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All mouse models of cerebral cavernous malformation with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | cerebral cavernous malformation |
Krit1tm1Kwhi/Krit1tm1Kwhi Tg(Cdh5-cre/ERT2)1Rha/0 |
involves: 129S6/SvEvTac * C57BL/6NCrl | J:232707, J:250906 | View | |||
| cerebral cavernous malformation 2 |
Ccm2tm1.1Etl/Ccm2tm1Etl Tg(Cdh5-cre/ERT2)1Rha/0 |
involves: 129 * C57BL/6 | J:177584 | View | ||||
| cerebral cavernous malformation 2 |
Ccm2tm1Kwhi/Ccm2tm1.1Kwhi Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/? |
involves: C57BL/6 * CBA | J:173947 | View | ||||
| cerebral cavernous malformation 2 |
Ccm2tm1Mlkn/Ccm2tm1Mlkn Tg(Cdh5-cre/ERT2)1Rha/0 |
involves: 129 | J:250906 | View | ||||
| cerebral cavernous malformation 2 |
Ccm2tm2.1Sbn/Ccm2tm2.1Sbn Tg(Mx1-cre)1Cgn/0 |
involves: C57BL/6 * CBA | J:174085 | View | ||||
| cerebral cavernous malformation 3 |
Pdcd10tm1Kwhi/Pdcd10tm1.1Kwhi Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/? |
involves: C57BL/6 * CBA | J:173947 | View | ||||
| cerebral cavernous malformation 3 |
Pdcd10tm1Wami/Pdcd10tm1Wami Tg(GFAP-cre)25Mes/0 |
involves: 129 * C57BL/6 * FVB/N | J:170480 | View | ||||
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No similarity to the expected human disease phenotype was found.
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
| NOT Models | cerebral cavernous malformation 2 |
Ccm2tm1Etl/Ccm2tm1Etl Tg(Nes-cre)1Kln/? |
B6.Cg-Ccm2tm1Etl Tg(Nes-cre)1Kln | J:146210 | View | |||
| cerebral cavernous malformation 2 |
Ccm2tm2.1Sbn/Ccm2tm2.1Sbn Tg(Tek-cre)1Ywa/0 |
involves: C57BL/6 * SJL | J:174085 | View | ||||