MGI MouseCyc MP annotations for PWY-5046

MGI MouseCyc experimental MP annotations for branched-chain α-keto acid dehydrogenase complex

Roles of genes might be detected in a summary/comparison table of high level MP categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";

Compare annotations to MP categories for branched-chain α-keto acid dehydrogenase complex

Entry indicates that gene is in this pathway.
Colored entries indicate MP annotation.

ID	Term	Bckdha	Bckdhb	Dbt	Dld
MP:0005375	adipose tissue phenotype	Bckdha	Bckdhb	Dbt	Dld
MP:0005386	behavior/neurological phenotype	Bckdha	Bckdhb	Dbt	Dld
MP:0005380	embryogenesis phenotype	Bckdha	Bckdhb	Dbt	Dld
MP:0005378	growth/size phenotype	Bckdha	Bckdhb	Dbt	Dld
MP:0005376	homeostasis/metabolism phenotype	Bckdha	Bckdhb	Dbt	Dld
MP:0005373	lethality-postnatal	Bckdha	Bckdhb	Dbt	Dld
MP:0005374	lethality-prenatal/perinatal	Bckdha	Bckdhb	Dbt	Dld
MP:0005372	life span-post-weaning/aging	Bckdha	Bckdhb	Dbt	Dld
MP:0005370	liver/biliary system phenotype	Bckdha	Bckdhb	Dbt	Dld
MP:0005369	muscle phenotype	Bckdha	Bckdhb	Dbt	Dld
MP:0003631	nervous system phenotype	Bckdha	Bckdhb	Dbt	Dld
MP:0005367	renal/urinary system phenotype	Bckdha	Bckdhb	Dbt	Dld
MP:0005389	reproductive system phenotype	Bckdha	Bckdhb	Dbt	Dld
MP:0005388	respiratory system phenotype	Bckdha	Bckdhb	Dbt	Dld
MP:0005393	skin/coat/nails phenotype	Bckdha	Bckdhb	Dbt	Dld

Full set of annotations for branched-chain α-keto acid dehydrogenase complex

ID	Term	Mouse gene	Alleles	Background	Color Key
MP:0000003	abnormal adipose tissue morphology	Bckdha	Bckdha^{Gt(VICT48)710Lex}/Bckdha^{Gt(VICT48)710Lex}	B6.129S/SvEvBrd-Bckdha	color key
MP:0005332	abnormal amino acid level	Bckdha	Bckdha^{Gt(VICT48)710Lex}/Bckdha^{Gt(VICT48)710Lex}	B6.129S/SvEvBrd-Bckdha	color key
MP:0005332	abnormal amino acid level	Dbt	Dbt^tm1Geh/Dbt^tm1Geh	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	color key
MP:0003860	abnormal carbon dioxide level	Bckdha	Bckdha^{Gt(VICT48)710Lex}/Bckdha^{Gt(VICT48)710Lex}	B6.129S/SvEvBrd-Bckdha	color key
MP:0005311	abnormal circulating amino acid level	Bckdha	Bckdha^{Gt(VICT48)710Lex}/Bckdha^{Gt(VICT48)710Lex}	B6.129S/SvEvBrd-Bckdha	color key
MP:0005311	abnormal circulating amino acid level	Dbt	Dbt^tm1Geh/Dbt^tm1Geh,Tg(tetO-DBT)525AGeh/0,Tg(tTALap)5Bjd/0	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB * NMRI	color key
MP:0005311	abnormal circulating amino acid level	Dbt	Dbt^tm1Geh/Dbt^tm1Geh	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	color key
MP:0005311	abnormal circulating amino acid level	Dbt	Dbt^tm1Geh/Dbt^tm1Geh,Tg(tetO-DBT)A1Geh/0,Tg(tTALap)5Bjd/0	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB * NMRI	color key
MP:0001510	abnormal coat appearance	Bckdha	Bckdha^{Gt(VICT48)710Lex}/Bckdha^{Gt(VICT48)710Lex}	B6.129S/SvEvBrd-Bckdha	color key
MP:0001685	abnormal endoderm development	Dld	Dld^tm1Ptl/Dld^tm1Ptl	involves: 129P2/OlaHsd * Black Swiss	color key
MP:0005584	abnormal enzyme/coenzyme activity	Dbt	Dbt^tm1Geh/Dbt^tm1Geh,Tg(tetO-DBT)525AGeh/0,Tg(tTALap)5Bjd/0	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB * NMRI	color key
MP:0005584	abnormal enzyme/coenzyme activity	Dbt	Dbt^tm1Geh/Dbt^tm1Geh,Tg(tetO-DBT)A1Geh/0,Tg(tTALap)5Bjd/0	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB * NMRI	color key
MP:0001406	abnormal gait	Bckdha	Bckdha^{Gt(VICT48)710Lex}/Bckdha^{Gt(VICT48)710Lex}	B6.129S/SvEvBrd-Bckdha	color key
MP:0001961	abnormal reflex	Bckdha	Bckdha^{Gt(VICT48)710Lex}/Bckdha^{Gt(VICT48)710Lex}	B6.129S/SvEvBrd-Bckdha	color key
MP:0003311	aminoaciduria	Dbt	Dbt^tm1Geh/Dbt^tm1Geh	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	color key
MP:0001265	decreased body size	Bckdha	Bckdha^{Gt(VICT48)710Lex}/Bckdha^{Gt(VICT48)710Lex}	B6.129S/SvEvBrd-Bckdha	color key
MP:0001262	decreased body weight	Bckdha	Bckdha^{Gt(VICT48)710Lex}/Bckdha^{Gt(VICT48)710Lex}	B6.129S/SvEvBrd-Bckdha	color key
MP:0002175	decreased brain weight	Bckdha	Bckdha^{Gt(VICT48)710Lex}/Bckdha^{Gt(VICT48)710Lex}	B6.129S/SvEvBrd-Bckdha	color key
MP:0004232	decreased muscle weight	Bckdha	Bckdha^{Gt(VICT48)710Lex}/Bckdha^{Gt(VICT48)710Lex}	B6.129S/SvEvBrd-Bckdha	color key
MP:0001730	embryonic growth arrest	Dld	Dld^tm1Ptl/Dld^tm1Ptl	involves: 129P2/OlaHsd * Black Swiss	color key
MP:0003984	embryonic growth retardation	Dld	Dld^tm1Ptl/Dld^tm1Ptl	involves: 129P2/OlaHsd * Black Swiss	color key
MP:0006206	embryonic lethality before turning of embryo	Dld	Dld^tm1Ptl/Dld^tm1Ptl	involves: 129P2/OlaHsd * Black Swiss	color key
MP:0003917	increased kidney weight	Bckdha	Bckdha^{Gt(VICT48)710Lex}/Bckdha^{Gt(VICT48)710Lex}	B6.129S/SvEvBrd-Bckdha	color key
MP:0002981	increased liver weight	Bckdha	Bckdha^{Gt(VICT48)710Lex}/Bckdha^{Gt(VICT48)710Lex}	B6.129S/SvEvBrd-Bckdha	color key
MP:0008569	lethality at weaning	Bckdha	Bckdha^{Gt(VICT48)710Lex}/Bckdha^{Gt(VICT48)710Lex}	B6.129S/SvEvBrd-Bckdha	color key
MP:0005202	lethargy	Dbt	Dbt^tm1Geh/Dbt^tm1Geh	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	color key
MP:0003717	pallor	Dbt	Dbt^tm1Geh/Dbt^tm1Geh	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	color key
MP:0001732	postnatal growth retardation	Bckdha	Bckdha^{Gt(VICT48)710Lex}/Bckdha^{Gt(VICT48)710Lex}	B6.129S/SvEvBrd-Bckdha	color key
MP:0002082	postnatal lethality	Dbt	Dbt^tm1Geh/Dbt^tm1Geh,Tg(tetO-DBT)525AGeh/0,Tg(tTALap)5Bjd/0	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB * NMRI	color key
MP:0002082	postnatal lethality	Dbt	Dbt^tm1Geh/Dbt^tm1Geh	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	color key
MP:0002082	postnatal lethality	Dbt	Dbt^tm1Geh/Dbt^tm1Geh,Tg(tetO-DBT)A1Geh/0,Tg(tTALap)5Bjd/0	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB * NMRI	color key
MP:0002083	premature death	Bckdha	Bckdha^{Gt(VICT48)710Lex}/Bckdha^{Gt(VICT48)710Lex}	B6.129S/SvEvBrd-Bckdha	color key
MP:0002083	premature death	Dbt	Dbt^tm1Geh/Dbt^tm1Geh,Tg(tetO-DBT)525AGeh/0,Tg(tTALap)5Bjd/0	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB * NMRI	color key
MP:0002083	premature death	Dbt	Dbt^tm1Geh/Dbt^tm1Geh,Tg(tetO-DBT)A1Geh/0,Tg(tTALap)5Bjd/0	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB * NMRI	color key
MP:0001698	reduced embryo size	Dld	Dld^tm1Ptl/Dld^tm1Ptl	involves: 129P2/OlaHsd * Black Swiss	color key
MP:0001921	reduced fertility	Bckdha	Bckdha^{Gt(VICT48)710Lex}/Bckdha^{Gt(VICT48)710Lex}	B6.129S/SvEvBrd-Bckdha	color key
MP:0001954	respiratory distress	Dbt	Dbt^tm1Geh/Dbt^tm1Geh	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	color key
MP:0002064	seizures	Bckdha	Bckdha^{Gt(VICT48)710Lex}/Bckdha^{Gt(VICT48)710Lex}	B6.129S/SvEvBrd-Bckdha	color key
MP:0003997	tonic-clonic seizures	Bckdha	Bckdha^{Gt(VICT48)710Lex}/Bckdha^{Gt(VICT48)710Lex}	B6.129S/SvEvBrd-Bckdha	color key