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Gene Expression Data
Assay Details
Assay
Reference: J:49909 Ba-Charvet KT, et al., A potential role for the OTX2 homeoprotein in creating early 'highways' for axon extension in the rostral brain. Development. 1998 Nov;125(21):4273-82
Assay type: Immunohistochemistry
MGI Accession ID: MGI:1289943
Gene symbol: Otx2
Gene name: orthodenticle homeobox 2
Antibody: Otx2 ab
Results
Specimen 1. A: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: diencephalon Strong Regionally restricted 1A Expression of Otx2 is elevated along several boundaries; the border between the dorsal and ventral thalamus, the ZLI, the alar/basal plate boundary and between the metencephalon and mesencephalon.
TS18: metencephalon Strong Regionally restricted 1A Expression of Otx2 is elevated along several boundaries; the border between the dorsal and ventral thalamus, the ZLI, the alar/basal plate boundary and between the metencephalon and mesencephalon.
TS18: metencephalon alar plate Strong Regionally restricted 1A Expression of Otx2 is elevated along several boundaries; the border between the dorsal and ventral thalamus, the ZLI, the alar/basal plate boundary and between the metencephalon and mesencephalon.
TS18: metencephalon basal plate Strong Regionally restricted 1A Expression of Otx2 is elevated along several boundaries; the border between the dorsal and ventral thalamus, the ZLI, the alar/basal plate boundary and between the metencephalon and mesencephalon.
TS18: midbrain Strong Regionally restricted 1A Expression of Otx2 is elevated along several boundaries; the border between the dorsal and ventral thalamus, the ZLI, the alar/basal plate boundary and between the metencephalon and mesencephalon.
TS18: myelencephalon alar plate Strong Regionally restricted 1A Expression of Otx2 is elevated along several boundaries; the border between the dorsal and ventral thalamus, the ZLI, the alar/basal plate boundary and between the metencephalon and mesencephalon.
TS18: myelencephalon basal plate Strong Regionally restricted 1A Expression of Otx2 is elevated along several boundaries; the border between the dorsal and ventral thalamus, the ZLI, the alar/basal plate boundary and between the metencephalon and mesencephalon.

Specimen 1. B: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: neural retinal epithelium Strong Uniform 1B
TS21: pigmented retinal epithelium Strong Uniform 1B
TS21: optic stalk Weak Uniform 1B

Specimen 1. C: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: thalamus Strong Regionally restricted 1C Strong expression is detected at the dorsal/ventral thalamus boundary and dorsal midline. Expression is also detected in the Dorsal and ventral thalamus proper as well as the pretectum.

Specimen 1. D: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: thalamus Strong Regionally restricted 1D Strong expression is detected at the dorsal/ventral thalamus border extending from the ventricle to the brain pial surface.

Specimen 1. E, F: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: thalamus Strong Regionally restricted 1F , 1E Strong expression is detected at the dorsal/ventral thalamus boundary.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory