Key:
hm homozygous ht heterozygous tg involves transgenes phenotype observed
cn conditional genotype  cx complex: > 1 genome feature ot other: hemizygous, indeterminate,... N normal phenotype
Genotype/
Background:
Phenotypes:
Affected Systems
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hematopoietic system
hematopoietic system phenotype
N N
decreased neutrophil cell number
impaired neutrophil recruitment
decreased platelet aggregation
abnormal platelet dense granule physiology
homeostasis/metabolism
decreased platelet aggregation
abnormal platelet dense granule physiology
decreased susceptibility to induced thrombosis
increased bleeding time
immune system
decreased neutrophil cell number
impaired neutrophil recruitment