| Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
  | frontotemporal dementia | CHMP2B* | Chmp2b* | 1 model | Alliance of Genome Resources | ||
| Grn-related frontotemporal lobar degeneration with Tdp43 inclusions | GRN* | Grn* | 3 models | Alliance of Genome Resources | |||
| | frontotemporal dementia | TARDBP | Tardbp* | 2 models | Alliance of Genome Resources | ||
| frontotemporal dementia | TREM2 | Trem2* | 1 model | Alliance of Genome Resources | |||
| frontotemporal dementia | VCP | Vcp* | 1 model | Alliance of Genome Resources | |||
| Grn-related frontotemporal lobar degeneration with Tdp43 inclusions | TARDBP | Tardbp* | 1 model | Alliance of Genome Resources | |||
| | frontotemporal dementia | GRN* | Grn | Alliance of Genome Resources | |||
| frontotemporal dementia | MAPT* | Mapt | Alliance of Genome Resources | ||||
| frontotemporal dementia | MOBP* | Mobp | Alliance of Genome Resources | ||||
| frontotemporal dementia | PSEN1* | Psen1 | Alliance of Genome Resources | ||||
| frontotemporal dementia and/or amyotrophic lateral sclerosis 7 | CHMP2B* | Chmp2b | Alliance of Genome Resources | ||||
| Pick's disease | PSEN1* | Psen1 | Alliance of Genome Resources | ||||
| Pick's disease | MAP2K6* | Map2k6 | Alliance of Genome Resources | ||||
| Pick's disease | MAPT* | Mapt | Alliance of Genome Resources | ||||
Excel File
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Transgenes and other genome features developed in mice to model this disease.
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| Disease Term | Transgenes and Other Genome Features | Mouse Models | |
| frontotemporal dementia | Tg(tetO-CHMP2B*)3Fbga | 1 model | |
| frontotemporal dementia | Tg(Thy1-MAPT*)1Avil | 1 model | |
| frontotemporal dementia | Tg(Thy1-MAPT*K369I)K3Gotz | 1 model | |
| frontotemporal dementia | Tg(Thy1-MAPT*P301S)2541Godt | 1 model | |
| frontotemporal dementia | Tg(Thy1-MAPT*V337M)1Godt | 1 model | |
| frontotemporal dementia | Tg(Thy1-TARDBP)4Singh | 2 models | |
| frontotemporal dementia | Tg(Thy1-TARDBP)6Singh | 1 model | |
| frontotemporal dementia | Tg(Tuba1-MAPT)14Vle | 1 model | |
| frontotemporal dementia | Tg(Camk2a-MAPT)601Ymot | 1 model | |
| frontotemporal dementia | Tg(Camk2a-MAPT*P301L)D35Jiri | 1 model | |
| frontotemporal dementia | Tg(Camk2a-MAPT*R406W)748Atak | 1 model | |
| frontotemporal dementia | Tg(MAPT*V337M)1Gds | 1 model | |
| frontotemporal dementia | Tg(PDGFB-MAPT*V337M)1Atak | 1 model | |
| frontotemporal dementia | Tg(Prnp-MAPT)7Vle | 1 model | |
| frontotemporal dementia | Tg(Prnp-MAPT)43Vle | 1 model | |
| frontotemporal dementia | Tg(Prnp-MAPT*P301L)JNPL3Hlmc | 1 model | |
| frontotemporal dementia | Tg(Prnp-MAPT*P301S)50Hiw | 1 model | |
| frontotemporal dementia | Tg(Prnp-MAPT*R406W)21807Dwst | 1 model | |
| frontotemporal dementia | Tg(Prnp-TARDBP*A315T)95Balo | 1 model | |
| Grn-related frontotemporal lobar degeneration with Tdp43 inclusions | Tg(TARDBP)#Jpj | 1 model | |
| Grn-related frontotemporal lobar degeneration with Tdp43 inclusions | Tg(TARDBP*G348C)#Jpj | 1 model | |
| Grn-related frontotemporal lobar degeneration with Tdp43 inclusions | Tg(Thy1-TARDBP*)BOddo | 2 models | |
| Grn-related frontotemporal lobar degeneration with Tdp43 inclusions | Tg(TARDBP*A315T)#Jpj | 1 model | |
| Grn-related frontotemporal lobar degeneration with Tdp43 inclusions | Tg(Camk2a-Tardbp)#Ckjs | 1 model | |
| Grn-related frontotemporal lobar degeneration with Tdp43 inclusions | Tg(Prnp-TARDBP)3cPtrc | 1 model | |
| Pick's disease | Tg(Thy1-MAPT*L266V*G272V)13Ema | 1 model | |