MGI MouseCyc all GO annotations for P23-PWY

MGI MouseCyc all GO annotations for P23-PWY: reductive TCA cycle I

Roles of genes might be detected in a summary/comparison table of high level GO categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";
Black arrows indicate "regulates";
Green arrows indicate "positively_regulates";
Red arrows indicate "negatively_regulates"

Compare annotations to GO categories for P23-PWY: reductive TCA cycle I

Entry indicates that gene is in this pathway.
Colored entries indicate GO annotation.

Category	ID	Term	Acly	Aco1	Aco2	Fh1	Mdh1	Mdh1b	Mdh2	Sucla2	Suclg1	Suclg2
Molecular Function	GO:0005488	binding	Acly	Aco1	Aco2	Fh1	Mdh1	Mdh1b	Mdh2	Sucla2	Suclg1	Suclg2
Molecular Function	GO:0003824	catalytic activity	Acly	Aco1	Aco2	Fh1	Mdh1	Mdh1b	Mdh2	Sucla2	Suclg1	Suclg2
Cellular Component	GO:0005623	cell	Acly	Aco1	Aco2	Fh1	Mdh1	Mdh1b	Mdh2	Sucla2	Suclg1	Suclg2
Cellular Component	GO:0044464	cell part	Acly	Aco1	Aco2	Fh1	Mdh1	Mdh1b	Mdh2	Sucla2	Suclg1	Suclg2
Cellular Component	GO:0031975	envelope	Acly	Aco1	Aco2	Fh1	Mdh1	Mdh1b	Mdh2	Sucla2	Suclg1	Suclg2
Cellular Component	GO:0032991	macromolecular complex	Acly	Aco1	Aco2	Fh1	Mdh1	Mdh1b	Mdh2	Sucla2	Suclg1	Suclg2
Cellular Component	GO:0043226	organelle	Acly	Aco1	Aco2	Fh1	Mdh1	Mdh1b	Mdh2	Sucla2	Suclg1	Suclg2
Cellular Component	GO:0044422	organelle part	Acly	Aco1	Aco2	Fh1	Mdh1	Mdh1b	Mdh2	Sucla2	Suclg1	Suclg2
Biological Process	GO:0065007	biological regulation	Acly	Aco1	Aco2	Fh1	Mdh1	Mdh1b	Mdh2	Sucla2	Suclg1	Suclg2
Biological Process	GO:0009987	cellular process	Acly	Aco1	Aco2	Fh1	Mdh1	Mdh1b	Mdh2	Sucla2	Suclg1	Suclg2
Biological Process	GO:0032502	developmental process	Acly	Aco1	Aco2	Fh1	Mdh1	Mdh1b	Mdh2	Sucla2	Suclg1	Suclg2
Biological Process	GO:0008152	metabolic process	Acly	Aco1	Aco2	Fh1	Mdh1	Mdh1b	Mdh2	Sucla2	Suclg1	Suclg2
Biological Process	GO:0032501	multicellular organismal process	Acly	Aco1	Aco2	Fh1	Mdh1	Mdh1b	Mdh2	Sucla2	Suclg1	Suclg2
Biological Process	GO:0050789	regulation of biological process	Acly	Aco1	Aco2	Fh1	Mdh1	Mdh1b	Mdh2	Sucla2	Suclg1	Suclg2

Full set of annotations for P23-PWY: reductive TCA cycle I

Category	ID	Term	Mouse gene	Evidence	Color Key
Molecular Function	GO:0051539	4 iron, 4 sulfur cluster binding	Aco1	IEA	color key
Molecular Function	GO:0051539	4 iron, 4 sulfur cluster binding	Aco2	IEA	color key
Molecular Function	GO:0003994	aconitate hydratase activity	Aco1	IDA	color key
Molecular Function	GO:0003994	aconitate hydratase activity	Aco2	IDA	color key
Molecular Function	GO:0005524	ATP binding	Acly	IEA	color key
Molecular Function	GO:0005524	ATP binding	Sucla2	IEA	color key
Molecular Function	GO:0005524	ATP binding	Suclg2	IEA	color key
Molecular Function	GO:0003878	ATP citrate synthase activity	Acly	TAS	color key
Molecular Function	GO:0003878	ATP citrate synthase activity	Suclg1	IEA	color key
Molecular Function	GO:0005488	binding	Acly	IEA	color key
Molecular Function	GO:0005488	binding	Mdh1	IEA	color key
Molecular Function	GO:0005488	binding	Mdh1b	IEA	color key
Molecular Function	GO:0005488	binding	Mdh2	IEA	color key
Molecular Function	GO:0005488	binding	Suclg1	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Acly	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Fh1	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Mdh1	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Mdh1b	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Mdh2	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Sucla2	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Suclg1	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Suclg2	IEA	color key
Molecular Function	GO:0004333	fumarate hydratase activity	Fh1	IEA	color key
Molecular Function	GO:0005525	GTP binding	Suclg1	IEA	color key
Molecular Function	GO:0005506	iron ion binding	Aco1	IEA	color key
Molecular Function	GO:0005506	iron ion binding	Aco2	ISO	color key
Molecular Function	GO:0030350	iron-responsive element binding	Aco1	IDA	color key
Molecular Function	GO:0051536	iron-sulfur cluster binding	Aco1	IEA	color key
Molecular Function	GO:0051536	iron-sulfur cluster binding	Aco2	IEA	color key
Molecular Function	GO:0030060	L-malate dehydrogenase activity	Mdh1	IEA	color key
Molecular Function	GO:0030060	L-malate dehydrogenase activity	Mdh2	IDA	color key
Molecular Function	GO:0016874	ligase activity	Sucla2	IEA	color key
Molecular Function	GO:0016874	ligase activity	Suclg1	IEA	color key
Molecular Function	GO:0016874	ligase activity	Suclg2	IEA	color key
Molecular Function	GO:0016829	lyase activity	Acly	IEA	color key
Molecular Function	GO:0016829	lyase activity	Aco1	IEA	color key
Molecular Function	GO:0016829	lyase activity	Aco2	IEA	color key
Molecular Function	GO:0016829	lyase activity	Fh1	IEA	color key
Molecular Function	GO:0000287	magnesium ion binding	Acly	IEA	color key
Molecular Function	GO:0016615	malate dehydrogenase activity	Mdh1	IEA	color key
Molecular Function	GO:0016615	malate dehydrogenase activity	Mdh1b	IEA	color key
Molecular Function	GO:0016615	malate dehydrogenase activity	Mdh2	ISA	color key
Molecular Function	GO:0046872	metal ion binding	Acly	IEA	color key
Molecular Function	GO:0046872	metal ion binding	Aco1	IEA	color key
Molecular Function	GO:0046872	metal ion binding	Aco2	IEA	color key
Molecular Function	GO:0000166	nucleotide binding	Acly	IEA	color key
Molecular Function	GO:0000166	nucleotide binding	Suclg1	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Mdh1	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Mdh1b	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Mdh2	IEA	color key
Molecular Function	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	Mdh1	IEA	color key
Molecular Function	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	Mdh2	IEA	color key
Molecular Function	GO:0005515	protein binding	Acly	IPI	color key
Molecular Function	GO:0005515	protein binding	Mdh2	ISA	color key
Molecular Function	GO:0003723	RNA binding	Aco1	IEA	color key
Molecular Function	GO:0004775	succinate-CoA ligase (ADP-forming) activity	Acly	IEA	color key
Molecular Function	GO:0004775	succinate-CoA ligase (ADP-forming) activity	Sucla2	IEA	color key
Molecular Function	GO:0004775	succinate-CoA ligase (ADP-forming) activity	Suclg1	IEA	color key
Molecular Function	GO:0004776	succinate-CoA ligase (GDP-forming) activity	Suclg1	IEA	color key
Molecular Function	GO:0004776	succinate-CoA ligase (GDP-forming) activity	Suclg2	IEA	color key
Molecular Function	GO:0004774	succinate-CoA ligase activity	Sucla2	ISS	color key
Molecular Function	GO:0004777	succinate-semialdehyde dehydrogenase activity	Suclg2	ISA	color key
Molecular Function	GO:0016740	transferase activity	Acly	IEA	color key
Molecular Function	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer	Acly	IEA	color key
Cellular Component	GO:0005737	cytoplasm	Acly	IEA	color key
Cellular Component	GO:0005737	cytoplasm	Aco1	IDA	color key
Cellular Component	GO:0005737	cytoplasm	Fh1	IEA	color key
Cellular Component	GO:0005737	cytoplasm	Mdh1	IEA	color key
Cellular Component	GO:0005829	cytosol	Aco1	IDA	color key
Cellular Component	GO:0005829	cytosol	Mdh1	ISO	color key
Cellular Component	GO:0005783	endoplasmic reticulum	Aco1	ISO	color key
Cellular Component	GO:0005794	Golgi apparatus	Aco1	ISO	color key
Cellular Component	GO:0005622	intracellular	Acly	TAS	color key
Cellular Component	GO:0005743	mitochondrial inner membrane	Mdh2	IDA	color key
Cellular Component	GO:0005743	mitochondrial inner membrane	Suclg1	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Aco2	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Fh1	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Mdh2	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Mdh2	ISA	color key
Cellular Component	GO:0005739	mitochondrion	Sucla2	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Suclg1	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Suclg2	IDA	color key
Cellular Component	GO:0045239	tricarboxylic acid cycle enzyme complex	Fh1	IEA	color key
Biological Process	GO:0006085	acetyl-CoA biosynthetic process	Acly	TAS	color key
Biological Process	GO:0005975	carbohydrate metabolic process	Mdh1	IEA	color key
Biological Process	GO:0005975	carbohydrate metabolic process	Mdh1b	IEA	color key
Biological Process	GO:0005975	carbohydrate metabolic process	Mdh2	IEA	color key
Biological Process	GO:0044262	cellular carbohydrate metabolic process	Acly	IEA	color key
Biological Process	GO:0044262	cellular carbohydrate metabolic process	Mdh1	IEA	color key
Biological Process	GO:0044262	cellular carbohydrate metabolic process	Mdh2	IEA	color key
Biological Process	GO:0006879	cellular iron ion homeostasis	Aco1	IGI	color key
Biological Process	GO:0006879	cellular iron ion homeostasis	Aco1	IMP	color key
Biological Process	GO:0006101	citrate metabolic process	Aco2	ISO	color key
Biological Process	GO:0006106	fumarate metabolic process	Fh1	IEA	color key
Biological Process	GO:0006096	glycolysis	Mdh1	IEA	color key
Biological Process	GO:0006096	glycolysis	Mdh2	IEA	color key
Biological Process	GO:0048873	homeostasis of number of cells within a tissue	Fh1	IMP	color key
Biological Process	GO:0050892	intestinal absorption	Aco1	IGI	color key
Biological Process	GO:0008610	lipid biosynthetic process	Acly	IEA	color key
Biological Process	GO:0006108	malate metabolic process	Mdh1	IEA	color key
Biological Process	GO:0006108	malate metabolic process	Mdh1b	IEA	color key
Biological Process	GO:0006108	malate metabolic process	Mdh2	ISA	color key
Biological Process	GO:0008152	metabolic process	Acly	IEA	color key
Biological Process	GO:0008152	metabolic process	Aco1	IEA	color key
Biological Process	GO:0008152	metabolic process	Aco2	IEA	color key
Biological Process	GO:0008152	metabolic process	Mdh1	IEA	color key
Biological Process	GO:0008152	metabolic process	Mdh1b	IEA	color key
Biological Process	GO:0008152	metabolic process	Mdh2	IEA	color key
Biological Process	GO:0008152	metabolic process	Sucla2	IEA	color key
Biological Process	GO:0008152	metabolic process	Suclg1	IEA	color key
Biological Process	GO:0008152	metabolic process	Suclg2	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Mdh1	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Mdh1b	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Mdh2	IEA	color key
Biological Process	GO:0009791	post-embryonic development	Aco1	IGI	color key
Biological Process	GO:0010468	regulation of gene expression	Aco1	IGI	color key
Biological Process	GO:0006417	regulation of translation	Aco1	IMP	color key
Biological Process	GO:0006099	tricarboxylic acid cycle	Aco1	IEA	color key
Biological Process	GO:0006099	tricarboxylic acid cycle	Aco2	ISO	color key
Biological Process	GO:0006099	tricarboxylic acid cycle	Fh1	IEA	color key
Biological Process	GO:0006099	tricarboxylic acid cycle	Mdh1	IEA	color key
Biological Process	GO:0006099	tricarboxylic acid cycle	Mdh1b	IEA	color key
Biological Process	GO:0006099	tricarboxylic acid cycle	Mdh2	IEA	color key
Biological Process	GO:0006099	tricarboxylic acid cycle	Sucla2	IEA	color key
Biological Process	GO:0006099	tricarboxylic acid cycle	Suclg1	IEA	color key
Biological Process	GO:0006099	tricarboxylic acid cycle	Suclg2	IEA	color key