MGI MouseCyc MP annotations for PWY-5690

MGI MouseCyc experimental MP annotations for TCA cycle variation III (eukaryotic)

Roles of genes might be detected in a summary/comparison table of high level MP categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";

Compare annotations to MP categories for TCA cycle variation III (eukaryotic)

Entry indicates that gene is in this pathway.
Colored entries indicate MP annotation.

ID	Term	4933405O20Rik	Aco1	Aco2	Cs	Csl	Fh1	Idh3a	Idh3b	Idh3g	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
MP:0005385	cardiovascular system phenotype	4933405O20Rik	Aco1	Aco2	Cs	Csl	Fh1	Idh3a	Idh3b	Idh3g	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
MP:0005384	cellular phenotype	4933405O20Rik	Aco1	Aco2	Cs	Csl	Fh1	Idh3a	Idh3b	Idh3g	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
MP:0005380	embryogenesis phenotype	4933405O20Rik	Aco1	Aco2	Cs	Csl	Fh1	Idh3a	Idh3b	Idh3g	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
MP:0005376	homeostasis/metabolism phenotype	4933405O20Rik	Aco1	Aco2	Cs	Csl	Fh1	Idh3a	Idh3b	Idh3g	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
MP:0005374	lethality-prenatal/perinatal	4933405O20Rik	Aco1	Aco2	Cs	Csl	Fh1	Idh3a	Idh3b	Idh3g	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
MP:0003631	nervous system phenotype	4933405O20Rik	Aco1	Aco2	Cs	Csl	Fh1	Idh3a	Idh3b	Idh3g	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
MP:0002873	normal phenotype	4933405O20Rik	Aco1	Aco2	Cs	Csl	Fh1	Idh3a	Idh3b	Idh3g	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
MP:0005367	renal/urinary system phenotype	4933405O20Rik	Aco1	Aco2	Cs	Csl	Fh1	Idh3a	Idh3b	Idh3g	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2

Full set of annotations for TCA cycle variation III (eukaryotic)

ID	Term	Mouse gene	Alleles	Background	Color Key
MP:0003437	abnormal carotid body morphology	Sdhd	Sdhd^tm1Jlob/Sdhd⁺	involves: 129X1/SvJ	color key
MP:0003438	abnormal carotid body physiology	Sdhd	Sdhd^tm1Jlob/Sdhd⁺	involves: 129X1/SvJ	color key
MP:0005584	abnormal enzyme/coenzyme activity	Fh1	Fh1^tm1Pjp/Fh1^tm1Pjp,Tg(Cdh16-cre)91Igr/0	involves: 129X1/SvJ * ICR	color key
MP:0005584	abnormal enzyme/coenzyme activity	Mdh1	Mdh1^am1H/Mdh1⁺	involves: C3H/HeH	color key
MP:0005637	abnormal iron homeostasis	Aco1	Aco1^tm1Roua/Aco1^tm1Roua	involves: 129/Sv * C57BL/6	color key
MP:0006036	abnormal mitochondrial physiology	Sdhd	Sdhd^tm1Jlob/Sdhd⁺	involves: 129X1/SvJ	color key
MP:0002703	abnormal renal tubule morphology	Fh1	Fh1^tm1Pjp/Fh1^tm1Pjp,Tg(Cdh16-cre)91Igr/0	involves: 129X1/SvJ * ICR	color key
MP:0001730	embryonic growth arrest	Sdhd	Sdhd^tm1Jlob/Sdhd^tm1Jlob	involves: 129X1/SvJ	color key
MP:0006205	embryonic lethality before somite formation	Fh1	Fh1^tm1.1Pjp/Fh1^tm1.1Pjp	involves: 129X1/SvJ * BALB/c * C57BL/6	color key
MP:0006205	embryonic lethality before somite formation	Sdhd	Sdhd^tm1Jlob/Sdhd^tm1Jlob	involves: 129X1/SvJ	color key
MP:0005264	glomerulosclerosis	Fh1	Fh1^tm1Pjp/Fh1^tm1Pjp,Tg(Cdh16-cre)91Igr/0	involves: 129X1/SvJ * ICR	color key
MP:0000519	hydronephrosis	Fh1	Fh1^tm1Pjp/Fh1^tm1Pjp,Tg(Cdh16-cre)91Igr/0	involves: 129X1/SvJ * ICR	color key
MP:0000522	kidney cortex cysts	Fh1	Fh1^tm1Pjp/Fh1^tm1Pjp,Tg(Cdh16-cre)91Igr/0	involves: 129X1/SvJ * ICR	color key
MP:0003675	kidney cysts	Fh1	Fh1^tm1Pjp/Fh1^tm1Pjp,Tg(Cdh16-cre)91Igr/0	involves: 129X1/SvJ * ICR	color key
MP:0003606	kidney failure	Fh1	Fh1^tm1Pjp/Fh1^tm1Pjp,Tg(Cdh16-cre)91Igr/0	involves: 129X1/SvJ * ICR	color key
MP:0006208	lethality throughout fetal growth and development	Aco1	Aco1^tm1Mwh/Aco1^tm1Mwh	involves: 129P2/OlaHsd * C57BL/6J	color key
MP:0002169	no abnormal phenotype detected	Aco1	Aco1^tm1.1Mwh/Aco1^tm1.1Mwh	involves: 129P2/OlaHsd * C57BL/6 * SJL	color key
MP:0002169	no abnormal phenotype detected	Aco1	Aco1^tm1.2Mwh/Aco1^tm1.2Mwh	involves: 129P2/OlaHsd * C57BL/6J	color key
MP:0001762	polyuria	Fh1	Fh1^tm1Pjp/Fh1^tm1Pjp,Tg(Cdh16-cre)91Igr/0	involves: 129X1/SvJ * ICR	color key
MP:0002080	prenatal lethality	Mdh1	Mdh1^am1H/Mdh1^am1H	involves: C3H/HeH	color key