Key:
hm homozygous ht heterozygous tg involves transgenes phenotype observed
cn conditional genotype  cx complex: > 1 genome feature ot other: hemizygous, indeterminate,... N normal phenotype
Genotype/
Background:
Phenotypes:
Affected Systems
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cardiovascular system
atherosclerotic lesions
increased susceptibility to atherosclerosis
abnormal blood vessel elastic tissue morphology
homeostasis/metabolism
increased circulating cholesterol level
increased circulating LDL cholesterol level
increased circulating VLDL cholesterol level
increased circulating triglyceride level