Gene Expression Data
Assay Details
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Assay
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Reference:
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J:50582
Roebroek AJ, et al., Failure of ventral closure and axial rotation in embryos lacking the proprotein convertase Furin. Development. 1998 Dec;125(24):4863-76
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:1329808
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Gene symbol:
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Furin
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Gene name:
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furin, paired basic amino acid cleaving enzyme
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Probe:
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Pcsk3 probe2
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
1A:
embryonic day 7.5
(more  )
Note: Dashed lines indicate the level of sectioning in B and C, respectively.
Specimen
1A:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 7.5
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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Dashed lines indicate the level of sectioning in B and C, respectively.
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Specimen
1B:
embryonic day 7.5
(more )
Note: A transverse section through the extraembryonic region is shown.
Specimen
1B:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 7.5
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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A transverse section through the extraembryonic region is shown.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS11: extraembryonic component |
Present |
Regionally restricted |
1B
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Expression is localized to the mesoderm and primitive endoderm. No expression is seen in the most proximal primitive endoderm contacting the extraembryonic ectoderm.
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Specimen
1C:
embryonic day 7.5
(more )
Note: A transverse section through the embryonic region is shown.
Specimen
1C:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 7.5
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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A transverse section through the embryonic region is shown.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS11: anterior visceral endoderm |
Strong |
Regionally restricted |
1C
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Expression is restricted to the most anterior visceral endoderm.
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| TS11: heart |
Strong |
Regionally restricted |
1C
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Expression is seen in the precardiac mesoderm.
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| TS11: embryo |
Strong |
Regionally restricted |
1C
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Authors describe expression in ectodermal cells in antero-proximal region of the epiblast.
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Specimen
1D:
embryonic day 8.0
(more )
Specimen
1D:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 8.0
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Age Note:
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Theiler stage of this specimen assigned by curators from EMAGE.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS11: allantois |
Strong |
Uniform |
1D
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| TS11: embryo |
Strong |
Regionally restricted |
1D
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Strong expression is seen in the anterior intestinal portal within mesodermal and endodermal cells subjacent to the headfolds.
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Specimen
1E:
embryonic day 8.0
(more )
Specimen
1E:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 8.0
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Age Note:
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Theiler stage of this specimen assigned by curators from EMAGE.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS11: notochordal plate |
Strong |
Regionally restricted |
1E
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Strong expression is seen in the periphery of the ventral notochordal plate.
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Specimen
1F:
embryonic day 8.5
(more )
Specimen
1F:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 8.5
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Age Note:
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Theiler stage of this specimen assigned by curators from EMAGE.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS12: extraembryonic component |
Present |
Regionally restricted |
1F
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High expression levels are seen in the allantois.
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| TS12: heart |
Strong |
Graded |
1F
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Strong expression is seen in the primordial heart, with particularly high levels in the inflow tract and anterior intestinal portal.
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Specimen
1G:
embryonic day 8.5
(more )
Specimen
1G:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 8.5
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Age Note:
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Theiler stage of this specimen assigned by curators from EMAGE.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS12: gut |
Present |
Regionally restricted |
1G
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Expression is seen throughout the foregut endoderm.
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Specimen
1H:
embryonic day 8.5
(more )
Specimen
1H:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 8.5
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Age Note:
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Theiler stage of this specimen assigned by curators from EMAGE.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS12: gut |
Present |
Regionally restricted |
1H
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Expression is seen throughout the foregut endoderm.
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Specimen
1I:
embryonic day 8.5
(more )
Specimen
1I:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 8.5
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Age Note:
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Theiler stage of this specimen assigned by curators from EMAGE.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS12: trunk mesenchyme |
Present |
Regionally restricted |
1I
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Expression is seen in lateral plate mesoderm of trunk.
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Specimen
1J:
embryonic day 8.5
(more )
Specimen
1J:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 8.5
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Age Note:
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Theiler stage of this specimen assigned by curators from EMAGE.
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
1K:
embryonic day 8.5
(more )
Specimen
1K:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 8.5
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Age Note:
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Theiler stage of this specimen assigned by curators from EMAGE.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS12: gut |
Present |
Regionally restricted |
1K
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Expression is seen in the hindgut and caudal intestinal portal.
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