MGI MouseCyc MP annotations for PWY-1622

MGI MouseCyc experimental MP annotations for formaldehyde assimilation I (serine pathway)

Roles of genes might be detected in a summary/comparison table of high level MP categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";

Compare annotations to MP categories for formaldehyde assimilation I (serine pathway)

Entry indicates that gene is in this pathway.
Colored entries indicate MP annotation.

ID	Term	6430537H07Rik	Eno1	Eno2	Eno3	Glyctk	Mdh1	Mdh1b	Mdh2	Pgam1	Pgam2	Shmt1	Shmt2
MP:0005386	behavior/neurological phenotype	6430537H07Rik	Eno1	Eno2	Eno3	Glyctk	Mdh1	Mdh1b	Mdh2	Pgam1	Pgam2	Shmt1	Shmt2
MP:0005380	embryogenesis phenotype	6430537H07Rik	Eno1	Eno2	Eno3	Glyctk	Mdh1	Mdh1b	Mdh2	Pgam1	Pgam2	Shmt1	Shmt2
MP:0005378	growth/size phenotype	6430537H07Rik	Eno1	Eno2	Eno3	Glyctk	Mdh1	Mdh1b	Mdh2	Pgam1	Pgam2	Shmt1	Shmt2
MP:0005376	homeostasis/metabolism phenotype	6430537H07Rik	Eno1	Eno2	Eno3	Glyctk	Mdh1	Mdh1b	Mdh2	Pgam1	Pgam2	Shmt1	Shmt2
MP:0005374	lethality-prenatal/perinatal	6430537H07Rik	Eno1	Eno2	Eno3	Glyctk	Mdh1	Mdh1b	Mdh2	Pgam1	Pgam2	Shmt1	Shmt2
MP:0005370	liver/biliary system phenotype	6430537H07Rik	Eno1	Eno2	Eno3	Glyctk	Mdh1	Mdh1b	Mdh2	Pgam1	Pgam2	Shmt1	Shmt2
MP:0003631	nervous system phenotype	6430537H07Rik	Eno1	Eno2	Eno3	Glyctk	Mdh1	Mdh1b	Mdh2	Pgam1	Pgam2	Shmt1	Shmt2
MP:0005394	taste/olfaction phenotype	6430537H07Rik	Eno1	Eno2	Eno3	Glyctk	Mdh1	Mdh1b	Mdh2	Pgam1	Pgam2	Shmt1	Shmt2

Full set of annotations for formaldehyde assimilation I (serine pathway)

ID	Term	Mouse gene	Alleles	Background	Color Key
MP:0005311	abnormal circulating amino acid level	Shmt1	Shmt1^tm1Stov/Shmt1⁺	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0005311	abnormal circulating amino acid level	Shmt1	Shmt1^tm1Stov/Shmt1^tm1Stov	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0001469	abnormal contextual conditioning	Eno2	Eno2^tm1(DTA)Hsak/Eno2^tm1(DTA)Hsak,Tg(Nes-cre/ERT2)4Kag/0	involves: C57BL/6	color key
MP:0001454	abnormal cued conditioning behavior	Eno2	Eno2^tm1(DTA)Hsak/Eno2⁺,Gng7^{tm2(cre/PGR)Mmsh}/Gng7⁺	involves: C57BL/6	color key
MP:0000812	abnormal dentate gyrus morphology	Eno2	Eno2^tm1(DTA)Hsak/Eno2^tm1(DTA)Hsak,Tg(Nes-cre/ERT2)4Kag/0	involves: C57BL/6	color key
MP:0005584	abnormal enzyme/coenzyme activity	Mdh1	Mdh1^am1H/Mdh1⁺	involves: C3H/HeH	color key
MP:0001449	abnormal learning/ memory	Eno2	Eno2^tm1(DTA)Hsak/Eno2⁺,Gng7^{tm2(cre/PGR)Mmsh}/Gng7⁺	involves: C57BL/6	color key
MP:0000609	abnormal liver physiology	Shmt1	Shmt1^tm1.1Stov/Shmt1^tm1.1Stov	129S/SvEv-Shmt1	color key
MP:0000609	abnormal liver physiology	Shmt1	Shmt1^tm1.1Stov/Shmt1^tm1.1Stov	involves: 129S7/SvEvBrd * BALB/cJ * C57BL/6	color key
MP:0000609	abnormal liver physiology	Shmt1	Shmt1^tm1.1Stov/Shmt1⁺	129S/SvEv-Shmt1	color key
MP:0008432	abnormal long-term spatial reference memory	Eno2	Eno2^tm1(DTA)Hsak/Eno2^tm1(DTA)Hsak,Tg(Nes-cre/ERT2)4Kag/0	involves: C57BL/6	color key
MP:0008462	abnormal medium spiny neuron morphology	Eno2	Eno2^tm1(DTA)Hsak/Eno2⁺,Gng7^{tm2(cre/PGR)Mmsh}/Gng7⁺	involves: C57BL/6	color key
MP:0002804	abnormal motor learning	Eno2	Eno2^tm1(DTA)Hsak/Eno2⁺,Gng7^{tm2(cre/PGR)Mmsh}/Gng7⁺	involves: C57BL/6	color key
MP:0001984	abnormal olfaction	Eno2	Acsm4^tm1(cre)Hsak/?,Eno2^tm1(DTA)Hsak/?	involves: 129S2/SvPas * C57BL/6	color key
MP:0001460	abnormal olfactory -discrimination memory	Eno2	Acsm4^tm1(cre)Hsak/?,Eno2^tm1(DTA)Hsak/?	involves: 129S2/SvPas * C57BL/6	color key
MP:0000819	abnormal olfactory bulb morphology	Eno2	Eno2^tm1(DTA)Hsak/Eno2^tm1(DTA)Hsak,Tg(Nes-cre/ERT2)5-1Kag/0	involves: C57BL/6	color key
MP:0000819	abnormal olfactory bulb morphology	Eno2	Eno2^tm1(DTA)Hsak/Eno2^tm1(DTA)Hsak,Tg(Nes-cre/ERT2)4Kag/0	involves: C57BL/6	color key
MP:0006092	abnormal olfactory neuron morphology	Eno2	Eno2^tm1(DTA)Hsak/?,Tg(Olfr16-cre,-CFP)1Hsak/?	involves: C57BL/6	color key
MP:0006092	abnormal olfactory neuron morphology	Eno2	Acsm4^tm1(cre)Hsak/?,Eno2^tm1(DTA)Hsak/?	involves: 129S2/SvPas * C57BL/6	color key
MP:0001003	abnormal olfactory receptor morphology	Eno2	Eno2^tm1(DTA)Hsak/?,Tg(Olfr16-cre,-CFP)1Hsak/?	involves: C57BL/6	color key
MP:0001003	abnormal olfactory receptor morphology	Eno2	Acsm4^tm1(cre)Hsak/?,Eno2^tm1(DTA)Hsak/?	involves: 129S2/SvPas * C57BL/6	color key
MP:0002067	abnormal sensory capabilities/reflexes/nociception	Eno2	Acsm4^tm1(cre)Hsak/?,Eno2^tm1(DTA)Hsak/?	involves: 129S2/SvPas * C57BL/6	color key
MP:0002067	abnormal sensory capabilities/reflexes/nociception	Eno2	Eno2^tm1(DTA)Hsak/?,Tg(Olfr16-cre,-CFP)1Hsak/?	involves: C57BL/6	color key
MP:0008924	decreased granule neuron number	Eno2	Eno2^tm1(DTA)Hsak/Eno2^tm1(DTA)Hsak,Tg(Nes-cre/ERT2)4Kag/0	involves: C57BL/6	color key
MP:0008924	decreased granule neuron number	Eno2	Eno2^tm1(DTA)Hsak/Eno2^tm1(DTA)Hsak,Tg(Nes-cre/ERT2)5-1Kag/0	involves: C57BL/6	color key
MP:0008948	decreased neuron number	Eno2	Eno2^tm1(DTA)Hsak/Eno2^tm1(DTA)Hsak,Tg(Nes-cre/ERT2)4Kag/0	involves: C57BL/6	color key
MP:0008948	decreased neuron number	Eno2	Eno2^tm1(DTA)Hsak/Eno2^tm1(DTA)Hsak,Tg(Nes-cre/ERT2)5-1Kag/0	involves: C57BL/6	color key
MP:0001730	embryonic growth arrest	Eno1	Eno1^{Gt(ROSABetageo)1Ev}/Eno1^{Gt(ROSABetageo)1Ev}	involves: 129S/SvEv	color key
MP:0006205	embryonic lethality before somite formation	Eno1	Eno1^{Gt(ROSABetageo)1Ev}/Eno1^{Gt(ROSABetageo)1Ev}	involves: 129S/SvEv	color key
MP:0001399	hyperactivity	Eno2	Eno2^tm1(DTA)Hsak/Eno2⁺,Gng7^{tm2(cre/PGR)Mmsh}/Gng7⁺	involves: C57BL/6	color key
MP:0003203	increased neuron apoptosis	Eno2	Eno2^tm1(DTA)Hsak/Eno2⁺,Gng7^{tm2(cre/PGR)Mmsh}/Gng7⁺	involves: C57BL/6	color key
MP:0002080	prenatal lethality	Mdh1	Mdh1^am1H/Mdh1^am1H	involves: C3H/HeH	color key
MP:0001698	reduced embryo size	Eno1	Eno1^{Gt(ROSABetageo)1Ev}/Eno1^{Gt(ROSABetageo)1Ev}	involves: 129S/SvEv	color key