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All mouse models of macular degeneration with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | age related macular degeneration 4 | \Cfhtm1Mbo/\Cfhtm1Mbo | B6.129-Cfhtm1Mbo | J:203471 | View | |||
| age related macular degeneration 12 | \Cx3cr1tm1Zm/\Cx3cr1tm1Zm | C.129-Cx3cr1tm1Zm | J:127548 | View | ||||
| age related macular degeneration 12 | \Cx3cr1tm1Zm/\Cx3cr1tm1Zm | involves: 129 * C57BL/6 | J:127548 | View | ||||
| bestrophinopathy | \Best1tm1.1Amar/\Best1+ | involves: 129X1/SvJ * BALB/c | J:157645 | View | ||||
| bestrophinopathy | \Best1tm1.1Amar/\Best1tm1.1Amar | involves: 129X1/SvJ * BALB/c | J:157645 | View | ||||
| Doyne honeycomb retinal dystrophy | \Efemp1tm1Eap/\Efemp1+ | involves: 129S6/SvEvTac * C57BL/6 * FVB/N | J:129901 | View | ||||
| Doyne honeycomb retinal dystrophy | \Efemp1tm1Eap/\Efemp1tm1Eap | involves: 129S6/SvEvTac * C57BL/6 * FVB/N | J:129901 | View | ||||
| Doyne honeycomb retinal dystrophy | \Efemp1tm1Lmar/\Efemp1+ | involves: 129X1/SvJ * BALB/c | J:129902 | View | ||||
| Doyne honeycomb retinal dystrophy | \Efemp1tm1Lmar/\Efemp1tm1Lmar | involves: 129X1/SvJ * BALB/c | J:129902 | View | ||||
| patterned macular dystrophy 1 | \Prph2tm1.1Itl/\Prph2+ | Not Specified | J:215646 | View | ||||
| patterned macular dystrophy 1 | \Prph2tm1.1Itl/\Prph2tm1.1Itl | Not Specified | J:215646 | View | ||||
| patterned macular dystrophy 1 | \Prph2tm4.1Itl/\Prph2+ | Not Specified | J:292411 | View | ||||
| patterned macular dystrophy 1 | \Prph2tm4.1Itl/\Prph2tm4.1Itl | Not Specified | J:292411 | View | ||||
| patterned macular dystrophy 2 | \Ctnna1Tvrm5/\Ctnna1+ | C57BL/6J-Ctnna1Tvrm5/Pjn | J:227177 | View | ||||
| patterned macular dystrophy 2 | \Ctnna1Tvrm5/\Ctnna1Tvrm5 | C57BL/6J-Ctnna1Tvrm5/Pjn | J:227177 | View | ||||
| vitelliform macular dystrophy | \Best1tm1.1Amar/\Best1+ | involves: 129X1/SvJ * BALB/c | J:157645 | View | ||||
| vitelliform macular dystrophy | \Best1tm1.1Amar/\Best1tm1.1Amar | involves: 129X1/SvJ * BALB/c | J:157645 | View | ||||
| vitelliform macular dystrophy | \Impg2em1Visu/\Impg2em1Visu | involves: C57BL/6J * DBA/2 | J:288311 | View | ||||
| | age related macular degeneration | \Ccl2tm1Rol/\Ccl2tm1Rol | B6.129S4-Ccl2tm1Rol | J:147328 | View | |||
| age related macular degeneration |
\Ccl2tm1Rol/\Ccl2tm1Rol \Cx3cr1tm1Litt/\Cx3cr1tm1Litt |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6J | J:200877 | View | ||||
| age related macular degeneration |
\Ccl2tm1Rol/\Ccl2tm1Rol \Cx3cr1tm1Zm/\Cx3cr1tm1Zm |
involves: 129 * 129S4/SvJae | J:126935 | View | ||||
| age related macular degeneration | \Ccr2tm1Mae/\Ccr2tm1Mae | B6.129P2-Ccr2tm1Mae | J:147328 | View | ||||
| age related macular degeneration | \Cd46tm1Atk/\Cd46tm1Atk | B6.129-Cd46tm1Atk | J:234294 | View | ||||
| age related macular degeneration | \Ppargc1atm1Brsp/\Ppargc1a+ | involves: 129S4/SvJae * C57BL/6 | J:264271 | View | ||||
| age related macular degeneration 1 |
\Cryba1tm1.1Dbsa/\Cryba1tm1.1Dbsa \Tg(BEST1-cre)1Jdun/0 |
involves: 129S6/SvEvTac * C57BL/6 | J:215531 | View | ||||
| age related macular degeneration 1 | \Vldlrtm1Her/\Vldlrtm1Her | B6;129S7-Vldlrtm1Her/J | J:132497 | View | ||||
| Stargardt disease | \Abca4tm1.1Rsmy/\Abca4tm1.1Rsmy | involves: C57BL/6 | J:255529 | View | ||||
| Stargardt disease | \Abca4tm1Ght/\Abca4tm1Ght | involves: 129S4/SvJae | J:141801 | View | ||||
| Stargardt disease | \Abca4tm1Ght/\Abca4tm1Ght | involves: 129S4/SvJae * BALB/c | J:141801 | View | ||||
| Stargardt disease | \Abca4tm1Ght/\Abca4tm1Ght | involves: 129S4/SvJae * C57BL/6 | J:56317 | View | ||||
| Stargardt disease |
\Abca4tm1Kpal/\Abca4tm1Kpal \Rdh8tm1Kpal/\Rdh8tm1Kpal |
involves: 129 | J:213619 | View | ||||
| Stargardt disease | \Elovl4tm1Rayy/\Elovl4+ | involves: 129 * C57BL/6J | J:114752 | View | ||||
| Stargardt disease | \Elovl4tm1Wked/\Elovl4+ | involves: 129S/SvEv * 129S1/Sv | J:121481 | View | ||||
| | age related macular degeneration 1 | \Apoetm3(APOE*4)Mae/\Apoetm3(APOE*4)Mae | involves: 129P2/OlaHsd * C57BL/6 | J:101147 | View | |||
| age related macular degeneration 2 |
\Abca4tm1Ght/\Abca4tm1Ght \Rdh8tm1Kpal/\Rdh8tm1Kpal |
involves: 129 * 129S4/SvJae | J:154536 | View | ||||
| Transgenes and Other Mutations | age related macular degeneration 1 | \Tg(APOB)1102Sgy/? | B6.Cg-Tg(APOB)1102Sgy | J:151253 | View | |||
| Stargardt disease | \Tg(RBP3-ELOVL4*)1Kzh/0 | C57BL/6-Tg(RBP3-ELOVL4*)1Kzh | J:97173 | View | ||||
| Stargardt disease | \Tg(RBP3-ELOVL4*)2Kzh/0 | C57BL/6-Tg(RBP3-ELOVL4*)2Kzh | J:97173 | View | ||||
| Stargardt disease | \Tg(RBP3-ELOVL4*)3Kzh/0 | C57BL/6-Tg(RBP3-ELOVL4*)3Kzh | J:97173 | View | ||||
| Additional Complex Models | age related macular degeneration |
\Abca4tm1Kpal/\Abca4tm1Kpal \Rdh8tm1Kpal/\Rdh8tm1Kpal |
involves: 129 | J:213619 | View | |||
| age related macular degeneration 1 |
\Cptm1Hrs/\Cptm1Hrs \Hephsla/Y |
involves: 129X1/SvJ * C57BL/6 | J:136925 | View | ||||
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No similarity to the expected human disease phenotype was found.
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
| NOT Models | Stargardt disease | \Elovl4tm1Sie/\Elovl4+ | involves: 129P2/OlaHsd * C57BL/6 | J:112264 | View | |||
| Stargardt disease | \Elovl4tm1Sie/\Elovl4tm1Sie | involves: 129P2/OlaHsd * C57BL/6 | J:112264 | View | ||||
| vitelliform macular dystrophy | \Best1tm2.1Web/\Best1tm2.1Web | B6.129S1(Cg)-Best1tm2.1Web | J:280642 | View | ||||