Excel File Text File All mouse models of CADASIL with phenotypic similarity to the human disease
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
      autosomal dominant cerebral arteriopathy with subcortical infarcts and leukoencephalopathy 1 Gt(ROSA)26Sortm2(NOTCH3*C455R)Sat/Gt(ROSA)26Sor+
Notch3Gt(PST033)Byg/Notch3Gt(PST033)Byg
Tg(Tagln-cre)1Her/0
involves: 129 * C57BL/6 * SJL J:171887 View
autosomal dominant cerebral arteriopathy with subcortical infarcts and leukoencephalopathy 1 Gt(ROSA)26Sortm3(NOTCH3*R1031C)Sat/Gt(ROSA)26Sor+
Notch3Gt(PST033)Byg/Notch3Gt(PST033)Byg
Tg(Tagln-cre)1Her/0
involves: 129 * C57BL/6 * SJL J:171887 View
autosomal dominant cerebral arteriopathy with subcortical infarcts and leukoencephalopathy 1 Notch1tm1Grid/Notch1+
Notch3tm1Grid/Notch3tm1Grid
involves: 129S1/Sv * C57BL/6 J:227333 View
autosomal dominant cerebral arteriopathy with subcortical infarcts and leukoencephalopathy 1 Notch3hpbk/Notch3hpbk C57BL/6J-Notch3hpbk/GrsrJ J:222308 View
autosomal dominant cerebral arteriopathy with subcortical infarcts and leukoencephalopathy 1 Notch3tm1.1Dwr/Notch3+ involves: 129S/SvEv * Swiss J:191454 View
autosomal dominant cerebral arteriopathy with subcortical infarcts and leukoencephalopathy 1 Notch3tm1.1Dwr/Notch3tm1.1Dwr involves: 129S/SvEv * Swiss J:191454 View
Transgenes and
Other Mutations
     autosomal dominant cerebral arteriopathy with subcortical infarcts and leukoencephalopathy 1 Tg(Notch3*R169C)88Bbb/0 involves: FVB/N J:220006 View
Additional
Complex
Models
     autosomal dominant cerebral arteriopathy with subcortical infarcts and leukoencephalopathy 1 Gt(ROSA)26Sortm3(NOTCH3*R1031C)Sat/Gt(ROSA)26Sor+
Tg(Tagln-cre)1Her/0
involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * SJL J:171887 View


       
No similarity to the expected human disease phenotype was found.
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
NOT Models      autosomal dominant cerebral arteriopathy with subcortical infarcts and leukoencephalopathy 1 Notch3tm1Grid/Notch3tm1Grid involves: 129S1/Sv * C57BL/6 J:227333 View
autosomal dominant cerebral arteriopathy with subcortical infarcts and leukoencephalopathy 1 Notch3tm1Ul/Notch3+ Not Specified J:95927 View
autosomal dominant cerebral arteriopathy with subcortical infarcts and leukoencephalopathy 1 Notch3tm1Ul/Notch3tm1Ul Not Specified J:95927 View