MGI MouseCyc MP annotations for P23-PWY

MGI MouseCyc experimental MP annotations for reductive TCA cycle I

Roles of genes might be detected in a summary/comparison table of high level MP categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";

Compare annotations to MP categories for reductive TCA cycle I

Entry indicates that gene is in this pathway.
Colored entries indicate MP annotation.

ID	Term	Acly	Aco1	Aco2	Fh1	Mdh1	Mdh1b	Mdh2	Sucla2	Suclg1	Suclg2
MP:0005376	homeostasis/metabolism phenotype	Acly	Aco1	Aco2	Fh1	Mdh1	Mdh1b	Mdh2	Sucla2	Suclg1	Suclg2
MP:0005374	lethality-prenatal/perinatal	Acly	Aco1	Aco2	Fh1	Mdh1	Mdh1b	Mdh2	Sucla2	Suclg1	Suclg2
MP:0002873	normal phenotype	Acly	Aco1	Aco2	Fh1	Mdh1	Mdh1b	Mdh2	Sucla2	Suclg1	Suclg2
MP:0005367	renal/urinary system phenotype	Acly	Aco1	Aco2	Fh1	Mdh1	Mdh1b	Mdh2	Sucla2	Suclg1	Suclg2

Full set of annotations for reductive TCA cycle I

ID	Term	Mouse gene	Alleles	Background	Color Key
MP:0005584	abnormal enzyme/coenzyme activity	Fh1	Fh1^tm1Pjp/Fh1^tm1Pjp,Tg(Cdh16-cre)91Igr/0	involves: 129X1/SvJ * ICR	color key
MP:0005584	abnormal enzyme/coenzyme activity	Mdh1	Mdh1^am1H/Mdh1⁺	involves: C3H/HeH	color key
MP:0005637	abnormal iron homeostasis	Aco1	Aco1^tm1Roua/Aco1^tm1Roua	involves: 129/Sv * C57BL/6	color key
MP:0002703	abnormal renal tubule morphology	Fh1	Fh1^tm1Pjp/Fh1^tm1Pjp,Tg(Cdh16-cre)91Igr/0	involves: 129X1/SvJ * ICR	color key
MP:0006205	embryonic lethality before somite formation	Fh1	Fh1^tm1.1Pjp/Fh1^tm1.1Pjp	involves: 129X1/SvJ * BALB/c * C57BL/6	color key
MP:0006206	embryonic lethality before turning of embryo	Acly	Acly^{Gt(NPX098)Byg}/Acly^{Gt(NPX098)Byg}	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0005264	glomerulosclerosis	Fh1	Fh1^tm1Pjp/Fh1^tm1Pjp,Tg(Cdh16-cre)91Igr/0	involves: 129X1/SvJ * ICR	color key
MP:0000519	hydronephrosis	Fh1	Fh1^tm1Pjp/Fh1^tm1Pjp,Tg(Cdh16-cre)91Igr/0	involves: 129X1/SvJ * ICR	color key
MP:0000522	kidney cortex cysts	Fh1	Fh1^tm1Pjp/Fh1^tm1Pjp,Tg(Cdh16-cre)91Igr/0	involves: 129X1/SvJ * ICR	color key
MP:0003675	kidney cysts	Fh1	Fh1^tm1Pjp/Fh1^tm1Pjp,Tg(Cdh16-cre)91Igr/0	involves: 129X1/SvJ * ICR	color key
MP:0003606	kidney failure	Fh1	Fh1^tm1Pjp/Fh1^tm1Pjp,Tg(Cdh16-cre)91Igr/0	involves: 129X1/SvJ * ICR	color key
MP:0006208	lethality throughout fetal growth and development	Aco1	Aco1^tm1Mwh/Aco1^tm1Mwh	involves: 129P2/OlaHsd * C57BL/6J	color key
MP:0002169	no abnormal phenotype detected	Aco1	Aco1^tm1.1Mwh/Aco1^tm1.1Mwh	involves: 129P2/OlaHsd * C57BL/6 * SJL	color key
MP:0002169	no abnormal phenotype detected	Aco1	Aco1^tm1.2Mwh/Aco1^tm1.2Mwh	involves: 129P2/OlaHsd * C57BL/6J	color key
MP:0001762	polyuria	Fh1	Fh1^tm1Pjp/Fh1^tm1Pjp,Tg(Cdh16-cre)91Igr/0	involves: 129X1/SvJ * ICR	color key
MP:0002080	prenatal lethality	Mdh1	Mdh1^am1H/Mdh1^am1H	involves: C3H/HeH	color key