Gene Expression Data
Assay Details
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Assay
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Reference:
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J:49252
Hardcastle Z, et al., The Shh signalling pathway in tooth development: defects in Gli2 and Gli3 mutants. Development. 1998 Aug;125(15):2803-11
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:1320903
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Gene symbol:
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Gli2
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Gene name:
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GLI-Kruppel family member GLI2
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Probe:
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Gli2 probe1
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Probe preparation:
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Antisense labelled with S35 RNA
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Results
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Specimen
1E:
embryonic day 11.5
(more  )
Specimen
1E:
(close  )
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Genetic Background:
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CD-1
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Specimen
1K:
embryonic day 12.5
(more )
Note: Early tooth bud stage.
Specimen
1K:
(close )
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Genetic Background:
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CD-1
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Note:
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Early tooth bud stage.
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Specimen
1Q:
embryonic day 13.5
(more )
Specimen
1Q:
(close )
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Genetic Background:
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CD-1
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: molar epithelium |
Present |
Regionally restricted |
1Q
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Gli2 transcripts in the molars and maxillary incisors were now more localized around the tooth germs and were still detected in both the epithelial and mesenchymal components of the developing teeth.
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| TS21: molar mesenchyme |
Present |
Regionally restricted |
1Q
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Gli2 transcripts in the molars and maxillary incisors were now more localized around the tooth germs and were still detected in both the epithelial and mesenchymal components of the developing teeth.
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| TS21: upper jaw incisor epithelium |
Present |
Regionally restricted |
1Q
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Gli2 transcripts in the molars and maxillary incisors were now more localized around the tooth germs and were still detected in both the epithelial and mesenchymal components of the developing teeth.
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| TS21: upper jaw incisor mesenchyme |
Present |
Regionally restricted |
1Q
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Gli2 transcripts in the molars and maxillary incisors were now more localized around the tooth germs and were still detected in both the epithelial and mesenchymal components of the developing teeth.
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| TS21: upper jaw incisor |
Present |
Regionally restricted |
1Q
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Gli2 transcripts in the maxillary incisors were observed to be more strongly expressed medial to the tooth germs.
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| TS21: lower jaw incisor |
Present |
Uniform |
1Q
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Gli2 continued to be expressed uniformly around the mandibular incisors.
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Specimen
1W:
embryonic day 14.5
(more )
Note: Cap stage.
Specimen
1W:
(close )
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Genetic Background:
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CD-1
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Note:
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Cap stage.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: dental sac |
Present |
Regionally restricted |
1W
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Expression in the dental follicle surrounding the dental organ and dental papilla
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| TS22: molar |
Present |
Regionally restricted |
1W
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Expression in the dental follicle surrounding the dental organ and dental papilla
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| TS22: molar epithelium |
Weak |
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1W
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| TS22: enamel knot |
Absent |
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1C'
,
1W
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No expression in the molar enamel knot.
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Specimen
not shown:
embryonic day 14.5
(more )
Note: Cap stage.
Specimen
not shown:
(close )
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Genetic Background:
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CD-1
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Note:
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Cap stage.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: maxilla |
Weak |
Regionally restricted |
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Weak expression in the maxilla at the site of fusion between the nasal septum and the primary palate.
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| TS22: incisor mesenchyme |
Weak |
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Analysis Tools