Key:

hm	homozygous	ht	heterozygous	tg	involves transgenes	√	phenotype observed
cn	conditional genotype	cx	complex: > 1 genome feature	ot	other: hemizygous, indeterminate,...	N	normal phenotype

Genotype/
Background:

Phenotypes:

Affected Systems	cn1	cn2	cn3	cn4
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cardiovascular system				N
cardiovascular system phenotype				N
embryo	√		√	N
embryo phenotype				N
abnormal hindlimb bud morphology			√
abnormal limb mesenchyme morphology	√
integument		N
integument phenotype		N
limbs/digits/tail	√	√	√	√
abnormal digit morphology	√
hindlimb oligodactyly			√
abnormal hindlimb zeugopod morphology			√
absent hindlimb			√
abnormal limb development		√		√
abnormal hindlimb bud morphology			√
abnormal limb mesenchyme morphology	√
mortality/aging				N
mortality/aging				N
skeleton	√		√
abnormal ischium morphology			√
absent pubis			√
abnormal cartilage morphology	√
abnormal cartilage development	√
abnormal chondrocyte differentiation	√
abnormal joint morphology	√