MGI MouseCyc MP annotations for ILEU-DEG2-PWY

MGI MouseCyc experimental MP annotations for isoleucine degradation III

Roles of genes might be detected in a summary/comparison table of high level MP categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";

Compare annotations to MP categories for isoleucine degradation III

Entry indicates that gene is in this pathway.
Colored entries indicate MP annotation.

ID	Term	Acat1	Acat2	Bcat1	Bcat2	Echs1	Ehhadh	Hadha	Hsd17b10	Mcee	Mut	Pcca	Pccb
MP:0005375	adipose tissue phenotype	Acat1	Acat2	Bcat1	Bcat2	Echs1	Ehhadh	Hadha	Hsd17b10	Mcee	Mut	Pcca	Pccb
MP:0005386	behavior/neurological phenotype	Acat1	Acat2	Bcat1	Bcat2	Echs1	Ehhadh	Hadha	Hsd17b10	Mcee	Mut	Pcca	Pccb
MP:0005385	cardiovascular system phenotype	Acat1	Acat2	Bcat1	Bcat2	Echs1	Ehhadh	Hadha	Hsd17b10	Mcee	Mut	Pcca	Pccb
MP:0005384	cellular phenotype	Acat1	Acat2	Bcat1	Bcat2	Echs1	Ehhadh	Hadha	Hsd17b10	Mcee	Mut	Pcca	Pccb
MP:0005380	embryogenesis phenotype	Acat1	Acat2	Bcat1	Bcat2	Echs1	Ehhadh	Hadha	Hsd17b10	Mcee	Mut	Pcca	Pccb
MP:0005378	growth/size phenotype	Acat1	Acat2	Bcat1	Bcat2	Echs1	Ehhadh	Hadha	Hsd17b10	Mcee	Mut	Pcca	Pccb
MP:0005376	homeostasis/metabolism phenotype	Acat1	Acat2	Bcat1	Bcat2	Echs1	Ehhadh	Hadha	Hsd17b10	Mcee	Mut	Pcca	Pccb
MP:0005373	lethality-postnatal	Acat1	Acat2	Bcat1	Bcat2	Echs1	Ehhadh	Hadha	Hsd17b10	Mcee	Mut	Pcca	Pccb
MP:0005374	lethality-prenatal/perinatal	Acat1	Acat2	Bcat1	Bcat2	Echs1	Ehhadh	Hadha	Hsd17b10	Mcee	Mut	Pcca	Pccb
MP:0005372	life span-post-weaning/aging	Acat1	Acat2	Bcat1	Bcat2	Echs1	Ehhadh	Hadha	Hsd17b10	Mcee	Mut	Pcca	Pccb
MP:0005370	liver/biliary system phenotype	Acat1	Acat2	Bcat1	Bcat2	Echs1	Ehhadh	Hadha	Hsd17b10	Mcee	Mut	Pcca	Pccb
MP:0005369	muscle phenotype	Acat1	Acat2	Bcat1	Bcat2	Echs1	Ehhadh	Hadha	Hsd17b10	Mcee	Mut	Pcca	Pccb
MP:0005367	renal/urinary system phenotype	Acat1	Acat2	Bcat1	Bcat2	Echs1	Ehhadh	Hadha	Hsd17b10	Mcee	Mut	Pcca	Pccb
MP:0005388	respiratory system phenotype	Acat1	Acat2	Bcat1	Bcat2	Echs1	Ehhadh	Hadha	Hsd17b10	Mcee	Mut	Pcca	Pccb
MP:0005393	skin/coat/nails phenotype	Acat1	Acat2	Bcat1	Bcat2	Echs1	Ehhadh	Hadha	Hsd17b10	Mcee	Mut	Pcca	Pccb

Full set of annotations for isoleucine degradation III

ID	Term	Mouse gene	Alleles	Background	Color Key
MP:0004774	abnormal bile salt level	Ehhadh	Ehhadh^tm1Jkr/Ehhadh^tm1Jkr,Hsd17b4^tm1Baes/Hsd17b4^tm1Baes	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J	color key
MP:0000179	abnormal blood chemistry	Hadha	Hadha^tm1Jib/Hadha^tm1Jib	involves: 129X1/SvJ * NIH Black Swiss	color key
MP:0000179	abnormal blood chemistry	Mut	Mut^tm1Pai/Mut^tm1Pai	involves: 129S1/Sv * C57BL/6	color key
MP:0001951	abnormal breathing	Mut	Mut^tm1Pai/Mut^tm1Pai	involves: 129S1/Sv * C57BL/6	color key
MP:0005329	abnormal cardiac muscle morphology	Hadha	Hadha^tm1Jib/Hadha^tm1Jib	involves: 129X1/SvJ * NIH Black Swiss	color key
MP:0000358	abnormal cell content/ morphology	Ehhadh	Ehhadh^tm1Jkr/Ehhadh^tm1Jkr	involves: 129P2/OlaHsd * C57BL/6J	color key
MP:0000358	abnormal cell content/ morphology	Ehhadh	Ehhadh^tm1Jkr/Ehhadh^tm1Jkr,Hsd17b4^tm1Baes/Hsd17b4^tm1Baes	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J	color key
MP:0005311	abnormal circulating amino acid level	Bcat2	Bcat2^tm1.2Clyn/Bcat2^tm1.2Clyn	involves: BALB/cJ * C57BL/6J * C57BL/6N	color key
MP:0005311	abnormal circulating amino acid level	Bcat2	Bcat2^m1Ytc/Bcat2^m1Ytc	C57BL/6J	color key
MP:0001570	abnormal circulating enzyme level	Hadha	Hadha^tm1Jib/Hadha^tm1Jib	involves: 129X1/SvJ * NIH Black Swiss	color key
MP:0002279	abnormal diaphragm morphology	Hadha	Hadha^tm1Jib/Hadha^tm1Jib	involves: 129X1/SvJ * NIH Black Swiss	color key
MP:0001432	abnormal food preference	Bcat2	Bcat2^tm1.2Clyn/Bcat2^tm1.2Clyn	involves: BALB/cJ * C57BL/6J * C57BL/6N	color key
MP:0002078	abnormal glucose homeostasis	Bcat2	Bcat2^tm1.2Clyn/Bcat2^tm1.2Clyn	involves: BALB/cJ * C57BL/6J * C57BL/6N	color key
MP:0000607	abnormal hepatocyte morphology	Hadha	Hadha^tm1Jib/Hadha^tm1Jib	involves: 129X1/SvJ * NIH Black Swiss	color key
MP:0000607	abnormal hepatocyte morphology	Hadha	Hadha^tm1Jib/Hadha⁺	involves: 129X1/SvJ * NIH Black Swiss	color key
MP:0001764	abnormal homeostasis	Bcat2	Bcat2^tm1.2Clyn/Bcat2^tm1.2Clyn	involves: BALB/cJ * C57BL/6J * C57BL/6N	color key
MP:0003953	abnormal hormone level	Bcat2	Bcat2^tm1.2Clyn/Bcat2^tm1.2Clyn	involves: BALB/cJ * C57BL/6J * C57BL/6N	color key
MP:0002118	abnormal lipid homeostasis	Bcat2	Bcat2^tm1.2Clyn/Bcat2^tm1.2Clyn	involves: BALB/cJ * C57BL/6J * C57BL/6N	color key
MP:0002118	abnormal lipid homeostasis	Ehhadh	Ehhadh^tm1Jkr/Ehhadh^tm1Jkr,Hsd17b4^tm1Baes/Hsd17b4^tm1Baes	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J	color key
MP:0002118	abnormal lipid homeostasis	Ehhadh	Ehhadh^tm1Jkr/Ehhadh^tm1Jkr	involves: 129P2/OlaHsd * C57BL/6J	color key
MP:0001547	abnormal lipid level	Ehhadh	Ehhadh^tm1Jkr/Ehhadh^tm1Jkr,Hsd17b4^tm1Baes/Hsd17b4^tm1Baes	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J	color key
MP:0006035	abnormal mitochondrial morphology	Ehhadh	Ehhadh^tm1Jkr/Ehhadh^tm1Jkr,Hsd17b4^tm1Baes/Hsd17b4^tm1Baes	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J	color key
MP:0001388	abnormal stationary movement	Pcca	Pcca^tm1Tmiy/Pcca^tm1Tmiy	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0001436	abnormal suckling behavior	Ehhadh	Ehhadh^tm1Jkr/Ehhadh^tm1Jkr,Hsd17b4^tm1Baes/Hsd17b4^tm1Baes	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J	color key
MP:0001436	abnormal suckling behavior	Mut	Mut^tm1Pai/Mut^tm1Pai	involves: 129S1/Sv * C57BL/6	color key
MP:0001436	abnormal suckling behavior	Pcca	Pcca^tm1Tmiy/Pcca^tm1Tmiy	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0001757	abnormal urine chemistry	Bcat2	Bcat2^tm1.2Clyn/Bcat2^tm1.2Clyn	involves: BALB/cJ * C57BL/6J * C57BL/6N	color key
MP:0001757	abnormal urine chemistry	Hadha	Hadha^tm1Jib/Hadha^tm1Jib	involves: 129X1/SvJ * NIH Black Swiss	color key
MP:0001757	abnormal urine chemistry	Mut	Mut^tm1Pai/Mut^tm1Pai	involves: 129S1/Sv * C57BL/6	color key
MP:0000414	alopecia	Bcat2	Bcat2^m1Ytc/Bcat2^m1Ytc	C57BL/6J	color key
MP:0003624	anuria	Pcca	Pcca^tm1Tmiy/Pcca^tm1Tmiy	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0005156	bradykinesia	Bcat2	Bcat2^m1Ytc/Bcat2^m1Ytc	C57BL/6J	color key
MP:0005156	bradykinesia	Mut	Mut^tm1Pai/Mut^tm1Pai	involves: 129S1/Sv * C57BL/6	color key
MP:0004893	decreased adiponectin level	Bcat2	Bcat2^tm1.2Clyn/Bcat2^tm1.2Clyn	involves: BALB/cJ * C57BL/6J * C57BL/6N	color key
MP:0001262	decreased body weight	Bcat2	Bcat2^tm1.2Clyn/Bcat2^tm1.2Clyn	involves: BALB/cJ * C57BL/6J * C57BL/6N	color key
MP:0003978	decreased circulating carnitine level	Hadha	Hadha^tm1Jib/Hadha^tm1Jib	involves: 129X1/SvJ * NIH Black Swiss	color key
MP:0002702	decreased circulating free fatty acid level	Bcat2	Bcat2^tm1.2Clyn/Bcat2^tm1.2Clyn	involves: BALB/cJ * C57BL/6J * C57BL/6N	color key
MP:0005560	decreased circulating glucose level	Bcat2	Bcat2^tm1.2Clyn/Bcat2^tm1.2Clyn	involves: BALB/cJ * C57BL/6J * C57BL/6N	color key
MP:0002727	decreased circulating insulin level	Bcat2	Bcat2^tm1.2Clyn/Bcat2^tm1.2Clyn	involves: BALB/cJ * C57BL/6J * C57BL/6N	color key
MP:0003458	decreased circulating ketone body level	Bcat2	Bcat2^tm1.2Clyn/Bcat2^tm1.2Clyn	involves: BALB/cJ * C57BL/6J * C57BL/6N	color key
MP:0005668	decreased circulating leptin level	Bcat2	Bcat2^tm1.2Clyn/Bcat2^tm1.2Clyn	involves: BALB/cJ * C57BL/6J * C57BL/6N	color key
MP:0009289	decreased epididymal fat pad weight	Bcat2	Bcat2^tm1.2Clyn/Bcat2^tm1.2Clyn	involves: BALB/cJ * C57BL/6J * C57BL/6N	color key
MP:0005282	decreased fatty acid level	Ehhadh	Ehhadh^tm1Jkr/Ehhadh^tm1Jkr,Hsd17b4^tm1Baes/Hsd17b4^tm1Baes	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J	color key
MP:0005439	decreased glycogen level	Pcca	Pcca^tm1Tmiy/Pcca^tm1Tmiy	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0005459	decreased percent body fat	Bcat2	Bcat2^tm1.2Clyn/Bcat2^tm1.2Clyn	involves: BALB/cJ * C57BL/6J * C57BL/6N	color key
MP:0001429	dehydration	Pcca	Pcca^tm1Tmiy/Pcca^tm1Tmiy	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0002705	dilated renal tubules	Pcca	Pcca^tm1Tmiy/Pcca^tm1Tmiy	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0003984	embryonic growth retardation	Hadha	Hadha^tm1Jib/Hadha^tm1Jib	involves: 129X1/SvJ * NIH Black Swiss	color key
MP:0003068	enlarged kidney	Bcat2	Bcat2^tm1.2Clyn/Bcat2^tm1.2Clyn	involves: BALB/cJ * C57BL/6J * C57BL/6N	color key
MP:0000599	enlarged liver	Hadha	Hadha^tm1Jib/Hadha^tm1Jib	involves: 129X1/SvJ * NIH Black Swiss	color key
MP:0002628	hepatic steatosis	Ehhadh	Ehhadh^tm1Jkr/Ehhadh^tm1Jkr,Hsd17b4^tm1Baes/Hsd17b4^tm1Baes	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J	color key
MP:0002628	hepatic steatosis	Hadha	Hadha^tm1Jib/Hadha^tm1Jib	involves: 129X1/SvJ * NIH Black Swiss	color key
MP:0002628	hepatic steatosis	Hadha	Hadha^tm1Jib/Hadha⁺	involves: 129X1/SvJ * NIH Black Swiss	color key
MP:0002628	hepatic steatosis	Pcca	Pcca^tm1Tmiy/Pcca^tm1Tmiy	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0001402	hypoactivity	Ehhadh	Ehhadh^tm1Jkr/Ehhadh^tm1Jkr,Hsd17b4^tm1Baes/Hsd17b4^tm1Baes	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J	color key
MP:0000189	hypoglycemia	Hadha	Hadha^tm1Jib/Hadha^tm1Jib	involves: 129X1/SvJ * NIH Black Swiss	color key
MP:0004144	hypotonia	Ehhadh	Ehhadh^tm1Jkr/Ehhadh^tm1Jkr,Hsd17b4^tm1Baes/Hsd17b4^tm1Baes	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J	color key
MP:0005292	improved glucose tolerance	Bcat2	Bcat2^tm1.2Clyn/Bcat2^tm1.2Clyn	involves: BALB/cJ * C57BL/6J * C57BL/6N	color key
MP:0005565	increased blood urea nitrogen level	Hadha	Hadha^tm1Jib/Hadha^tm1Jib	involves: 129X1/SvJ * NIH Black Swiss	color key
MP:0005533	increased body temperature	Bcat2	Bcat2^tm1.2Clyn/Bcat2^tm1.2Clyn	involves: BALB/cJ * C57BL/6J * C57BL/6N	color key
MP:0005344	increased circulating bilirubin level	Hadha	Hadha^tm1Jib/Hadha^tm1Jib	involves: 129X1/SvJ * NIH Black Swiss	color key
MP:0003979	increased circulating carnitine level	Hadha	Hadha^tm1Jib/Hadha^tm1Jib	involves: 129X1/SvJ * NIH Black Swiss	color key
MP:0001554	increased circulating free fatty acid level	Hadha	Hadha^tm1Jib/Hadha⁺	involves: 129X1/SvJ * NIH Black Swiss	color key
MP:0002079	increased circulating insulin level	Hadha	Hadha^tm1Jib/Hadha⁺	involves: 129X1/SvJ * NIH Black Swiss	color key
MP:0003909	increased eating behavior	Bcat2	Bcat2^tm1.2Clyn/Bcat2^tm1.2Clyn	involves: BALB/cJ * C57BL/6J * C57BL/6N	color key
MP:0004889	increased energy expenditure	Bcat2	Bcat2^tm1.2Clyn/Bcat2^tm1.2Clyn	involves: BALB/cJ * C57BL/6J * C57BL/6N	color key
MP:0002891	increased insulin sensitivity	Bcat2	Bcat2^tm1.2Clyn/Bcat2^tm1.2Clyn	involves: BALB/cJ * C57BL/6J * C57BL/6N	color key
MP:0003960	increased lean body mass	Bcat2	Bcat2^tm1.2Clyn/Bcat2^tm1.2Clyn	involves: BALB/cJ * C57BL/6J * C57BL/6N	color key
MP:0005659	increased resistance to diet-induced obesity	Bcat2	Bcat2^tm1.2Clyn/Bcat2^tm1.2Clyn	involves: BALB/cJ * C57BL/6J * C57BL/6N	color key
MP:0005331	insulin resistance	Hadha	Hadha^tm1Jib/Hadha⁺	involves: 129X1/SvJ * NIH Black Swiss	color key
MP:0002893	ketoaciduria	Bcat2	Bcat2^m1Ytc/Bcat2^m1Ytc	C57BL/6J	color key
MP:0002893	ketoaciduria	Pcca	Pcca^tm1Tmiy/Pcca^tm1Tmiy	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0002058	neonatal lethality	Ehhadh	Ehhadh^tm1Jkr/Ehhadh^tm1Jkr,Hsd17b4^tm1Baes/Hsd17b4^tm1Baes	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J	color key
MP:0002058	neonatal lethality	Hadha	Hadha^tm1Jib/Hadha^tm1Jib	involves: 129X1/SvJ * NIH Black Swiss	color key
MP:0002058	neonatal lethality	Mut	Mut^tm1Pai/Mut^tm1Pai	involves: 129S1/Sv * C57BL/6	color key
MP:0001762	polyuria	Bcat2	Bcat2^tm1.2Clyn/Bcat2^tm1.2Clyn	involves: BALB/cJ * C57BL/6J * C57BL/6N	color key
MP:0001732	postnatal growth retardation	Bcat2	Bcat2^m1Ytc/Bcat2^m1Ytc	C57BL/6J	color key
MP:0001732	postnatal growth retardation	Ehhadh	Ehhadh^tm1Jkr/Ehhadh^tm1Jkr,Hsd17b4^tm1Baes/Hsd17b4^tm1Baes	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J	color key
MP:0002082	postnatal lethality	Ehhadh	Ehhadh^tm1Jkr/Ehhadh^tm1Jkr,Hsd17b4^tm1Baes/Hsd17b4^tm1Baes	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J	color key
MP:0002082	postnatal lethality	Pcca	Pcca^tm1Tmiy/Pcca^tm1Tmiy	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0002083	premature death	Bcat2	Bcat2^m1Ytc/Bcat2^m1Ytc	C57BL/6J	color key
MP:0000746	weakness	Bcat2	Bcat2^m1Ytc/Bcat2^m1Ytc	C57BL/6J	color key