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Gene Expression Data
Assay Details
Assay
Reference: J:46379 Wang W, et al., Inner ear and maternal reproductive defects in mice lacking the Hmx3 homeobox gene. Development. 1998 Feb;125(4):621-34
Assay type: RNA in situ
MGI Accession ID: MGI:1310073
Gene symbol: Wnt5a
Gene name: wingless-type MMTV integration site family, member 5A
Probe: p59
Probe preparation: Antisense labelled with S35 RNA
Results
Specimen 7 unpregnant +/+: postnatal adult (more )
Structure Level Pattern Image Note
TS28: uterus Present Regionally restricted 7_Wnt5A unpregnant +/+ Wnt5A is expressed in the uterine stroma and very weakly in the endometrial epithelium.
Specimen 7 unpregnant -/-: postnatal adult; Hmx3tm2Tlu/Hmx3tm2Tlu (more )
Note: It is unclear whether the null mice are carrying the neo or the lacZ allele. The assays have been annotated using the lacZ allele but the neo allele could have been used instead.
Structure Level Pattern Image Note
TS28: uterus Present Regionally restricted 7_Wnt5A unpregnant -/- Wnt5A expression is dramatically altered, and is strongly expressed in the endometrial eithelium and at normal levels in the stroma.
Specimen 7 pregnant +/+: postnatal adult (more )
Structure Level Pattern Image Note
TS28: uterus Present Regionally restricted 7_Wnt5A pregnant +/+ Wnt5A expression is most pronounced in the glandular epithelium embedded in the stroma and in the endometrial epithelium.
Specimen 7 pregnant -/-: postnatal adult; Hmx3tm2Tlu/Hmx3tm2Tlu (more )
Note: It is unclear whether the null mice are carrying the neo or the lacZ allele. The assays have been annotated using the lacZ allele but the neo allele could have been used instead.
Structure Level Pattern Image Note
TS28: uterus Present Regionally restricted 7_Wnt5A pregnant -/- Wnt5A showed a dramatic increase in expression throughout the uterine stroma, with expression increasing in stromal cells located with increasing proximity to the myometrial layer. No elevated expression was observed within the endometrial epithelium.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory