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Eno1 Gene Detail
 Symbol
Name
ID
Eno1
enolase 1, alpha non-neuron
MGI:95393

Nomenclature History
Synonyms 2-phospho-D-glycerate hydrolase, alpha-enolase, Eno-1, MBP-1
Genetic Map
Chromosome 4
79.0 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 8)

Sequence Map
Chr4:149610830-149622988 bp, + strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; hamster, Chinese; lemur, mouse; pig, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Eno1 ± 2 cM)
TreeFam: TF300391
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000010390 VEGA Gene Model | MGI Sequence Detail 12159 C57BL/6J ± Kb
transcript NM_023119 RefSeq | MGI Sequence Detail 1831 C57BL/6
polypeptide NP_075608 RefSeq | MGI Sequence Detail 434 C57BL/6
For the selected sequences
All sequences(92)
Alleles
and
phenotypes 		All alleles(58) : Gene trapped(58)
Homozygous animals exhibit growth arrest and embryonic lethality at approximately E6.5.
Polymorphisms RFLP(2) SNPs within 2kb(108 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process glycolysis, in utero embryonic development...
Component cellular_component
Function lyase activity, magnesium ion binding...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression Literature Summary: (10 records)
Data Summary: Assays (5)    Results (149)    Tissues (122)    Images (29)
Theiler Stages: 15,18,19,20,22,24,26,28
  Assay Type Assays   Results
      RNA in situ 5   149
cDNA source data(25)
External Resources: Allen Brain Atlas  GENSAT  GEO 
Molecular
reagents 		All nucleic(32) Genomic(2) cDNA(29) Other(1)
Microarray probesets(7)
Pathways
glycolysis III
gluconeogenesis
glycolysis I
glycolysis II
Other database
links
EC 4.2.1.11
Ensembl Gene Model ENSMUSG00000063524
Consensus CDS Project CCDS18971.1
Entrez Gene 13806
VEGA Gene Model OTTMUSG00000010390
International Mouse Knockout Project Status Eno1
Protein
domains
InterPro ID Description
IPR000941 Enolase
IPR020809 Enolase, conserved site
IPR020810 Enolase, C-terminal
IPR020811 Enolase, N-terminal
References
(Earliest) J:5856 D'Ancona GG et al., "Assignment of the gene for enolase to mouse chromosome 4 using somatic cell hybrids." Cytogenet Cell Genet 1977;19(1):1-6
(Latest) J:129119 Wang J et al., "HUPO BPP pilot study: a proteomics analysis of the mouse brain of different developmental stages." Proteomics 2007 Nov;7(21):4008-15
All references(38)
Other
accession IDs 		MGD-MRK-9503, MGD-MRK-9506, MGI:2143710
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
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