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Gene Expression Data
Assay Details
Assay
Reference: J:38385 Conway SJ, et al., Pax3 is required for cardiac neural crest migration in the mouse: evidence from the splotch (Sp2H) mutant. Development. 1997 Jan;124(2):505-14
Assay type: RNA in situ
MGI Accession ID: MGI:1335053
Gene symbol: Crabp1
Gene name: cellular retinoic acid binding protein I
Probe: Crabp-1 cDNA1
Probe preparation: Antisense RNA
Results
Specimen 9C: embryonic day 10.5 (more )
Note: Control embryo was either Sp2H/+ or +/+.
Structure Level Pattern Image Note
TS17: 3rd branchial arch Present Regionally restricted 9C Crabp1 was expressed in a stream of cells that appeared to transverse the third, fourth and developing sixth branchial arches, entering the aortic sac and outflow tract in a similar fasion to Pax3.
TS17: 4th branchial arch Present Regionally restricted 9C Crabp1 was expressed in a stream of cells that appeared to transverse the third, fourth and developing sixth branchial arches, entering the aortic sac and outflow tract in a similar fasion to Pax3.
TS17: 6th branchial arch Present Regionally restricted 9C Crabp1 was expressed in a stream of cells that appeared to transverse the third, fourth and developing sixth branchial arches, entering the aortic sac and outflow tract in a similar fasion to Pax3.
TS17: outflow tract Present Regionally restricted 9C Crabp1 was expressed in a stream of cells that appeared to transverse the third, fourth and developing sixth branchial arches, entering the aortic sac and outflow tract in a similar fasion to Pax3.
TS17: 1st branchial arch Present 9C
TS17: fronto-nasal process Present 9C
TS17: neural tube Present 9C
TS17: limb Present 9C Expression was seen in the limb bud.

Specimen 9D: embryonic day 10.5; Pax3Sp-2H/Pax3Sp-2H (more )
Structure Level Pattern Image Note
TS17: 3rd branchial arch Absent 9D The stream of cells expressing Crabp1 was absent in mutant embryos.
TS17: 4th branchial arch Absent 9D The stream of cells expressing Crabp1 was absent in mutant embryos.
TS17: 6th branchial arch Absent 9D The stream of cells expressing Crabp1 was absent in mutant embryos.
TS17: outflow tract Absent 9D The stream of cells expressing Crabp1 was absent in mutant embryos.
TS17: fronto-nasal process Present 9D Expression in this mutant is the same as in wild-type embryos.
TS17: limb Present 9D Expression in this mutant is the same as in wild-type embryos.
TS17: neural tube Present 9D Expression in this mutant is the same as in wild-type embryos.
TS17: 1st branchial arch Absent 9D


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory