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All mouse models of spinal muscular atrophy with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | autosomal recessive distal hereditary motor neuronopathy 1 | Ighmbp2em1Cll/Ighmbp2em1Cll | FVB/NJ-Ighmbp2em1Cll | J:326540 | View | |||
| autosomal recessive distal hereditary motor neuronopathy 1 | Ighmbp2nmd-2J/Ighmbp2nmd-2J | B6.BKS-Ighmbp2nmd-2J/J | J:92862 | View | ||||
| juvenile spinal muscular atrophy | Smn1tm1.1Dscd/Smn1tm1.1Dscd | involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 | J:164889 | View | ||||
| juvenile spinal muscular atrophy |
Smn1tm1Msd/Smn1tm1Msd Tg(SMN1*A2G)2023Ahmb/0 Grm7Tg(SMN2)89Ahmb/Grm7+ |
involves: 129P2/OlaHsd * FVB/N | J:81238 | View | ||||
| Werdnig-Hoffmann disease |
Mnx1tm4(cre)Tmj/Mnx1+ Smn1tm1Cdid/Smn1tm1Cdid Grm7Tg(SMN2)89Ahmb/Grm7+ |
involves: 129 * 129S1/Sv * C57BL/6 * FVB | J:183080 | View | ||||
| Werdnig-Hoffmann disease |
Olig2tm1(cre)Tmj/Olig2+ Smn1tm1Jme/Smn1tm1Msd Grm7Tg(SMN2)89Ahmb/Grm7Tg(SMN2)89Ahmb |
involves: 129 * 129P2/OlaHsd * FVB/N | J:164292 | View | ||||
| Werdnig-Hoffmann disease |
Smn1tm1Cdid/Smn1tm1Cdid Grm7Tg(SMN2)89Ahmb/Grm7+ |
involves: 129 * C57BL/6 * FVB | J:183080 | View | ||||
| Werdnig-Hoffmann disease |
Smn1tm1Hung/Smn1tm1Hung Tg(SMN2)2Hung/Tg(SMN2)2Hung |
involves: 129P2/OlaHsd * FVB/N | J:59313 | View | ||||
| Werdnig-Hoffmann disease |
Smn1tm1Jme/Smn1tm1.1Jme Tg(ACTA1-cre)79Jme/0 |
involves: 129 * C57BL/6J * SJL | J:67884 | View | ||||
| Werdnig-Hoffmann disease |
Smn1tm1Jme/Smn1tm1.1Jme Tg(Eno2-cre)39Jme/0 |
involves: 129 * C57BL/6J * SJL | J:61396 | View | ||||
| Werdnig-Hoffmann disease |
Smn1tm1Jme/Smn1tm1Jme Tg(Eno2-cre)39Jme/0 |
involves: 129 * C57BL/6J * SJL | J:89836 | View | ||||
| Werdnig-Hoffmann disease |
Smn1tm1Msd/Smn1tm1Msd Grm7Tg(SMN2)89Ahmb/? |
involves: 129P2/OlaHsd * C57BL/6J * FVB | J:60592 | View | ||||
| Werdnig-Hoffmann disease |
Smn1tm1Msd/Smn1tm1Msd Grm7Tg(SMN2)89Ahmb/Grm7Tg(SMN2)89Ahmb Tg(SMN2*delta7)4299Ahmb/Tg(SMN2*delta7)4299Ahmb |
FVB.Cg-Grm7Tg(SMN2)89Ahmb Smn1tm1Msd Tg(SMN2*delta7)4299Ahmb | J:97103 | View | ||||
| Werdnig-Hoffmann disease |
Smn1tm1Msd/Smn1tm1Msd Grm7Tg(SMN2)89Ahmb/Grm7Tg(SMN2)89Ahmb Tg(SMN2*delta7)4299Ahmb/Tg(SMN2*delta7)4299Ahmb |
FVB.Cg-Grm7Tg(SMN2)89Ahmb Smn1tm1Msd Tg(SMN2*delta7)4299Ahmb/J | J:164446 | View | ||||
| Werdnig-Hoffmann disease |
Smn1tm1Msd/Smn1tm1Msd Grm7Tg(SMN2)89Ahmb/Grm7Tg(SMN2)89Ahmb Tg(SMN2*delta7)4299Ahmb/Tg(SMN2*delta7)4299Ahmb |
involves: 129P2/OlaHsd * FVB/N | J:164444 | View | ||||
| Werdnig-Hoffmann disease |
Smn1tm1Msd/Smn1tm1Msd Tg(ACTA1-SMN)69Ahmb/Tg(ACTA1-SMN)69Ahmb Grm7Tg(SMN2)89Ahmb/Grm7Tg(SMN2)89Ahmb |
involves: 129P2/OlaHsd * FVB/N | J:131663 | View | ||||
| Werdnig-Hoffmann disease |
Smn1tm1Msd/Smn1tm1Msd Tg(Prnp-SMN)92Ahmb/Tg(Prnp-SMN)92Ahmb Grm7Tg(SMN2)89Ahmb/Grm7Tg(SMN2)89Ahmb |
involves: 129P2/OlaHsd * FVB/N | J:131663 | View | ||||
| Werdnig-Hoffmann disease |
Smn1tm1Msd/Smn1tm1Msd Tg(SMN1*A2G)2023Ahmb/0 Grm7Tg(SMN2)89Ahmb/Grm7Tg(SMN2)89Ahmb |
involves: 129P2/OlaHsd * FVB/N | J:131663 | View | ||||
| Werdnig-Hoffmann disease |
Smn1tm1Msd/Smn1tm1Msd Tg(SMN1-SMN2*)16Cll/0 Grm7Tg(SMN2)89Ahmb/Grm7Tg(SMN2)89Ahmb |
involves: 129P2/OlaHsd * C57BL/6 * FVB/N | J:194969 | View | ||||
| Werdnig-Hoffmann disease |
Smn1tm1Msd/Smn1tm1Msd Tg(SMN2)11Tro/0 Tg(SMN2)46Tro/0 |
B6.Cg-Tg(SMN2)11Tro Tg(SMN2)46Tro Smn1tm1Msd/J | J:159930 | View | ||||
| Werdnig-Hoffmann disease | Smn1tm1Msd/Smn1tm1Rako | involves: 129P2/OlaHsd * C57BL/6 * CD-1 | J:154248 | View | ||||
| X-linked distal spinal muscular atrophy 3 |
Atp7atm1.1Mjp/Y Mnx1tm4(cre)Tmj/Mnx1+ |
involves: 129S1/Sv * C57BL/6 | J:221066 | View | ||||
| X-linked distal spinal muscular atrophy 3 | Atp7atm1.2Mlke/Y | involves: C57BL/6J | J:266704 | View | ||||
| | autosomal dominant distal hereditary motor neuronopathy 2 | Hspb8tm1Vti/Hspb8tm1Vti | involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NCrl | J:284796 | View | |||
| Werdnig-Hoffmann disease | Vps54wr/Vps54wr | multiple strains | J:6388 | View | ||||
| | intermediate spinal muscular atrophy | Smn1tm5(Smn1/SMN2)Mrph/Smn1tm5(Smn1/SMN2)Mrph | involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NTac | J:186987 | View | |||
| Kennedy's disease | Artm4(AR)Dmr/Y | involves: 129S1/Sv * C57BL/6J | J:104360, J:114552 | View | ||||
| Transgenes and Other Mutations | Kennedy's disease | Tg(ACTA1-Ar)141Kyjo/0 | Not Specified | J:127205 | View | |||
| Kennedy's disease | Tg(AR*100Q)#Als/0 | involves: 129S1/Sv * 129X1/SvJ * C57BL/6J | J:170487 | View | ||||
| Kennedy's disease | Tg(AR*100Q)C25Als/0 | involves: 129S1/Sv * 129X1/SvJ * C57BL/6J | J:89772 | View | ||||
| Kennedy's disease | Tg(AR*100Q)C32Als/0 | involves: 129S1/Sv * 129X1/SvJ * C57BL/6J | J:89772 | View | ||||
| Kennedy's disease | Tg(CAG-AR*97Q)7-8Sobue/? | involves: C57BL/6 * C57BL/6J * DBA/2 | J:128519 | View | ||||
| Kennedy's disease | Tg(Prnp-AR*112Q)#Deme/0 | involves: C57BL/6 * SJL | J:134789 | View | ||||