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Gene Expression Data
Assay Details
Assay
Reference: J:46371 Lo L, et al., MASH1 activates expression of the paired homeodomain transcription factor Phox2a, and couples pan-neuronal and subtype-specific components of autonomic neuronal identity. Development. 1998 Feb;125(4):609-20
Assay type: RNA in situ
MGI Accession ID: MGI:1310061
Gene symbol: Phox2a
Gene name: paired-like homeobox 2a
Probe: pab9SSE
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen wild-type: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: sympathetic ganglion Strong 1A
TS20: enteric nervous system Strong Regionally restricted 1C Phox2a expression was observed in the foregut (esophageal) enteric ganglia.
TS20: esophagus Strong Regionally restricted 1C Phox2a expression was observed in the foregut (esophageal) enteric ganglia.
Specimen Mash1 -/-: embryonic day 12.5; Ascl1tm1And/Ascl1tm1And (more )
Structure Level Pattern Image Note
TS20: sympathetic ganglion Weak 1B
TS20: enteric nervous system Weak Regionally restricted 1D A striking reduction of Phox2a expression was observed in the foregut (esophageal) enteric ganglia.
TS20: esophagus Weak Regionally restricted 1D A striking reduction of Phox2a expression was observed in the foregut (esophageal) enteric ganglia.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
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