Key:
hm homozygous ht heterozygous tg involves transgenes phenotype observed
cn conditional genotype  cx complex: > 1 genome feature ot other: hemizygous, indeterminate,... N normal phenotype
Genotype/
Background:
Phenotypes:
Affected Systems
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craniofacial
abnormal tooth development
abnormal dental mesenchyme morphology
abnormal secondary palate development
palatal shelf hypoplasia
abnormal palatine aponeurosis morphology
small levator veli palatini muscle
abnormal palatopharyngeus muscle morphology
small tensor veli palatini muscle
cleft palate
digestive/alimentary system
abnormal secondary palate development
palatal shelf hypoplasia
abnormal palatine aponeurosis morphology
small levator veli palatini muscle
abnormal palatopharyngeus muscle morphology
small tensor veli palatini muscle
cleft palate
embryo
abnormal dental mesenchyme morphology
growth/size/body
abnormal tooth development
abnormal dental mesenchyme morphology
abnormal secondary palate development
palatal shelf hypoplasia
abnormal palatine aponeurosis morphology
small levator veli palatini muscle
abnormal palatopharyngeus muscle morphology
small tensor veli palatini muscle
cleft palate
mortality/aging
neonatal lethality
muscle
small levator veli palatini muscle
abnormal palatopharyngeus muscle morphology
small tensor veli palatini muscle
abnormal superior pharyngeal constrictor muscle morphology
respiratory system
abnormal superior pharyngeal constrictor muscle morphology
skeleton
abnormal tooth development
abnormal dental mesenchyme morphology