| hm | homozygous | ht | heterozygous | tg | involves transgenes | √ | phenotype observed |
| cn | conditional genotype | cx | complex: > 1 genome feature | ot | other: hemizygous, indeterminate,... | N | normal phenotype |
Background:
| Affected Systems | |
|---|---|
behavior/neurological
|
√ |
|
lethargy
|
√ |
|
hunched posture
|
√ |
|
cellular
|
√ |
|
decreased NK cell degranulation
|
√ |
|
growth/size/body
|
√ |
|
weight loss
|
√ |
|
hematopoietic system
|
√ |
|
decreased NK cell degranulation
|
√ |
|
decreased erythrocyte cell number
|
√ |
|
thrombocytopenia
|
√ |
|
decreased leukocyte cell number
|
√ |
|
decreased neutrophil cell number
|
√ |
|
pancytopenia
|
√ |
|
abnormal cytotoxic T cell physiology
|
√ |
|
decreased cytotoxic T cell cytolysis
|
√ |
|
homeostasis/metabolism
|
√ |
|
increased circulating interferon-gamma level
|
√ |
|
increased circulating interleukin-1 beta level
|
√ |
|
increased circulating interleukin-6 level
|
√ |
|
increased circulating tumor necrosis factor level
|
√ |
|
increased circulating aspartate transaminase level
|
√ |
|
increased circulating lactate dehydrogenase level
|
√ |
|
decreased body temperature
|
√ |
|
immune system
|
√ |
|
decreased NK cell degranulation
|
√ |
|
decreased leukocyte cell number
|
√ |
|
decreased neutrophil cell number
|
√ |
|
abnormal cytotoxic T cell physiology
|
√ |
|
decreased cytotoxic T cell cytolysis
|
√ |
|
increased circulating interferon-gamma level
|
√ |
|
increased circulating interleukin-1 beta level
|
√ |
|
increased circulating interleukin-6 level
|
√ |
|
increased circulating tumor necrosis factor level
|
√ |
|
increased susceptibility to Riboviria infection
|
√ |
