more )
Structure Level Pattern Image Note
TS17: 3rd branchial arch Weak Regionally restricted 10C , 10D The stream of cells expressing Prx1 was considerably reduced in mutant embryos.
TS17: 4th branchial arch Weak Regionally restricted 10C , 10D The stream of cells expressing Prx1 was considerably reduced in mutant embryos.
TS17: 6th branchial arch Weak Regionally restricted 10C , 10D The stream of cells expressing Prx1 was considerably reduced in mutant embryos.
TS17: outflow tract Weak Regionally restricted 10C , 10D The stream of cells expressing Prx1 was considerably reduced in mutant embryos.
TS17: 1st branchial arch Present 10D , 10C Expression in this mutant is the same as in wild-type embryos.
TS17: 1st branchial arch maxillary component Present 10D , 10C Expression in this mutant is the same as in wild-type embryos.
TS17: 2nd branchial arch Present 10D , 10C Expression in this mutant is the same as in wild-type embryos.
TS17: limb Present 10D , 10C Expression in this mutant is the same as in wild-type embryos.
TS17: neural tube Absent 10D , 10C Expression in this mutant is the same as in wild-type embryos.
TS17: trunk somite Absent 10D , 10C Expression in this mutant is the same as in wild-type embryos.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory