MGI MouseCyc MP annotations for PWY-5410

MGI MouseCyc experimental MP annotations for 13-LOX and 13-HPL pathway

Roles of genes might be detected in a summary/comparison table of high level MP categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";

Compare annotations to MP categories for 13-LOX and 13-HPL pathway

Entry indicates that gene is in this pathway.
Colored entries indicate MP annotation.

ID	Term	Alox5
MP:0005375	adipose tissue phenotype	Alox5
MP:0005385	cardiovascular system phenotype	Alox5
MP:0005397	hematopoietic system phenotype	Alox5
MP:0005376	homeostasis/metabolism phenotype	Alox5
MP:0005387	immune system phenotype	Alox5
MP:0005390	skeleton phenotype	Alox5

Full set of annotations for 13-LOX and 13-HPL pathway

ID	Term	Mouse gene	Alleles	Background	Color Key
MP:0001790	abnormal immune system physiology	Alox5	Alox5^tm1Fun/Alox5^tm1Fun	involves: 129S2/SvPas * C57BL/6	color key
MP:0001845	abnormal inflammatory response	Alox5	Alox5^tm1Bhk/Alox5^tm1Bhk	either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * C57BL/6 * DBA/2)	color key
MP:0002511	abnormal leukotriene C4 physiology	Alox5	Alox5^tm1Bhk/Alox5^tm1Bhk	either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * C57BL/6 * DBA/2)	color key
MP:0002516	abnormal PGE2 physiology	Alox5	Alox5^tm1Bhk/Alox5^tm1Bhk	either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * C57BL/6 * DBA/2)	color key
MP:0002510	abnormal leukotriene physiology	Alox5	Alox5^tm1Bhk/Alox5^tm1Bhk	either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * C57BL/6 * DBA/2)	color key
MP:0002463	abnormal neutrophil physiology	Alox5	Alox5^tm1Bhk/Alox5^tm1Bhk	either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * C57BL/6 * DBA/2)	color key
MP:0002519	abnormal thromboxane physiology	Alox5	Alox5^tm1Bhk/Alox5^tm1Bhk	either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * C57BL/6 * DBA/2)	color key
MP:0002502	abnormal vasoactive mediator physiology	Alox5	Alox5^tm1Bhk/Alox5^tm1Bhk	either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * C57BL/6 * DBA/2)	color key
MP:0005087	decreased acute inflammation	Alox5	Alox5^tm1Bhk/Alox5^tm1Bhk	either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * C57BL/6 * DBA/2)	color key
MP:0001876	decreased inflammatory response	Alox5	Alox5^tm1Fun/Alox5^tm1Fun	involves: 129S2/SvPas * C57BL/6	color key
MP:0005351	decreased susceptibility to autoimmune disorder	Alox5	Alox5^tm1Fun/Alox5^tm1Fun	B6.129S2-Alox5/J	color key
MP:0005597	decreased susceptibility to type I hypersensitivity reaction	Alox5	Alox5^tm1Bhk/Alox5^tm1Bhk	either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * C57BL/6 * DBA/2)	color key
MP:0008720	impaired neutrophil migration	Alox5	Alox5^tm1Bhk/Alox5^tm1Bhk	either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * C57BL/6 * DBA/2)	color key
MP:0008719	impaired neutrophil recruitment	Alox5	Alox5^tm1Bhk/Alox5^tm1Bhk	either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * C57BL/6 * DBA/2)	color key
MP:0000062	increased bone density	Alox5	Alox5^tm1Fun/Alox5^tm1Fun	B6.129S2-Alox5/J	color key
MP:0005669	increased circulating leptin level	Alox5	Alox5^tm1Fun/Alox5^tm1Fun	B6.129S2-Alox5/J	color key
MP:0005145	increased circulating VLDL cholesterol level	Alox5	Alox5^tm1Fun/Alox5^tm1Fun	B6.129S2-Alox5/J	color key
MP:0008908	increased total fat pad weight	Alox5	Alox5^tm1Fun/Alox5^tm1Fun	B6.129S2-Alox5/J	color key
MP:0000692	small spleen	Alox5	Alox5^tm1Fun/Alox5^tm1Fun	involves: 129S2/SvPas * C57BL/6	color key