Gene Expression Data
Assay Details
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Assay
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Reference:
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J:45779
Jernvall J, et al., The life history of an embryonic signaling center: BMP-4 induces p21 and is associated with apoptosis in the mouse tooth enamel knot. Development. 1998 Jan;125(2):161-9
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:1332291
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Gene symbol:
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Msx2
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Gene name:
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msh homeobox 2
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Probe:
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Msx2 probe
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Probe preparation:
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labelled with digoxigenin RNA
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Visualized with:
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Alkaline phosphatase
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Results
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Specimen
1 left:
embryonic day 13.0
(more  )
Note: Bud stage; initiation.
Specimen
1 left:
(close  )
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Genetic Background:
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(CBA x NMRI)F1
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Age:
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embryonic day 13.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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Bud stage; initiation.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: enamel knot |
Present |
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1_Msx-2 left
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Expression extends beyond the enamel knot in the dental epithelium, facing the expression domain of BMP-4 in the mesenchyme.
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| TS21: lower jaw molar epithelium |
Present |
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1_Msx-2 left
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Expression extends beyond the enamel knot in the dental epithelium, facing the expression domain of BMP-4 in the mesenchyme.
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Specimen
2 right:
embryonic day 14.0
(more )
Note: Cap stage; fully formed.
Specimen
2 right:
(close )
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Genetic Background:
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(CBA x NMRI)F1
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Age:
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embryonic day 14.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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Cap stage; fully formed.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: enamel knot |
Present |
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1_Msx-2 right
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Expression extends beyond the enamel knot in the dental epithelium, facing the expression domain of BMP-4 in the mesenchyme.
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| TS22: lower jaw molar epithelium |
Present |
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1_Msx-2 right
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Expression extends beyond the enamel knot in the dental epithelium, facing the expression domain of BMP-4 in the mesenchyme.
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Specimen
not shown:
embryonic day 14.5-15.0
(more )
Note: Late cap stage.
Specimen
not shown:
(close )
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Genetic Background:
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(CBA x NMRI)F1
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Age:
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embryonic day 14.5-15.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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Late cap stage.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: enamel knot |
Present |
Regionally restricted |
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The distal part of the knot has disappeared and no transcripts are present in this area. The remaining half (mesial) of the enamel knot continues to express.
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| TS22: lower jaw molar enamel organ |
Present |
Regionally restricted |
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The distal part of the knot has disappeared and no transcripts are present in this area. The remaining half (mesial) of the enamel knot continues to express.
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Analysis Tools