About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:46975 Ericson J, et al., Integrated FGF and BMP signaling controls the progression of progenitor cell differentiation and the emergence of pattern in the embryonic anterior pituitary. Development. 1998 Mar;125(6):1005-15
Assay type: Immunohistochemistry
MGI Accession ID: MGI:1316702
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Results
Specimen e8.5: embryonic day 8.5 (more )
Note: 10 somite stage.
Structure Level Pattern Image Note
TS13: oral region Present 1B Expression of Isl1 is detected in oral roof ectoderm cells that underlie the ventral diencephalon and give rise to Rathke's pouch.

Specimen e9.5: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: Rathke's pouch Present Uniform 1H

Specimen e10.5: embryonic day 10.5-11.0 (more )
Structure Level Pattern Image Note
TS17: Rathke's pouch Present Regionally restricted 1N Isl1 expression is gradually extinguished from Rathke's pouch cells located closest to the infundibulum.

Specimen e11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: Rathke's pouch Present Regionally restricted 1T The expression of Isl1 persists in cells in the ventral domain of Rathke's pouch.

Specimen e12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: adenohypophysis Present Regionally restricted 1Z Isl1 expression is in the ventral region of the anterior pituitary.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory