Key:

hm	homozygous	ht	heterozygous	tg	involves transgenes	√	phenotype observed
cn	conditional genotype	cx	complex: > 1 genome feature	ot	other: hemizygous, indeterminate,...	N	normal phenotype

Genotype/
Background:

Phenotypes:

Affected Systems	hm1	hm2	ht3	ht4
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behavior/neurological	√	√	√	√
abnormal behavior		√		√
enhanced behavioral response to anesthetic		√
increased anxiety-related response		√
abnormal reflex		√
abnormal pilomotor reflex		√		√
abnormal pinna reflex			√	√
absent pinna reflex			√	√
decreased startle reflex	√	√		√
tremors		√		√
impaired coordination		√
hunched posture		√		√
growth/size/body		√		√
decreased body weight		√		√
hearing/vestibular/ear	√	√	√	√
hearing/vestibular/ear phenotype	N	N	N	N
abnormal auditory brainstem response waveform shape		√
increased or absent threshold for auditory brainstem response	√	√	√	√
impaired hearing		√		√
mortality/aging		N
mortality/aging		N
nervous system		√
decreased Purkinje cell number		√
small cerebellum		√