MGI MouseCyc MP annotations for PWY6666-2

MGI MouseCyc experimental MP annotations for dopamine degradation

Roles of genes might be detected in a summary/comparison table of high level MP categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";

Compare annotations to MP categories for dopamine degradation

Entry indicates that gene is in this pathway.
Colored entries indicate MP annotation.

ID	Term	Aldh2	Comt1	Comtd1	Maoa	Maob	Sult1a1
MP:0005386	behavior/neurological phenotype	Aldh2	Comt1	Comtd1	Maoa	Maob	Sult1a1
MP:0005384	cellular phenotype	Aldh2	Comt1	Comtd1	Maoa	Maob	Sult1a1
MP:0005377	hearing/vestibular/ear phenotype	Aldh2	Comt1	Comtd1	Maoa	Maob	Sult1a1
MP:0005376	homeostasis/metabolism phenotype	Aldh2	Comt1	Comtd1	Maoa	Maob	Sult1a1
MP:0003631	nervous system phenotype	Aldh2	Comt1	Comtd1	Maoa	Maob	Sult1a1
MP:0005367	renal/urinary system phenotype	Aldh2	Comt1	Comtd1	Maoa	Maob	Sult1a1

Full set of annotations for dopamine degradation

ID	Term	Mouse gene	Alleles	Background	Color Key
MP:0004924	abnormal behavior	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/Y	involves: C3H/HeJ	color key
MP:0004924	abnormal behavior	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/?	involves: C3H/HeJ	color key
MP:0000788	abnormal cerebral cortex morphology	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/Y	involves: C3H/HeJ	color key
MP:0000788	abnormal cerebral cortex morphology	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/?	involves: C3H/HeJ	color key
MP:0005418	abnormal circulating hormone level	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/?	involves: C3H/HeJ	color key
MP:0001431	abnormal eating behavior	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/Y	involves: C3H/HeJ	color key
MP:0001431	abnormal eating behavior	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/?	involves: C3H/HeJ	color key
MP:0005584	abnormal enzyme/coenzyme activity	Aldh2	Aldh2^tm1Kaw/Aldh2^tm1Kaw	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0001440	abnormal grooming behavior	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/Y	involves: C3H/HeJ	color key
MP:0001440	abnormal grooming behavior	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/?	involves: C3H/HeJ	color key
MP:0001516	abnormal motor coordination/ balance	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/Y	involves: C3H/HeJ	color key
MP:0001516	abnormal motor coordination/ balance	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/?	involves: C3H/HeJ	color key
MP:0000937	abnormal motor neuron morphology	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/?	involves: C3H/HeJ	color key
MP:0002272	abnormal nervous system electrophysiology	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/?	involves: C3H/HeJ	color key
MP:0003964	abnormal noradrenaline level	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/Y	involves: C3H/HeJ	color key
MP:0003964	abnormal noradrenaline level	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/?	involves: C3H/HeJ	color key
MP:0005322	abnormal serotonin level	Maoa	Maoa^K284stop/Y,Maob^tm1Shih/Y	either: (involves: 129S/SvEv) or (involves: 129S4/SvJae)	color key
MP:0005322	abnormal serotonin level	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/Y	involves: C3H/HeJ	color key
MP:0005322	abnormal serotonin level	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/?	involves: C3H/HeJ	color key
MP:0005322	abnormal serotonin level	Maob	Maoa^K284stop/Y,Maob^tm1Shih/Y	either: (involves: 129S/SvEv) or (involves: 129S4/SvJae)	color key
MP:0002566	abnormal sexual interaction	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/Y	involves: C3H/HeJ	color key
MP:0001501	abnormal sleep pattern	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/Y	involves: C3H/HeJ	color key
MP:0001501	abnormal sleep pattern	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/?	involves: C3H/HeJ	color key
MP:0001360	abnormal social investigation	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/Y	involves: C3H/HeJ	color key
MP:0002557	abnormal social/conspecific interaction	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/Y	involves: C3H/HeJ	color key
MP:0002557	abnormal social/conspecific interaction	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/?	involves: C3H/HeJ	color key
MP:0001757	abnormal urine chemistry	Maob	Maob^tm1Shih/Maob^tm1Shih	either: (involves: 129S/SvEv) or (involves: 129S4/SvJae)	color key
MP:0001417	decreased exploration in new environment	Maoa	Maoa^K284stop/Y,Maob^tm1Shih/Y	either: (involves: 129S/SvEv) or (involves: 129S4/SvJae)	color key
MP:0001417	decreased exploration in new environment	Maob	Maoa^K284stop/Y,Maob^tm1Shih/Y	either: (involves: 129S/SvEv) or (involves: 129S4/SvJae)	color key
MP:0006041	decreased mitochondrial oxidation	Aldh2	Aldh2^tm1Kaw/Aldh2^tm1Kaw	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0008236	decreased susceptibility to neuronal excitotoxicity	Maob	Maob^tm1Shih/Maob^tm1Shih	either: (involves: 129S/SvEv) or (involves: 129S4/SvJae)	color key
MP:0003360	depression-related behavior	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/Y	involves: C3H/HeJ	color key
MP:0003360	depression-related behavior	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/?	involves: C3H/HeJ	color key
MP:0001410	head bobbing	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/Y	involves: C3H/HeJ	color key
MP:0001410	head bobbing	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/?	involves: C3H/HeJ	color key
MP:0001505	hunched posture	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/Y	involves: C3H/HeJ	color key
MP:0001505	hunched posture	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/?	involves: C3H/HeJ	color key
MP:0001399	hyperactivity	Maob	Maob^tm1Shih/Maob^tm1Shih	either: (involves: 129S/SvEv) or (involves: 129S4/SvJae)	color key
MP:0001400	hyperresponsive	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/Y	involves: C3H/HeJ	color key
MP:0001400	hyperresponsive	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/?	involves: C3H/HeJ	color key
MP:0001402	hypoactivity	Maoa	Maoa^K284stop/Y	129S6/SvEvTac-Maoa	color key
MP:0001525	impaired balance	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/Y	involves: C3H/HeJ	color key
MP:0001525	impaired balance	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/?	involves: C3H/HeJ	color key
MP:0001523	impaired righting response	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/Y	involves: C3H/HeJ	color key
MP:0001523	impaired righting response	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/?	involves: C3H/HeJ	color key
MP:0001357	increased aggression toward humans	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/Y	involves: C3H/HeJ	color key
MP:0001357	increased aggression toward humans	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/?	involves: C3H/HeJ	color key
MP:0001353	increased aggression toward other mice	Maoa	Maoa^K284stop/Y,Maob^tm1Shih/Y	either: (involves: 129S/SvEv) or (involves: 129S4/SvJae)	color key
MP:0001353	increased aggression toward other mice	Maob	Maoa^K284stop/Y,Maob^tm1Shih/Y	either: (involves: 129S/SvEv) or (involves: 129S4/SvJae)	color key
MP:0001354	increased aggression towards males	Comt1	Comt1^tm1Kara/Comt1⁺	involves: 129S4/SvJaeSor	color key
MP:0001354	increased aggression towards males	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/Y	involves: C3H/HeJ	color key
MP:0001354	increased aggression towards males	Maoa	Maoa^K284stop/Y	129S6/SvEvTac-Maoa	color key
MP:0001363	increased anxiety-related response	Comt1	Comt1^tm1Kara/Comt1^tm1Kara	involves: 129S4/SvJaeSor	color key
MP:0001363	increased anxiety-related response	Maoa	Maoa^K284stop/Y,Maob^tm1Shih/Y	either: (involves: 129S/SvEv) or (involves: 129S4/SvJae)	color key
MP:0001363	increased anxiety-related response	Maob	Maoa^K284stop/Y,Maob^tm1Shih/Y	either: (involves: 129S/SvEv) or (involves: 129S4/SvJae)	color key
MP:0001906	increased dopamine level	Comt1	Comt1^tm1Kara/Comt1^tm1Kara	involves: 129S4/SvJaeSor	color key
MP:0001906	increased dopamine level	Maoa	Maoa^K284stop/Y,Maob^tm1Shih/Y	either: (involves: 129S/SvEv) or (involves: 129S4/SvJae)	color key
MP:0001906	increased dopamine level	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/Y	involves: C3H/HeJ	color key
MP:0001906	increased dopamine level	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/?	involves: C3H/HeJ	color key
MP:0001906	increased dopamine level	Maob	Maoa^K284stop/Y,Maob^tm1Shih/Y	either: (involves: 129S/SvEv) or (involves: 129S4/SvJae)	color key
MP:0003459	increased fear-related response	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/Y	involves: C3H/HeJ	color key
MP:0003459	increased fear-related response	Maoa	Maoa^{Tg(H2-IFNB)8Seif}/?	involves: C3H/HeJ	color key