| Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
  | arteriovenous malformations of the brain | ENG* | Eng* | 1 model | Alliance of Genome Resources | ||
| arteriovenous malformations of the brain | KRAS* | Kras* | 2 models | Alliance of Genome Resources | |||
| infantile myofibromatosis | PDGFRB* | Pdgfrb* | 1 model | Alliance of Genome Resources | |||
| pheochromocytoma | RET* | Ret* | 1 model | Alliance of Genome Resources | |||
| von Hippel-Lindau disease | VHL*, VHLL | Vhl* | 16 models | Alliance of Genome Resources | |||
| | arteriovenous malformations of the brain | ACVRL1 | Acvrl1* | 1 model | Alliance of Genome Resources | ||
| arteriovenous malformations of the brain | NOTCH4 | Notch4* | 1 model | Alliance of Genome Resources | |||
| dermoid cyst of ovary | FOXO3, FOXO3B | Foxo3* | 1 model | Alliance of Genome Resources | |||
| epidermal appendage tumor | TMEM207 | Tmem207* | 1 model | Alliance of Genome Resources | |||
| growth hormone secreting pituitary adenoma | MEN1 | Men1* | 1 model | Alliance of Genome Resources | |||
| hepatocellular adenoma | PTPN11 | Ptpn11* | 1 model | Alliance of Genome Resources | |||
| prolactinoma | MEN1 | Men1* | 1 model | Alliance of Genome Resources | |||
| uterine fibroid | TSC2 | Tsc2* | 1 model | Alliance of Genome Resources | |||
| | acoustic neuroma | ERCC2* | Ercc2 | Alliance of Genome Resources | |||
| acoustic neuroma | VEGFA* | Vegfa | Alliance of Genome Resources | ||||
| acoustic neuroma | CYP2E1* | Cyp2e1 | Alliance of Genome Resources | ||||
| ACTH-secreting pituitary adenoma | USP8* | Usp8 | Alliance of Genome Resources | ||||
| adrenal cortical adenoma | PRKACA* | Prkaca | Alliance of Genome Resources | ||||
| angiokeratoma | NAGA* | Naga | Alliance of Genome Resources | ||||
| appendiceal neoplasm | DAXX* | Daxx | Alliance of Genome Resources | ||||
| arteriovenous malformation | GLMN* | Glmn | Alliance of Genome Resources | ||||
| arteriovenous malformation | TEK* | Tek | Alliance of Genome Resources | ||||
| arteriovenous malformation | ENG* | Eng | Alliance of Genome Resources | ||||
| arteriovenous malformation | RASA1* | Rasa1 | Alliance of Genome Resources | ||||
| arteriovenous malformations of the brain | IL6* | Il6 | Alliance of Genome Resources | ||||
| bile duct adenoma | BRAF* | Braf | Alliance of Genome Resources | ||||
| biliary tract benign neoplasm | IL4* | Il4 | Alliance of Genome Resources | ||||
| biliary tract benign neoplasm | MUC1* | Muc1 | Alliance of Genome Resources | ||||
| biliary tract benign neoplasm | ALB* | Alb | Alliance of Genome Resources | ||||
| biliary tract benign neoplasm | MTAP* | Mtap | Alliance of Genome Resources | ||||
| choroid plexus papilloma | TP53* | Trp53 | Alliance of Genome Resources | ||||
| colorectal adenoma | PTGIS* | Ptgis | Alliance of Genome Resources | ||||
| colorectal adenoma | CYP24A1* | Cyp24a1 | Alliance of Genome Resources | ||||
| colorectal adenoma | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
| colorectal adenoma | GSTP1* | Gstp1, Gstp2, Gstp3, Gstp-ps | Alliance of Genome Resources | ||||
| colorectal adenoma | MAPK8* | Mapk8 | Alliance of Genome Resources | ||||
| dysembryoplastic neuroepithelial tumor | BRAF* | Braf | Alliance of Genome Resources | ||||
| endometrial hyperplasia | KRAS* | Kras | Alliance of Genome Resources | ||||
| familial hepatic adenoma | HNF1A* | Hnf1a | Alliance of Genome Resources | ||||
| fibroma | ANTXR2* | Antxr2 | Alliance of Genome Resources | ||||
| glomangioma | GLMN* | Glmn | Alliance of Genome Resources | ||||
| growth hormone secreting pituitary adenoma 2 | GPR101* | Gpr101 | Alliance of Genome Resources | ||||
| hepatic angiomyolipoma | TSC2* | Tsc2 | Alliance of Genome Resources | ||||
| hepatocellular adenoma | HNF1A* | Hnf1a | Alliance of Genome Resources | ||||
| infantile myofibromatosis | NOTCH3* | Notch3 | Alliance of Genome Resources | ||||
| insulinoma | INS* | Ins1, Ins2 | Alliance of Genome Resources | ||||
| kidney angiomyolipoma | MTOR* | Mtor | Alliance of Genome Resources | ||||
| liver benign neoplasm | TUT4* | Tut4 | Alliance of Genome Resources | ||||
| nephroma | DICER1* | Dicer1 | Alliance of Genome Resources | ||||
| neurilemmoma | CDKN2A* | Cdkn2a | Alliance of Genome Resources | ||||
| neurilemmoma | LZTR1* | Lztr1 | Alliance of Genome Resources | ||||
| neurilemmoma | NF2* | Nf2 | Alliance of Genome Resources | ||||
| pancreatic mucinous cystadenoma | KRAS* | Kras | Alliance of Genome Resources | ||||
| paraganglioma | DLST* | Dlst | Alliance of Genome Resources | ||||
| paraganglioma | SDHB* | Sdhb | Alliance of Genome Resources | ||||
| paraganglioma | SDHAF2* | Sdhaf2 | Alliance of Genome Resources | ||||
| paraganglioma | SDHA* | Sdha | Alliance of Genome Resources | ||||
| paraganglioma | SDHC* | Sdhc | 1 "NOT" model | Alliance of Genome Resources | |||
| paraganglioma | SDHD* | Sdhd | 3 "NOT" models | Alliance of Genome Resources | |||
| paraganglioma | SLC25A11* | Slc25a11 | Alliance of Genome Resources | ||||
| paranasal sinus benign neoplasm | TP53* | Trp53 | Alliance of Genome Resources | ||||
| pheochromocytoma | SDHB* | Sdhb | 1 model | Alliance of Genome Resources | |||
| pheochromocytoma | VHL*, VHLL | Vhl | Alliance of Genome Resources | ||||
| pheochromocytoma | TMEM127* | Tmem127 | Alliance of Genome Resources | ||||
| pheochromocytoma | MAX* | Max | Alliance of Genome Resources | ||||
| pheochromocytoma | HSD17B10* | Hsd17b10 | Alliance of Genome Resources | ||||
| pilomatrixoma | CTNNB1* | Ctnnb1 | Alliance of Genome Resources | ||||
| pituitary adenoma 1 | AIP* | Aip | Alliance of Genome Resources | ||||
| pituitary adenoma 3 | GNAS* | Gnas | Alliance of Genome Resources | ||||
| pituitary adenoma 5 | CDH23* | Cdh23 | Alliance of Genome Resources | ||||
| pleomorphic adenoma | PLAG1* | Plag1 | Alliance of Genome Resources | ||||
| pleomorphic xanthoastrocytoma | BRAF* | Braf | Alliance of Genome Resources | ||||
| rectal benign neoplasm | PIK3CA* | Pik3ca | Alliance of Genome Resources | ||||
| rectal benign neoplasm | MTHFR* | Mthfr | Alliance of Genome Resources | ||||
| rectal benign neoplasm | MAPK8* | Mapk8 | Alliance of Genome Resources | ||||
| seborrheic keratosis | PIK3CA* | Pik3ca | Alliance of Genome Resources | ||||
| skin benign neoplasm | HRAS* | Hras | Alliance of Genome Resources | ||||
| subserous uterine fibroid | TNRC6B* | Tnrc6b | Alliance of Genome Resources | ||||
| uterine fibroid | ADA* | Ada | Alliance of Genome Resources | ||||
| uterine fibroid | TNRC6B* | Tnrc6b | Alliance of Genome Resources | ||||
| uterine fibroid | NUAK1* | Nuak1 | Alliance of Genome Resources | ||||
| uterine fibroid | IRS1* | Irs1 | Alliance of Genome Resources | ||||
| uterine fibroid | COL6A3* | Col6a3 | Alliance of Genome Resources | ||||
| uterine fibroid | COL4A2* | Col4a2 | Alliance of Genome Resources | ||||
| uterine fibroid | COL4A1* | Col4a1 | Alliance of Genome Resources | ||||
| uterine fibroid | BET1L* | Bet1l | Alliance of Genome Resources | ||||
| uterine fibroid | GSTM5*, GSTM1 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
| uterine fibroid | DAPK1* | Dapk1 | Alliance of Genome Resources | ||||
| von Hippel-Lindau disease | MMP3* | Mmp3 | Alliance of Genome Resources | ||||
| von Hippel-Lindau disease | CCND1* | Ccnd1 | Alliance of Genome Resources | ||||
Excel File
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Transgenes and other genome features developed in mice to model this disease.
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| Disease Term | Transgenes and Other Genome Features | Mouse Models | |
| ACTH-secreting pituitary adenoma | Tg(PyLT)1Vb | 1 model | |
| arteriovenous malformations of the brain | Tg(tetO-Notch4*)1Rwng | 1 model | |
| choroid plexus papilloma | Tg(LPV-TAg121)2Tvd | 2 models | |
| dermoid cyst of ovary | Tg(Amh-SMAD2*)#Jebu | 1 model | |
| epidermal appendage tumor | Tg(Tff3-Tmem207)1Tamo | 1 model | |
| insulinoma | Tg(RIP1-Tag)2Dh | 1 model | |
| lung benign neoplasm | Tg(tetO/CMV-KRAS*G12C)9.1Msmi | 2 models | |
| prolactinoma | Tg(Prl-EGFR)#Sme | 1 model | |
| von Hippel-Lindau disease | Tg(Ggt1-Hif1a*)43Log | 1 model | |