Gene Expression Data
Assay Details
Assay
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Reference:
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J:49252
Hardcastle Z, et al., The Shh signalling pathway in tooth development: defects in Gli2 and Gli3 mutants. Development. 1998 Aug;125(15):2803-11
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:1320904
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Gene symbol:
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Gli3
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Gene name:
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GLI-Kruppel family member GLI3
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Probe:
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Gli3 probe2
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Probe preparation:
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Antisense labelled with S35 RNA
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Results
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Specimen
1F:
embryonic day 11.5
(more )
Specimen
1F:
(close )
Genetic Background:
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CD-1
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Specimen
1L:
embryonic day 12.5
(more )
Note: Early tooth bud stage.
Specimen
1L:
(close )
Genetic Background:
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CD-1
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Note:
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Early tooth bud stage.
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Structure |
Level |
Pattern |
Image |
Note |
TS20: mandibular process |
Present |
Regionally restricted |
1L
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Gli3 was significantly more localized in the mesenchyme around the tooth germs than at previous stages of development.
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TS20: maxillary process |
Present |
Regionally restricted |
1L
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Gli3 was significantly more localized in the mesenchyme around the tooth germs than at previous stages of development.
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Specimen
1R:
embryonic day 13.5
(more )
Specimen
1R:
(close )
Genetic Background:
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CD-1
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Age:
|
embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS21: lower jaw incisor |
Strong |
Regionally restricted |
1R
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In the molars and mandibular incisors, Gli3 was expressed uniformly in the mesenchyme surrounding the dental organ.
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TS21: lower jaw molar |
Strong |
Regionally restricted |
1R
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In the molars and mandibular incisors, Gli3 was expressed uniformly in the mesenchyme surrounding the dental organ.
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TS21: upper jaw molar |
Strong |
Regionally restricted |
1R
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In the molars and mandibular incisors, Gli3 was expressed uniformly in the mesenchyme surrounding the dental organ.
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TS21: upper jaw incisor |
Strong |
Regionally restricted |
1R
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In the maxillary incisors, the mesenchymal expression was greater on the buccal side of the tooth germ.
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Specimen
1X:
embryonic day 14.5
(more )
Note: Cap stage.
Specimen
1X:
(close )
Genetic Background:
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CD-1
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Note:
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Cap stage.
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