MGI MouseCyc MP annotations for PWY-5743

MGI MouseCyc experimental MP annotations for 3-hydroxypropionate cycle

Roles of genes might be detected in a summary/comparison table of high level MP categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";

Compare annotations to MP categories for 3-hydroxypropionate cycle

Entry indicates that gene is in this pathway.
Colored entries indicate MP annotation.

ID	Term	Acaca	Acacb	Echs1	Ehhadh	Mcee	Mut	Pcca	Pccb
MP:0005375	adipose tissue phenotype	Acaca	Acacb	Echs1	Ehhadh	Mcee	Mut	Pcca	Pccb
MP:0005386	behavior/neurological phenotype	Acaca	Acacb	Echs1	Ehhadh	Mcee	Mut	Pcca	Pccb
MP:0005384	cellular phenotype	Acaca	Acacb	Echs1	Ehhadh	Mcee	Mut	Pcca	Pccb
MP:0005380	embryogenesis phenotype	Acaca	Acacb	Echs1	Ehhadh	Mcee	Mut	Pcca	Pccb
MP:0005378	growth/size phenotype	Acaca	Acacb	Echs1	Ehhadh	Mcee	Mut	Pcca	Pccb
MP:0005376	homeostasis/metabolism phenotype	Acaca	Acacb	Echs1	Ehhadh	Mcee	Mut	Pcca	Pccb
MP:0005373	lethality-postnatal	Acaca	Acacb	Echs1	Ehhadh	Mcee	Mut	Pcca	Pccb
MP:0005374	lethality-prenatal/perinatal	Acaca	Acacb	Echs1	Ehhadh	Mcee	Mut	Pcca	Pccb
MP:0005370	liver/biliary system phenotype	Acaca	Acacb	Echs1	Ehhadh	Mcee	Mut	Pcca	Pccb
MP:0005369	muscle phenotype	Acaca	Acacb	Echs1	Ehhadh	Mcee	Mut	Pcca	Pccb
MP:0005367	renal/urinary system phenotype	Acaca	Acacb	Echs1	Ehhadh	Mcee	Mut	Pcca	Pccb
MP:0005388	respiratory system phenotype	Acaca	Acacb	Echs1	Ehhadh	Mcee	Mut	Pcca	Pccb

Full set of annotations for 3-hydroxypropionate cycle

ID	Term	Mouse gene	Alleles	Background	Color Key
MP:0004774	abnormal bile salt level	Ehhadh	Ehhadh^tm1Jkr/Ehhadh^tm1Jkr,Hsd17b4^tm1Baes/Hsd17b4^tm1Baes	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J	color key
MP:0000179	abnormal blood chemistry	Mut	Mut^tm1Pai/Mut^tm1Pai	involves: 129S1/Sv * C57BL/6	color key
MP:0001951	abnormal breathing	Mut	Mut^tm1Pai/Mut^tm1Pai	involves: 129S1/Sv * C57BL/6	color key
MP:0000358	abnormal cell content/ morphology	Ehhadh	Ehhadh^tm1Jkr/Ehhadh^tm1Jkr	involves: 129P2/OlaHsd * C57BL/6J	color key
MP:0000358	abnormal cell content/ morphology	Ehhadh	Ehhadh^tm1Jkr/Ehhadh^tm1Jkr,Hsd17b4^tm1Baes/Hsd17b4^tm1Baes	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J	color key
MP:0005450	abnormal energy expenditure	Acacb	Acacb^tm1Sjw/Acacb^tm1Sjw	Not Specified	color key
MP:0005319	abnormal enzyme/ coenzyme level	Acacb	Acacb^tm1Sjw/Acacb^tm1Sjw	Not Specified	color key
MP:0005584	abnormal enzyme/coenzyme activity	Acaca	Acaca^tm2Sjw/Acaca^tm2Sjw,Tg(Alb-cre)21Mgn/0	involves: 129S7/SvEvBrd * C57BL/6J * FVB	color key
MP:0002078	abnormal glucose homeostasis	Acaca	Acaca^tm2Sjw/Acaca^tm2Sjw,Tg(Alb-cre)21Mgn/0	involves: 129S7/SvEvBrd * C57BL/6J * FVB	color key
MP:0002118	abnormal lipid homeostasis	Acaca	Acaca^tm1Jkus/Acaca^tm1Jkus,Tg(Fabp1-cre)1Mmt/0	involves: 129X1/SvJ * C57BL/6J * SJL	color key
MP:0002118	abnormal lipid homeostasis	Acacb	Acacb^tm1Sjw/Acacb^tm1Sjw	Not Specified	color key
MP:0002118	abnormal lipid homeostasis	Ehhadh	Ehhadh^tm1Jkr/Ehhadh^tm1Jkr	involves: 129P2/OlaHsd * C57BL/6J	color key
MP:0002118	abnormal lipid homeostasis	Ehhadh	Ehhadh^tm1Jkr/Ehhadh^tm1Jkr,Hsd17b4^tm1Baes/Hsd17b4^tm1Baes	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J	color key
MP:0001547	abnormal lipid level	Acaca	Acaca^tm2Sjw/Acaca^tm2Sjw,Tg(Alb-cre)21Mgn/0	involves: 129S7/SvEvBrd * C57BL/6J * FVB	color key
MP:0001547	abnormal lipid level	Ehhadh	Ehhadh^tm1Jkr/Ehhadh^tm1Jkr,Hsd17b4^tm1Baes/Hsd17b4^tm1Baes	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J	color key
MP:0000609	abnormal liver physiology	Acaca	Acaca^tm2Sjw/Acaca^tm2Sjw,Tg(Alb-cre)21Mgn/0	involves: 129S7/SvEvBrd * C57BL/6J * FVB	color key
MP:0006035	abnormal mitochondrial morphology	Ehhadh	Ehhadh^tm1Jkr/Ehhadh^tm1Jkr,Hsd17b4^tm1Baes/Hsd17b4^tm1Baes	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J	color key
MP:0001388	abnormal stationary movement	Pcca	Pcca^tm1Tmiy/Pcca^tm1Tmiy	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0001436	abnormal suckling behavior	Ehhadh	Ehhadh^tm1Jkr/Ehhadh^tm1Jkr,Hsd17b4^tm1Baes/Hsd17b4^tm1Baes	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J	color key
MP:0001436	abnormal suckling behavior	Mut	Mut^tm1Pai/Mut^tm1Pai	involves: 129S1/Sv * C57BL/6	color key
MP:0001436	abnormal suckling behavior	Pcca	Pcca^tm1Tmiy/Pcca^tm1Tmiy	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0001757	abnormal urine chemistry	Mut	Mut^tm1Pai/Mut^tm1Pai	involves: 129S1/Sv * C57BL/6	color key
MP:0003624	anuria	Pcca	Pcca^tm1Tmiy/Pcca^tm1Tmiy	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0005156	bradykinesia	Mut	Mut^tm1Pai/Mut^tm1Pai	involves: 129S1/Sv * C57BL/6	color key
MP:0005454	decreased adipose tissue amount	Acacb	Acacb^tm1Sjw/Acacb^tm1Sjw	Not Specified	color key
MP:0001262	decreased body weight	Acacb	Acacb^tm1Sjw/Acacb^tm1Sjw	Not Specified	color key
MP:0002702	decreased circulating free fatty acid level	Acaca	Acaca^tm2Sjw/Acaca^tm2Sjw,Tg(Alb-cre)21Mgn/0	involves: 129S7/SvEvBrd * C57BL/6J * FVB	color key
MP:0003458	decreased circulating ketone body level	Acaca	Acaca^tm2Sjw/Acaca^tm2Sjw,Tg(Alb-cre)21Mgn/0	involves: 129S7/SvEvBrd * C57BL/6J * FVB	color key
MP:0005668	decreased circulating leptin level	Acacb	Acacb^tm1Sjw/Acacb^tm1Sjw	Not Specified	color key
MP:0005282	decreased fatty acid level	Acaca	Acaca^tm2Sjw/Acaca^tm2Sjw,Tg(Alb-cre)21Mgn/0	involves: 129S7/SvEvBrd * C57BL/6J * FVB	color key
MP:0005282	decreased fatty acid level	Acacb	Acacb^tm1Sjw/Acacb^tm1Sjw	Not Specified	color key
MP:0005282	decreased fatty acid level	Ehhadh	Ehhadh^tm1Jkr/Ehhadh^tm1Jkr,Hsd17b4^tm1Baes/Hsd17b4^tm1Baes	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J	color key
MP:0005439	decreased glycogen level	Acacb	Acacb^tm1Sjw/Acacb^tm1Sjw	Not Specified	color key
MP:0005439	decreased glycogen level	Pcca	Pcca^tm1Tmiy/Pcca^tm1Tmiy	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0008844	decreased subcutaneous adipose tissue amount	Acacb	Acacb^tm1Sjw/Acacb^tm1Sjw	Not Specified	color key
MP:0005318	decreased triglyceride level	Acaca	Acaca^tm2Sjw/Acaca^tm2Sjw,Tg(Alb-cre)21Mgn/0	involves: 129S7/SvEvBrd * C57BL/6J * FVB	color key
MP:0005318	decreased triglyceride level	Acaca	Acaca^tm1Jkus/Acaca^tm1Jkus,Tg(Fabp1-cre)1Mmt/0	involves: 129X1/SvJ * C57BL/6J * SJL	color key
MP:0001783	decreased white adipose tissue amount	Acacb	Acacb^tm1Sjw/Acacb^tm1Sjw	Not Specified	color key
MP:0001429	dehydration	Pcca	Pcca^tm1Tmiy/Pcca^tm1Tmiy	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0002705	dilated renal tubules	Pcca	Pcca^tm1Tmiy/Pcca^tm1Tmiy	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0001730	embryonic growth arrest	Acaca	Acaca^tm1Sjw/Acaca^tm1Sjw	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0003984	embryonic growth retardation	Acaca	Acaca^tm1.1Jkus/Acaca^tm1.1Jkus	involves: 129X1/SvJ * C57BL/6J	color key
MP:0006206	embryonic lethality before turning of embryo	Acaca	Acaca^tm1Sjw/Acaca^tm1Sjw	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0006207	embryonic lethality during organogenesis	Acaca	Acaca^tm1.1Jkus/Acaca^tm1.1Jkus	involves: 129X1/SvJ * C57BL/6J	color key
MP:0002628	hepatic steatosis	Ehhadh	Ehhadh^tm1Jkr/Ehhadh^tm1Jkr,Hsd17b4^tm1Baes/Hsd17b4^tm1Baes	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J	color key
MP:0002628	hepatic steatosis	Pcca	Pcca^tm1Tmiy/Pcca^tm1Tmiy	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0001559	hyperglycemia	Acaca	Acaca^tm2Sjw/Acaca^tm2Sjw,Tg(Alb-cre)21Mgn/0	involves: 129S7/SvEvBrd * C57BL/6J * FVB	color key
MP:0001402	hypoactivity	Ehhadh	Ehhadh^tm1Jkr/Ehhadh^tm1Jkr,Hsd17b4^tm1Baes/Hsd17b4^tm1Baes	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J	color key
MP:0000189	hypoglycemia	Acacb	Acacb^tm1Sjw/Acacb^tm1Sjw	Not Specified	color key
MP:0004144	hypotonia	Ehhadh	Ehhadh^tm1Jkr/Ehhadh^tm1Jkr,Hsd17b4^tm1Baes/Hsd17b4^tm1Baes	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J	color key
MP:0005343	increased circulating aspartate transaminase level	Acaca	Acaca^tm1Jkus/Acaca^tm1Jkus,Tg(Fabp1-cre)1Mmt/0	involves: 129X1/SvJ * C57BL/6J * SJL	color key
MP:0001554	increased circulating free fatty acid level	Acaca	Acaca^tm2Sjw/Acaca^tm2Sjw,Tg(Alb-cre)21Mgn/0	involves: 129S7/SvEvBrd * C57BL/6J * FVB	color key
MP:0002079	increased circulating insulin level	Acaca	Acaca^tm2Sjw/Acaca^tm2Sjw,Tg(Alb-cre)21Mgn/0	involves: 129S7/SvEvBrd * C57BL/6J * FVB	color key
MP:0002575	increased circulating ketone body level	Acacb	Acacb^tm1Sjw/Acacb^tm1Sjw	Not Specified	color key
MP:0001552	increased circulating triglyceride level	Acacb	Acacb^tm1Sjw/Acacb^tm1Sjw	Not Specified	color key
MP:0006040	increased mitochondrial oxidation	Acacb	Acacb^tm1Sjw/Acacb^tm1Sjw	Not Specified	color key
MP:0002310	increased resistance to hepatic steatosis	Acaca	Acaca^tm2Sjw/Acaca^tm2Sjw,Tg(Alb-cre)21Mgn/0	involves: 129S7/SvEvBrd * C57BL/6J * FVB	color key
MP:0002893	ketoaciduria	Pcca	Pcca^tm1Tmiy/Pcca^tm1Tmiy	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0002058	neonatal lethality	Ehhadh	Ehhadh^tm1Jkr/Ehhadh^tm1Jkr,Hsd17b4^tm1Baes/Hsd17b4^tm1Baes	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J	color key
MP:0002058	neonatal lethality	Mut	Mut^tm1Pai/Mut^tm1Pai	involves: 129S1/Sv * C57BL/6	color key
MP:0001433	polyphagia	Acacb	Acacb^tm1Sjw/Acacb^tm1Sjw	Not Specified	color key
MP:0001732	postnatal growth retardation	Ehhadh	Ehhadh^tm1Jkr/Ehhadh^tm1Jkr,Hsd17b4^tm1Baes/Hsd17b4^tm1Baes	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J	color key
MP:0002082	postnatal lethality	Ehhadh	Ehhadh^tm1Jkr/Ehhadh^tm1Jkr,Hsd17b4^tm1Baes/Hsd17b4^tm1Baes	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J	color key
MP:0002082	postnatal lethality	Pcca	Pcca^tm1Tmiy/Pcca^tm1Tmiy	involves: 129P2/OlaHsd * C57BL/6	color key