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All mouse models of Leigh disease with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | Leigh disease | \Ndufs4tm1.1Rpa/\Ndufs4tm1.1Rpa | B6.129S4-Ndufs4tm1.1Rpa | J:190475 | View | |||
| Leigh disease |
\Ndufs4tm1Rpa/\Ndufs4tm1Rpa \Tg(Nes-cre)1Kln/0 |
B6.Cg-Tg(Nes-cre)1Kln Ndufs4tm1Rpa | J:190475 | View | ||||
| Leigh disease |
\Ndufs4tm1Rpa/\Ndufs4tm1Rpa \Tg(Nes-cre)1Kln/0 |
involves: 129S4/SvJaeSor * C57BL/6 * SJL | J:161393 | View | ||||
| Leigh disease | \Surf1tm1Zev/\Surf1tm1Zev | involves: 129S7/SvEvBrd * C57BL/6J * DBA/2 | J:81773 | View | ||||
| | Leigh disease | \Parltm1.1Bdes/\Parltm1.1Bdes | involves: 129P2/OlaHsd | J:269785 | View | |||
| Leigh disease |
\Parltm1Bdes/\Parltm1Bdes \Tg(Nes-cre)1Kln/0 |
involves: 129P2/OlaHsd * C57BL/6 * SJL | J:269785 | View | ||||
| Leigh disease |
\Sdhctm1c(EUCOMM)Wtsi/\Sdhctm1c(EUCOMM)Wtsi \Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn/\Gt(ROSA)26Sor+ |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6N | J:284745 | View | ||||
| Leigh disease | \Sod2tm1Cje/\Sod2tm1Cje | involves: C57BL/6J | J:45913 | View | ||||