Bw1 MGI Mouse QTL Detail - MGI:104777 - body weight QTL 1

About Help FAQ

Bw1 QTL Detail

Symbol

Bw1
Name

body weight QTL 1

Feature Type

QTL
IDs

MGI:104777
NCBI Gene: 109374
Candidate Genes

2 Genes

more

Sequence Map

ChrX:20606783-47179225 bp
From MGI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome X, cM position of peak correlated region/marker: Syntenic
Mapping Data

2 experiments

less

Phenotype Summary

1 phenotype reference

All Mutations and Alleles

3
QTL

3
Find Mice (IMSR)

0 strains or lines available

less

NCBI Gene

109374

less

MGD-MRK-28069

more

Summaries

All 4

Phenotypes 1
Earliest

J:29849 Dragani TA, et al., Mapping of body weight loci on mouse chromosome X. Mamm Genome. 1995 Nov;6(11):778-81
Latest

J:99477 Brown AC, et al., Searching QTL by gene expression: analysis of diabesity. BMC Genet. 2005 Mar 10;6(1):12

Candidate Genes for Bw1:

Gene	Genome Location (GRCm39)	Reference	QTL Note
Rab9	ChrX:165240249-165262863 (-)	J:99477	Authors used novel data mining tool ExQuest to identify novel candidate genes for existing diabesity QTLs. Next, candidate gene expression in the liver, adipose, and pancreas of diabesity-prone Tally Ho mice and diabesity-resistant C57BL/6J mice was assessed by quantitative PCR analysis. Several potential candidate genes, some with no previous association to diabesity QTLs, were identified. Since QTL intervals may be large and could contain hundreds or thousands of potential candidate genes, this method allows researchers to focus on those with strong potential as well as identify novel candidate genes. Potential candidate genes for QTLs Bw1 (18 cM) and Bw3 (32 cM) on mouse Chromosome X as identified by ExQuest are Rgn and Rab9, respectively.
Rgn	ChrX:20416026-20428328 (+)	J:99477	Authors used novel data mining tool ExQuest to identify novel candidate genes for existing diabesity QTLs. Next, candidate gene expression in the liver, adipose, and pancreas of diabesity-prone Tally Ho mice and diabesity-resistant C57BL/6J mice was assessed by quantitative PCR analysis. Several potential candidate genes, some with no previous association to diabesity QTLs, were identified. Since QTL intervals may be large and could contain hundreds or thousands of potential candidate genes, this method allows researchers to focus on those with strong potential as well as identify novel candidate genes. Potential candidate genes for QTLs Bw1 (18 cM) and Bw3 (32 cM) on mouse Chromosome X as identified by ExQuest are Rgn and Rab9, respectively.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23