MGI MouseCyc experimental GO annotations for PWY-5913

MGI MouseCyc experimental GO annotations for PWY-5913: TCA cycle variation IV

Roles of genes might be detected in a summary/comparison table of high level GO categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";
Black arrows indicate "regulates";
Green arrows indicate "positively_regulates";
Red arrows indicate "negatively_regulates"

Compare annotations to GO categories for PWY-5913: TCA cycle variation IV

Entry indicates that gene is in this pathway.
Colored entries indicate GO annotation.

Category	ID	Term	Aco1	Aco2	Cs	Csl	Fh1	Glud1	Glud2	Got1	Got2	Idh1	Idh2	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
Molecular Function	GO:0005488	binding	Aco1	Aco2	Cs	Csl	Fh1	Glud1	Glud2	Got1	Got2	Idh1	Idh2	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
Molecular Function	GO:0003824	catalytic activity	Aco1	Aco2	Cs	Csl	Fh1	Glud1	Glud2	Got1	Got2	Idh1	Idh2	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
Cellular Component	GO:0005623	cell	Aco1	Aco2	Cs	Csl	Fh1	Glud1	Glud2	Got1	Got2	Idh1	Idh2	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
Cellular Component	GO:0044464	cell part	Aco1	Aco2	Cs	Csl	Fh1	Glud1	Glud2	Got1	Got2	Idh1	Idh2	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
Cellular Component	GO:0031975	envelope	Aco1	Aco2	Cs	Csl	Fh1	Glud1	Glud2	Got1	Got2	Idh1	Idh2	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
Cellular Component	GO:0043226	organelle	Aco1	Aco2	Cs	Csl	Fh1	Glud1	Glud2	Got1	Got2	Idh1	Idh2	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
Cellular Component	GO:0044422	organelle part	Aco1	Aco2	Cs	Csl	Fh1	Glud1	Glud2	Got1	Got2	Idh1	Idh2	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
Biological Process	GO:0065007	biological regulation	Aco1	Aco2	Cs	Csl	Fh1	Glud1	Glud2	Got1	Got2	Idh1	Idh2	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
Biological Process	GO:0009987	cellular process	Aco1	Aco2	Cs	Csl	Fh1	Glud1	Glud2	Got1	Got2	Idh1	Idh2	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
Biological Process	GO:0032502	developmental process	Aco1	Aco2	Cs	Csl	Fh1	Glud1	Glud2	Got1	Got2	Idh1	Idh2	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
Biological Process	GO:0051234	establishment of localization	Aco1	Aco2	Cs	Csl	Fh1	Glud1	Glud2	Got1	Got2	Idh1	Idh2	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
Biological Process	GO:0051179	localization	Aco1	Aco2	Cs	Csl	Fh1	Glud1	Glud2	Got1	Got2	Idh1	Idh2	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
Biological Process	GO:0008152	metabolic process	Aco1	Aco2	Cs	Csl	Fh1	Glud1	Glud2	Got1	Got2	Idh1	Idh2	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
Biological Process	GO:0032501	multicellular organismal process	Aco1	Aco2	Cs	Csl	Fh1	Glud1	Glud2	Got1	Got2	Idh1	Idh2	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
Biological Process	GO:0048519	negative regulation of biological process	Aco1	Aco2	Cs	Csl	Fh1	Glud1	Glud2	Got1	Got2	Idh1	Idh2	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
Biological Process	GO:0050789	regulation of biological process	Aco1	Aco2	Cs	Csl	Fh1	Glud1	Glud2	Got1	Got2	Idh1	Idh2	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
Biological Process	GO:0050896	response to stimulus	Aco1	Aco2	Cs	Csl	Fh1	Glud1	Glud2	Got1	Got2	Idh1	Idh2	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2

Full set of annotations for PWY-5913: TCA cycle variation IV

Category	ID	Term	Mouse gene	Evidence	Color Key
Molecular Function	GO:0003994	aconitate hydratase activity	Aco1	IDA	color key
Molecular Function	GO:0003994	aconitate hydratase activity	Aco2	IDA	color key
Molecular Function	GO:0004069	aspartate transaminase activity	Got1	IDA	color key
Molecular Function	GO:0004069	aspartate transaminase activity	Got2	IDA	color key
Molecular Function	GO:0004353	glutamate dehydrogenase [NAD(P)+] activity	Glud1	IDA	color key
Molecular Function	GO:0030350	iron-responsive element binding	Aco1	IDA	color key
Molecular Function	GO:0004450	isocitrate dehydrogenase (NADP+) activity	Idh1	IDA	color key
Molecular Function	GO:0004450	isocitrate dehydrogenase (NADP+) activity	Idh2	IDA	color key
Molecular Function	GO:0030060	L-malate dehydrogenase activity	Mdh2	IDA	color key
Molecular Function	GO:0004609	phosphatidylserine decarboxylase activity	Got1	IDA	color key
Molecular Function	GO:0005515	protein binding	Glud1	IPI	color key
Cellular Component	GO:0005737	cytoplasm	Aco1	IDA	color key
Cellular Component	GO:0005829	cytosol	Aco1	IDA	color key
Cellular Component	GO:0005829	cytosol	Got1	IDA	color key
Cellular Component	GO:0005829	cytosol	Idh1	IDA	color key
Cellular Component	GO:0005743	mitochondrial inner membrane	Glud1	IDA	color key
Cellular Component	GO:0005743	mitochondrial inner membrane	Got2	IDA	color key
Cellular Component	GO:0005743	mitochondrial inner membrane	Idh2	IDA	color key
Cellular Component	GO:0005743	mitochondrial inner membrane	Mdh2	IDA	color key
Cellular Component	GO:0005743	mitochondrial inner membrane	Sdha	IDA	color key
Cellular Component	GO:0005743	mitochondrial inner membrane	Sdhb	IDA	color key
Cellular Component	GO:0005743	mitochondrial inner membrane	Suclg1	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Aco2	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Cs	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Fh1	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Glud1	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Got2	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Idh2	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Mdh2	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Sdha	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Sdhb	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Sdhc	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Sdhd	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Sucla2	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Suclg1	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Suclg2	IDA	color key
Biological Process	GO:0006532	aspartate biosynthetic process	Got1	IDA	color key
Biological Process	GO:0006532	aspartate biosynthetic process	Got2	IDA	color key
Biological Process	GO:0006879	cellular iron ion homeostasis	Aco1	IGI	color key
Biological Process	GO:0006879	cellular iron ion homeostasis	Aco1	IMP	color key
Biological Process	GO:0055089	fatty acid homeostasis	Got1	IDA	color key
Biological Process	GO:0019551	glutamate catabolic process to 2-oxoglutarate	Got1	IDA	color key
Biological Process	GO:0019551	glutamate catabolic process to 2-oxoglutarate	Got2	IDA	color key
Biological Process	GO:0019550	glutamate catabolic process to aspartate	Got1	IDA	color key
Biological Process	GO:0019550	glutamate catabolic process to aspartate	Got2	IDA	color key
Biological Process	GO:0006749	glutathione metabolic process	Idh1	IMP	color key
Biological Process	GO:0006114	glycerol biosynthetic process	Got1	IDA	color key
Biological Process	GO:0048873	homeostasis of number of cells within a tissue	Fh1	IMP	color key
Biological Process	GO:0050892	intestinal absorption	Aco1	IGI	color key
Biological Process	GO:0046676	negative regulation of insulin secretion	Glud1	IGI	color key
Biological Process	GO:0046676	negative regulation of insulin secretion	Glud1	IMP	color key
Biological Process	GO:0006107	oxaloacetate metabolic process	Got1	IDA	color key
Biological Process	GO:0006107	oxaloacetate metabolic process	Got2	IDA	color key
Biological Process	GO:0009791	post-embryonic development	Aco1	IGI	color key
Biological Process	GO:0010468	regulation of gene expression	Aco1	IGI	color key
Biological Process	GO:0006417	regulation of translation	Aco1	IMP	color key
Biological Process	GO:0006979	response to oxidative stress	Idh1	IDA	color key