Key:

hm	homozygous	ht	heterozygous	tg	involves transgenes	√	phenotype observed
cn	conditional genotype	cx	complex: > 1 genome feature	ot	other: hemizygous, indeterminate,...	N	normal phenotype

Genotype/
Background:

Phenotypes:

Affected Systems	hm1		hm2		hm3	cx4	cx5	cx6	cx7
show or hide all annotated terms Sex:
cellular				√	√				√
azoospermia				√
abnormal chiasmata formation					√
abnormal chromosomal synapsis									√
arrest of male meiosis				√
digestive/alimentary system	√	√					√	√
increased intestinal adenocarcinoma incidence	√	√					√	√
increased intestinal adenoma incidence	√	√					√	√
endocrine/exocrine glands			√
decreased corpora lutea number			√
abnormal ovarian folliculogenesis			√
small ovary			√
integument	√	√
increased skin tumor incidence	√	√
mortality/aging	√	√				√	√	√
premature death	√	√				√	√	√
preweaning lethality, incomplete penetrance	√	√
neoplasm	√	√	√	√		√	√	√
neoplasm						N
increased intestinal adenocarcinoma incidence	√	√					√	√
increased intestinal adenoma incidence	√	√					√	√
increased skin tumor incidence	√	√
increased lymphoma incidence	√	√	√	√		√	√	√
increased uterus tumor incidence	√
reproductive system	√		√	√	√				√
azoospermia				√
abnormal chiasmata formation					√
abnormal chromosomal synapsis									√
arrest of male meiosis				√
decreased corpora lutea number			√
abnormal ovarian folliculogenesis			√
small ovary			√
increased uterus tumor incidence	√
female infertility			√
male infertility				√