Collaborators and Large-scale Data Providers:

GXD uses the Mouse Developmental Anatomy Ontology, developed in collaboration with EMAP to describe expression patterns in standardized ways.  GXD also provides its RNA in situ and Immunohistochemistry data to EMAGE, so that the data can be spatially mapped.  The ultimate goal of our collaboration is to provide the scientific community with integrated access to text-based and graphical expression data via the Mouse Gene Expression Information Resource.

  • EMAP (Edinburgh Mouse Atlas Project) and EMAGE (Edinburgh Mouse Atlas Gene Expression Database)

We have incorporated data from several large scale expression databases into GXD. Database entries in GXD link to the corresponding entries at the providers' websites. In this way, users can take advantage of GXD's data integration and querying capabilities while having easy access to additional resources at the providers' sites.

We have also incorporated directly submitted data from the following major studies:

  • Shimogori et al. (2010) Nat Neurosci, 13, 767-775. They used in situ hybridization to examine the expression of genes in the developing hypothalamus. These data can be viewed at J:157819.
  • Guo et al. (2010) Dev Cell 18, 675-685. They used real time PCR to study transcription factor dynamics in the preimplantation embryo. These data can be viewed at J:140465.
  • Gray et al. (2004) Science 306, 2255-2257.  They used in situ hybridization to examine the expression of putative transcription factors in the developing mouse nervous system.  These data can be viewed at J:91257.
  • Blackshaw et al. (2004) PLoS Biol 2, e247.  They used in situ hybridization to examine the expression of genes in the developing mouse retina.  These data can be viewed at J:93300.
  • Gitton et al. (2002) Nature 420, 586-590.  They used in situ hybridization and RT-PCR to examine the expression of human chromosome 21 orthologues in the mouse.  These data can be viewed at J:80501.
  • Reymond et al. (2002) Nature 420, 582-586.  They used in situ hybridization and RT- RT-PCR to examine the expression of human chromosome 21 orthologues in the mouse.  These data can be viewed at J:80502.
  • Freeman et al. (1998) MGI Direct Data Submission.  They used RT-PCR to examine the expression of genes in the mouse.  These data can be viewed at J:46439.