Excel File Text File All mouse models of CADASIL with phenotypic similarity to the human disease
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
      CADASIL 1 Gt(ROSA)26Sortm2(NOTCH3*C455R)Sat/Gt(ROSA)26Sor+
Notch3Gt(PST033)Byg/Notch3Gt(PST033)Byg
Tg(Tagln-cre)1Her/0
involves: 129 * C57BL/6 * SJL J:171887 View
CADASIL 1 Gt(ROSA)26Sortm3(NOTCH3*R1031C)Sat/Gt(ROSA)26Sor+
Notch3Gt(PST033)Byg/Notch3Gt(PST033)Byg
Tg(Tagln-cre)1Her/0
involves: 129 * C57BL/6 * SJL J:171887 View
CADASIL 1 Notch1tm1Grid/Notch1+
Notch3tm1Grid/Notch3tm1Grid
involves: 129S1/Sv * C57BL/6 J:227333 View
CADASIL 1 Notch3hpbk/Notch3hpbk C57BL/6J-Notch3hpbk/GrsrJ J:222308 View
CADASIL 1 Notch3tm1.1Dwr/Notch3+ involves: 129S/SvEv * Swiss J:191454 View
CADASIL 1 Notch3tm1.1Dwr/Notch3tm1.1Dwr involves: 129S/SvEv * Swiss J:191454 View
Transgenes and
Other Mutations
     CADASIL 1 Tg(Notch3*R169C)88Bbb/0 involves: FVB/N J:220006 View
Additional
Complex
Models
     CADASIL 1 Gt(ROSA)26Sortm3(NOTCH3*R1031C)Sat/Gt(ROSA)26Sor+
Tg(Tagln-cre)1Her/0
involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * SJL J:171887 View


       
No similarity to the expected human disease phenotype was found.
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
NOT Models      CADASIL 1 Notch3tm1Grid/Notch3tm1Grid involves: 129S1/Sv * C57BL/6 J:227333 View
CADASIL 1 Notch3tm1Ul/Notch3+ Not Specified J:95927 View
CADASIL 1 Notch3tm1Ul/Notch3tm1Ul Not Specified J:95927 View