| Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
  | Bamforth-Lazarus syndrome | FOXE1* | Foxe1* | 1 model | Alliance of Genome Resources | ||
| congenital hypothyroidism | TPO* | Tpo* | 1 model | Alliance of Genome Resources | |||
| congenital hypothyroidism | PAX8* | Pax8* | 3 models | Alliance of Genome Resources | |||
| congenital hypothyroidism | DUOX2* | Duox2* | 1 model | Alliance of Genome Resources | |||
| thyroid gland papillary carcinoma | BRAF* | Braf* | 2 models | Alliance of Genome Resources | |||
| thyroid hormone resistance syndrome | THRB* | Thrb* | 10 models | Alliance of Genome Resources | |||
| | congenital hypothyroidism | RUNX2 | Runx2* | 1 model | Alliance of Genome Resources | ||
| congenital hypothyroidism | SLC26A7 | Slc26a7* | 1 model | Alliance of Genome Resources | |||
| congenital hypothyroidism | TG | Tg* | 1 model | Alliance of Genome Resources | |||
| congenital hypothyroidism | TRHR | Trhr* | 1 model | Alliance of Genome Resources | |||
| congenital hypothyroidism | TSHR | Tshr* | 4 models | Alliance of Genome Resources | |||
| congenital hypothyroidism | FOXE1 | Foxe1* | 1 model | Alliance of Genome Resources | |||
| familial medullary thyroid carcinoma | PRLR | Prlr* | 1 model | Alliance of Genome Resources | |||
| thyroid gland follicular carcinoma | THRB | Thrb* | 2 models | Alliance of Genome Resources | |||
| thyroid gland follicular carcinoma | PTEN | Pten* | 3 models | Alliance of Genome Resources | |||
| thyroid gland follicular carcinoma | PRKAR1A | Prkar1a* | 2 models | Alliance of Genome Resources | |||
| thyroid hormone resistance syndrome | THRA | Thra* | 2 models | Alliance of Genome Resources | |||
| thyroid hormone resistance syndrome | NCOA1 | Ncoa1* | 1 model | Alliance of Genome Resources | |||
| | congenital hypothyroidism | SLC5A5* | Slc5a5 | Alliance of Genome Resources | |||
| congenital nongoitrous hypothyroidism 2 | PAX8* | Pax8 | Alliance of Genome Resources | ||||
| congenital nongoitrous hypothyroidism 4 | TSHB* | Tshb | Alliance of Genome Resources | ||||
| congenital nongoitrous hypothyroidism 5 | NKX2-5* | Nkx2-5 | Alliance of Genome Resources | ||||
| congenital nongoitrous hypothyroidism 6 | THRA* | Thra | Alliance of Genome Resources | ||||
| congenital nongoitrous hypothyroidism 7 | TRHR* | Trhr | Alliance of Genome Resources | ||||
| congenital nongoitrous hypothyroidism 8 | TBL1X*, TBL1Y | Tbl1x | Alliance of Genome Resources | ||||
| congenital nongoitrous hypothyroidism 9 | IRS4* | Irs4 | Alliance of Genome Resources | ||||
| dystransthyretinemic hyperthyroxinemia | TTR* | Ttr | Alliance of Genome Resources | ||||
| familial medullary thyroid carcinoma | RET* | Ret | 2 "NOT" models | Alliance of Genome Resources | |||
| goiter | SLC26A4* | Slc26a4 | Alliance of Genome Resources | ||||
| goiter | TG* | Tg | Alliance of Genome Resources | ||||
| hyperthyroidism | HLA-DQB1*, HLA-DQB2 | H2-Ab1 | Alliance of Genome Resources | ||||
| hyperthyroxinemia | ALB* | Alb | Alliance of Genome Resources | ||||
| hypothyroidism | HLA-DRB1*, HLA-DRB3, HLA-DRB4, HLA-DRB5 | H2-Eb1, H2-Eb2 | Alliance of Genome Resources | ||||
| hypothyroidism | PTPN22* | Ptpn22 | Alliance of Genome Resources | ||||
| hypothyroidism | TSHB* | Tshb | Alliance of Genome Resources | ||||
| hypothyroidism | HLA-DQB1*, HLA-DQB2 | H2-Ab1 | Alliance of Genome Resources | ||||
| multinodular goiter | DICER1* | Dicer1 | Alliance of Genome Resources | ||||
| nonautoimmune hyperthyroidism | TSHR* | Tshr | Alliance of Genome Resources | ||||
| selective pituitary thyroid hormone resistance | THRB* | Thrb | Alliance of Genome Resources | ||||
| thyroid dyshormonogenesis 1 | SLC5A5* | Slc5a5 | Alliance of Genome Resources | ||||
| thyroid dyshormonogenesis 2A | TPO* | Tpo | Alliance of Genome Resources | ||||
| thyroid dyshormonogenesis 3 | TG* | Tg | Alliance of Genome Resources | ||||
| thyroid dyshormonogenesis 4 | IYD* | Iyd | Alliance of Genome Resources | ||||
| thyroid dyshormonogenesis 5 | DUOXA2* | Duoxa2 | Alliance of Genome Resources | ||||
| thyroid dyshormonogenesis 6 | DUOX2* | Duox2 | Alliance of Genome Resources | ||||
| thyroid gland carcinoma | ATP6V0C* | Atp6v0c | Alliance of Genome Resources | ||||
| thyroid gland disease | TRU-TCA1-1* | ||||||
| thyroid gland disease | SECISBP2* | Secisbp2 | Alliance of Genome Resources | ||||
| thyroid gland disease | DIO1* | Dio1 | Alliance of Genome Resources | ||||
| thyroid gland Hurthle cell carcinoma | NDUFA13* | Ndufa13 | Alliance of Genome Resources | ||||
| thyroid gland papillary carcinoma | NKX2-1* | Nkx2-1 | Alliance of Genome Resources | ||||
| thyroid gland papillary carcinoma | MINPP1* | Minpp1 | Alliance of Genome Resources | ||||
| thyroid gland papillary carcinoma | KMT2D* | Kmt2d | Alliance of Genome Resources | ||||
| thyroid gland papillary carcinoma | HRAS* | Hras | Alliance of Genome Resources | ||||
| thyroid gland papillary carcinoma | HABP2* | Habp2 | Alliance of Genome Resources | ||||
| thyroid gland papillary carcinoma | FOXE1* | Foxe1 | Alliance of Genome Resources | ||||
| thyroid gland papillary carcinoma | ATM* | Atm | Alliance of Genome Resources | ||||
| thyroid gland papillary carcinoma | NRAS* | Nras | Alliance of Genome Resources | ||||
| thyroid gland papillary carcinoma | WDR3* | Wdr3 | Alliance of Genome Resources | ||||
| thyroid gland papillary carcinoma | TP53* | Trp53 | Alliance of Genome Resources | ||||
| thyroid gland papillary carcinoma | SRGAP1* | Srgap1 | Alliance of Genome Resources | ||||
| thyroid gland papillary carcinoma | XRCC1* | Xrcc1 | Alliance of Genome Resources | ||||
Excel File
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Transgenes and other genome features developed in mice to model this disease.
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| Disease Term | Transgenes and Other Genome Features | Mouse Models | |
| thyroid cancer | Tg(TG-TPR/NTRK1)#Rstn | 1 model | |
| thyroid gland follicular carcinoma | Tg(TG-NRAS*Q61K)#Msnt | 1 model | |
| thyroid gland papillary carcinoma | Tg(TG-TPR/NTRK1)5215Rstn | 1 model | |
| thyroid gland papillary carcinoma | Tg(tetO-BRAF*V600E)26Jaf | 1 model | |
| thyroid gland papillary carcinoma | Tg(TG-BRAF*V600E)2Jaf | 1 model | |
| thyroid gland papillary carcinoma | Tg(TG-RET/CCDC6)42Cled | 1 model | |
| thyroid gland papillary carcinoma | Tg(TG-RET/NCOA4)3209Rstn | 1 model | |
| thyroid hormone resistance syndrome | Tg(ACTB-THRB*)DSyc | 1 model | |