Origins of Inbred Mice

TABLE 1. Inbred Strains Used in the Production of Congenic Resistant (CR) Strains


Strain^a	Short Symbol	Genotype^{b, c}

A/WySn	A	(17) H-2^a Tla^a Pgk-2^a Apl^b
AKR/J	AKR	(17) H-2^k Tla^b Pgk-2^b Apl^b Ly-2^a
BALB/c	C	(2) H-3^c Ir-2^b H-13^{not a or b} A (7) c Hbb^d H-1^b (9) Thy-1^b Fv-2^s H-7^b (17) H-2^d Tla^c Pgk-2^a Apl^b H-9^b
CBA	CBA	(19) Ly-1^b
CE/J	CE	(2) H-3^b Ir-2^b H-13^b A^w (7) H-4^{not a or b} c^e Hbb^s H-1^{a, b, or c}
C3H/HeDiSn	C3H	(2) H-3^b Ir-2^? H-13^c A (7) H-4^a C Hbb^d H-1^a (17) H-2^k Tla^b Pgk-2^b Apl^b
C57BL/6By	B6	Same as C57BL/10Sn except H-9^{not a or b}, a difference at an H locus on chromosome 4, and an Ea difference.
C57BL/10Sn	B10	(2) H-3^a Ir-2^a We Un H-13^a a (6) Ly-2,3^b (7) P H-4^a C Hbb^s H-1^c (9) Thy-1^b Fv-2^r H-7^a (17) H-2^b Tla^b Pgk-2^a Apl^b Ea-2^b Ea-7^b Hc¹ H-8^a H-9^a H-10^a H-11^a H-12^a Mlv-1^b
DA/HuSn	DA	(17) H-2^qp Tla^b Pgk-2^b Apl^?
DBA/1	D1	(17) H-2^q Tla^b Pgk-2^a Apl^?
DBA/2	D2	(7) Hbb^d H-1^a (17) H-2^d Tla^c Pgk-2^a Apl^b Hc⁰ H-8^b H-11^? Mlv-1^a
FS/Ei	FS	(7) p H-4^? c^ch sh-1 Hbb^d H-1^? fr
HTG/SFSN	HTG	(17) H-2^g Tla^b Pgk^? Apl^?
JK/Sf	JK	(17) H-2^j Tla^b Pgk-2^? Apl^?
KR/Di	KR	(2) H-3^d Ir-2^? H-13^c A
LG/Ckc	LG/CKC	(17) H-2^ar
LP	LP	(2) H-3^b Ir-2^? H-13^b A^w (17) H-2^{b(or bc)} Tla^c Pgk-2^c Apl^b
P/Sn	P	(7) p H-4^? C Hbb^d H-1^? (17) H-2^p Tla^? Pgk-2^a Apl^b
PA/Re	B6-pa	(2) pa H-3^? H-13^?
PL/J	PL	(6) Ly-2,3^a (9) Thy-1^a (17) H-2^u Tla^a Pgk-2^a Apl^b
RIII	RIII	(17) H-2^r Tla^? Pgk-2^b Apl^? E-a²
SEC	SEC	(7) H-4^? c^ch Hbb^s H-1^{not a, b, or c}
SM/J	SM	(7) H-4^? C Hbb^s H-1^{not a, b, or c} (17) H-2^v Tla^b Pgk-2^a Apl^a
ST/bJ	ST	(17) H-2^k Tla^b Pgk-2^b Apl^b
UW/Le	UW	(2) H-3^b Ir-2^? we un H-13^a a^t
WB/Re	WB	(7) H-4^{not a or b} C Hbb^d H-1^a (17) H-2^ja Tla^b Pgk-2^a Apl^b
129	129	(2) H-3^b Ir-2^? H-13^b A^w (7) p H-4^b c Hbb^d H-1^b (17) H-2^bc Tla^c Pgk-2^c Apl^b H-10^b H-11^b H-12^b Ea-7^a

Legend to Table 1 ^aThe strains listed are those inbred strains which entered, either as first or second parent, into the production of the congenic strains shown in Tables 2, 3, 4, and 5. In the case of some of the early strains, especially those in Table 2, the subtrain used is unknown and is therefore not indicated. Where more than one substrain is used, as in the case of C57BL/6, the currently most relevant is shown. ^bThe loci listed for each inbred strain are, with the exception of a few linked loci, those at which differences occur between one or more congenics and the inbred strain. Chromosome numbers, where known, are indicated in parentheses. Genes closest to the centromere are given at the left of each group of linked genes. Loci whose relative positions are undetermined are bracketed. The references from which information concerning genotype have been taken are: 34 (information re H-1, H-3, H-13, strain KR), 35 ( H-3), 39 ( Ir-2), 41 ( Tla), 43 ( Pgk-2), 44 (linkage of Fv-2 and H-7), 58 (non-H-2 alleles), 59 (non-H-2 alleles), 60 ( a, c, Hbb, Hc, H-2, p), 62 (strains FS and UW), 63 (does BALB/c have fifth Tla allele?), 64 ( Apl), 65 (Ea difference between B6 and B10). ^cThe Pgk-2 allele of strain 129 differs in different sublines. The allele in the subline which we have used appears to have been Pgk-2^c.

REFERENCES

34. Graff, R.J., and Bailey, D.W. (1973). Transplant. Rev. 15: 26.
See also MGI.

35. Graff, R.J., Brown, D., and Snell, G.D. (1973). Transplant. Rev. 15: 299.

39. Gasser, D.L. (1976). Immunogenetics 3: 271.
See also MGI.

41. Flaherty, L., Sullivan, K., and Zimmerman, D. (1977). J. Immunol. 119: 571.
See also MGI.

43. Eicher, E.M., Cherry, M., and Flaherty, L. (1978). Mol. Gen. Genet. 158: 225.
See also MGI.

44. Bailey, D.W., and Lilly, F. (1978). Personal communication.

58. Graff, R.J., and Snell, G.D. (1969). Transplantation 8: 861.

59. Graff, R.J., Polinsky, S.L., and Snell, G.D. (1971). Transplantation 11: 56.
See also PubMed.

60. Snell, G.D., and Cherry, M. (1972). In Viruses and Host Genome in Oncogenesis (P. Emmelot and P. Bentvetzen, eds.), p. 221. North-Holland Publ. Amsterdam.

62. Lane, P.W. (1974). Lists of Mutations and Mutant Stocks of the Mouse. Mimeographed, The Jackson Laboratory, Bar Harbor.

63. Snell, G.D., Dausset, J., and Nathenson, S. (1976). Histocompatibility. Academic Press, New York.
See also MGI.

64. Lally, P.A., and Shows, F.B. (1977). Genetics 87: 305.

65. Cherry, M., Bailey, D.W., and Snell, G.D. (1978). In Origins of Inbred Mice (H.C. Morse III, ed.). Academic Press, New York.