Excel File Text File *Disease is associated/modeled with this Gene or a homolog. More...
      Disease Term Human Homologs Mouse Homologs Mouse Models Homology Source
     atypical teratoid rhabdoid tumor SMARCB1* Smarcb1* 3 models Alliance of Genome Resources
     glioblastoma TP53 Trp53* 2 models Alliance of Genome Resources
malignant astrocytoma HRAS Hras* 1 model Alliance of Genome Resources
medulloblastoma IFNG Ifng* 2 models Alliance of Genome Resources
medulloblastoma PTCH1 Ptch1* 12 models Alliance of Genome Resources
medulloblastoma SMO Smo* 8 models Alliance of Genome Resources
neuroblastoma LIN28B Lin28b* 1 model Alliance of Genome Resources
uveal melanoma GRM1 Grm1* 1 model Alliance of Genome Resources
     astroblastoma PIK3R1* Pik3r1   Alliance of Genome Resources
brain cancer TERT* Tert   Alliance of Genome Resources
brain cancer CCDC26*  
brain cancer CDKN2B-AS1*  
brain glioma PTPRB* Ptprb   Alliance of Genome Resources
brain glioma ADAM3A* Adam3   Alliance of Genome Resources
central nervous system lymphoma MYD88* Myd88   Alliance of Genome Resources
central nervous system lymphoma IL10* Il10   Alliance of Genome Resources
central nervous system lymphoma CD79B* Cd79b   Alliance of Genome Resources
central nervous system lymphoma BTK* Btk   Alliance of Genome Resources
childhood astrocytic tumor RTEL1* Rtel1   Alliance of Genome Resources
conjunctival squamous cell carcinoma ADAM3A* Adam3   Alliance of Genome Resources
familial meningioma NF2* Nf2 1 model Alliance of Genome Resources
familial meningioma MN1* Mn1   Alliance of Genome Resources
familial meningioma SMARCE1* Smarce1   Alliance of Genome Resources
familial meningioma SUFU* Sufu   Alliance of Genome Resources
familial meningioma PTEN* Pten   Alliance of Genome Resources
familial meningioma PDGFB* Pdgfb   Alliance of Genome Resources
familial retinoblastoma RB1* Rb1   Alliance of Genome Resources
glioblastoma CDK4* Cdk4   Alliance of Genome Resources
glioblastoma ADGRB1* Adgrb1   Alliance of Genome Resources
glioblastoma AKT3* Akt3   Alliance of Genome Resources
glioblastoma CDKN2A* Cdkn2a   Alliance of Genome Resources
glioblastoma DMBT1* Dmbt1   Alliance of Genome Resources
glioblastoma EGF* Egf   Alliance of Genome Resources
glioblastoma EZH2* Ezh2   Alliance of Genome Resources
glioblastoma FLT3LG* Flt3l   Alliance of Genome Resources
glioblastoma IDH1* Idh1   Alliance of Genome Resources
glioblastoma KDR* Kdr   Alliance of Genome Resources
glioblastoma LZTR1* Lztr1   Alliance of Genome Resources
glioblastoma MAP1LC3A* Map1lc3a   Alliance of Genome Resources
glioblastoma MDM2* Mdm2   Alliance of Genome Resources
glioblastoma MGMT* Mgmt   Alliance of Genome Resources
glioblastoma MMP9* Mmp9   Alliance of Genome Resources
glioblastoma NFKBIA* Nfkbia   Alliance of Genome Resources
glioblastoma NRAS* Nras   Alliance of Genome Resources
glioblastoma PDGFB* Pdgfb   Alliance of Genome Resources
glioblastoma PDGFRB* Pdgfrb   Alliance of Genome Resources
glioblastoma PGF* Pgf   Alliance of Genome Resources
glioblastoma PIK3CB* Pik3cb   Alliance of Genome Resources
glioblastoma PTPRB* Ptprb   Alliance of Genome Resources
glioblastoma RB1* Rb1   Alliance of Genome Resources
glioblastoma RPL5* Rpl5   Alliance of Genome Resources
malignant astrocytoma BRAF* Braf   Alliance of Genome Resources
malignant astrocytoma CADM2* Cadm2   Alliance of Genome Resources
malignant astrocytoma GSTM1*, GSTM5 Gstm1, Gstm2, Gstm3, Gstm6   Alliance of Genome Resources
malignant astrocytoma GSTP1* Gstp1, Gstp2, Gstp3, Gstp-ps   Alliance of Genome Resources
malignant astrocytoma KRAS* Kras   Alliance of Genome Resources
malignant peripheral nerve sheath tumor KDM4B* Kdm4b   Alliance of Genome Resources
medulloblastoma CTNNB1* Ctnnb1   Alliance of Genome Resources
medulloblastoma APC* Apc   Alliance of Genome Resources
medulloblastoma BRCA2* Brca2 2 models Alliance of Genome Resources
medulloblastoma ELP1* Elp1   Alliance of Genome Resources
medulloblastoma GSTM1*, GSTM5 Gstm1, Gstm2, Gstm3, Gstm6   Alliance of Genome Resources
medulloblastoma GSTT1* Gstt1   Alliance of Genome Resources
medulloblastoma PTCH2* Ptch2 2 models Alliance of Genome Resources
medulloblastoma SUFU* Sufu 1 model Alliance of Genome Resources
medulloblastoma TSC2* Tsc2   Alliance of Genome Resources
meningioma GSTM3* Gstm5   Alliance of Genome Resources
meningioma SMARCE1* Smarce1   Alliance of Genome Resources
meningioma NF2* Nf2   Alliance of Genome Resources
meningioma MTRR* Mtrr   Alliance of Genome Resources
meningioma MN1* Mn1   Alliance of Genome Resources
neuroblastoma PHOX2B* Phox2b   Alliance of Genome Resources
neuroblastoma ARID1A* Arid1a   Alliance of Genome Resources
neuroblastoma ARID1B* Arid1b   Alliance of Genome Resources
neuroblastoma CDKN2A* Cdkn2a   Alliance of Genome Resources
neuroblastoma CHAF1A* Chaf1a   Alliance of Genome Resources
neuroblastoma IGF1R* Igf1r   Alliance of Genome Resources
neuroblastoma KIF1B* Kif1b   Alliance of Genome Resources
neuroblastoma NSD1* Nsd1   Alliance of Genome Resources
neuroblastoma PECAM1* Pecam1   Alliance of Genome Resources
neuroblastoma NME1* Nme1   Alliance of Genome Resources
neurofibrosarcoma MXI1* Mxi1   Alliance of Genome Resources
optic nerve glioma NF1* Nf1   Alliance of Genome Resources
peripheral nervous system neoplasm PTEN* Pten   Alliance of Genome Resources
plexiform neurofibroma NF1* Nf1   Alliance of Genome Resources
retinoblastoma MGMT* Mgmt   Alliance of Genome Resources
retinoblastoma MTR* Mtr   Alliance of Genome Resources
retinoblastoma RB1* Rb1 3 models Alliance of Genome Resources
retinoblastoma SERPINF1* Serpinf1   Alliance of Genome Resources
third ventricle chordoid glioma PRKCA* Prkca   Alliance of Genome Resources
uveal melanoma BRCA2* Brca2   Alliance of Genome Resources
uveal melanoma SERPINE1* Serpine1   Alliance of Genome Resources

 
Transgenes and other genome features developed in mice to model this disease.
     Disease Term Transgenes and Other Genome Features Mouse Models
  malignant astrocytoma Tg(GFAP-Hras1)2Agu 1 model
  malignant astrocytoma Tg(GFAP-SRC)1Aag 1 model
  malignant astrocytoma Tg(GFAP-SRC)2Aag 1 model
  malignant astrocytoma Tg(GFAP-TAg121)1Tvd 2 models
  medulloblastoma Tg(Neurod2-Smo*A1)199Jols 3 models
  medulloblastoma Tg(Neurod2-Smo*A2)#Jols 1 model
  medulloblastoma Tg(tetO-Ifng)184Pop 2 models
  medulloblastoma Tg(tetO-MYCN,-luc)#Waw 2 models
  medulloblastoma Tg(tetO-TAg,CMV-rtTA)123Yihu 1 model
  neuroblastoma Tg(Th-MYCN)41Waw 14 models
  neuroblastoma Tg(tetO-TAg)2-5Hiwa 1 model
  neuroblastoma Tg(rTH-Tag)20Dmc 1 model
  neuroblastoma Tg(OMP-SV40T)13Bse 1 model
  neuroblastoma Tg(CAG-Alk*F1174L,-luc)60Jhsc 3 models
  retinal cancer Tg(Tyrp1-TAg)3434Bee 1 model
  retinoblastoma Tg(Pax6-TAg)1796Hur 1 model
  retinoblastoma Tg(TagRb)1Plm 1 model
  retinoblastoma Tg(Rbp3-SV40)IT-2Jjw 1 model
  uveal melanoma Tg(Dct-Grm1)ESzc 1 model