MGI MouseCyc experimental GO annotations for PWY-5910

MGI MouseCyc experimental GO annotations for PWY-5910: superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate)

Roles of genes might be detected in a summary/comparison table of high level GO categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";
Black arrows indicate "regulates";
Green arrows indicate "positively_regulates";
Red arrows indicate "negatively_regulates"

Compare annotations to GO categories for PWY-5910: superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate)

Entry indicates that gene is in this pathway.
Colored entries indicate GO annotation.

Category	ID	Term	Acat1	Acat2	Fdps	Fntb	Ggps1	Hmgcr	Hmgcs1	Hmgcs2	Idi1	Idi2	Mvd	Mvk	Nudt12	Pmvk
Molecular Function	GO:0003824	catalytic activity	Acat1	Acat2	Fdps	Fntb	Ggps1	Hmgcr	Hmgcs1	Hmgcs2	Idi1	Idi2	Mvd	Mvk	Nudt12	Pmvk
Cellular Component	GO:0005623	cell	Acat1	Acat2	Fdps	Fntb	Ggps1	Hmgcr	Hmgcs1	Hmgcs2	Idi1	Idi2	Mvd	Mvk	Nudt12	Pmvk
Cellular Component	GO:0044464	cell part	Acat1	Acat2	Fdps	Fntb	Ggps1	Hmgcr	Hmgcs1	Hmgcs2	Idi1	Idi2	Mvd	Mvk	Nudt12	Pmvk
Cellular Component	GO:0031975	envelope	Acat1	Acat2	Fdps	Fntb	Ggps1	Hmgcr	Hmgcs1	Hmgcs2	Idi1	Idi2	Mvd	Mvk	Nudt12	Pmvk
Cellular Component	GO:0043226	organelle	Acat1	Acat2	Fdps	Fntb	Ggps1	Hmgcr	Hmgcs1	Hmgcs2	Idi1	Idi2	Mvd	Mvk	Nudt12	Pmvk
Cellular Component	GO:0044422	organelle part	Acat1	Acat2	Fdps	Fntb	Ggps1	Hmgcr	Hmgcs1	Hmgcs2	Idi1	Idi2	Mvd	Mvk	Nudt12	Pmvk
Biological Process	GO:0065007	biological regulation	Acat1	Acat2	Fdps	Fntb	Ggps1	Hmgcr	Hmgcs1	Hmgcs2	Idi1	Idi2	Mvd	Mvk	Nudt12	Pmvk
Biological Process	GO:0009987	cellular process	Acat1	Acat2	Fdps	Fntb	Ggps1	Hmgcr	Hmgcs1	Hmgcs2	Idi1	Idi2	Mvd	Mvk	Nudt12	Pmvk
Biological Process	GO:0032502	developmental process	Acat1	Acat2	Fdps	Fntb	Ggps1	Hmgcr	Hmgcs1	Hmgcs2	Idi1	Idi2	Mvd	Mvk	Nudt12	Pmvk
Biological Process	GO:0008152	metabolic process	Acat1	Acat2	Fdps	Fntb	Ggps1	Hmgcr	Hmgcs1	Hmgcs2	Idi1	Idi2	Mvd	Mvk	Nudt12	Pmvk
Biological Process	GO:0032501	multicellular organismal process	Acat1	Acat2	Fdps	Fntb	Ggps1	Hmgcr	Hmgcs1	Hmgcs2	Idi1	Idi2	Mvd	Mvk	Nudt12	Pmvk
Biological Process	GO:0048519	negative regulation of biological process	Acat1	Acat2	Fdps	Fntb	Ggps1	Hmgcr	Hmgcs1	Hmgcs2	Idi1	Idi2	Mvd	Mvk	Nudt12	Pmvk
Biological Process	GO:0048518	positive regulation of biological process	Acat1	Acat2	Fdps	Fntb	Ggps1	Hmgcr	Hmgcs1	Hmgcs2	Idi1	Idi2	Mvd	Mvk	Nudt12	Pmvk
Biological Process	GO:0050789	regulation of biological process	Acat1	Acat2	Fdps	Fntb	Ggps1	Hmgcr	Hmgcs1	Hmgcs2	Idi1	Idi2	Mvd	Mvk	Nudt12	Pmvk
Biological Process	GO:0050896	response to stimulus	Acat1	Acat2	Fdps	Fntb	Ggps1	Hmgcr	Hmgcs1	Hmgcs2	Idi1	Idi2	Mvd	Mvk	Nudt12	Pmvk

Full set of annotations for PWY-5910: superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate)

Category	ID	Term	Mouse gene	Evidence	Color Key
Molecular Function	GO:0003985	acetyl-CoA C-acetyltransferase activity	Acat1	IDA	color key
Molecular Function	GO:0004311	farnesyltranstransferase activity	Fntb	IMP	color key
Molecular Function	GO:0004337	geranyltranstransferase activity	Ggps1	IDA	color key
Molecular Function	GO:0004420	hydroxymethylglutaryl-CoA reductase (NADPH) activity	Hmgcr	IDA	color key
Molecular Function	GO:0004496	mevalonate kinase activity	Mvk	IDA	color key
Molecular Function	GO:0004631	phosphomevalonate kinase activity	Pmvk	IDA	color key
Cellular Component	GO:0005792	microsome	Hmgcr	IDA	color key
Cellular Component	GO:0005743	mitochondrial inner membrane	Acat1	IDA	color key
Cellular Component	GO:0005743	mitochondrial inner membrane	Hmgcs2	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Acat1	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Hmgcs2	IDA	color key
Biological Process	GO:0006695	cholesterol biosynthetic process	Hmgcr	IDA	color key
Biological Process	GO:0009790	embryonic development	Hmgcr	IMP	color key
Biological Process	GO:0008285	negative regulation of cell proliferation	Fntb	IMP	color key
Biological Process	GO:0043407	negative regulation of MAP kinase activity	Hmgcr	IGI	color key
Biological Process	GO:0008284	positive regulation of cell proliferation	Fntb	IMP	color key
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	Fntb	IMP	color key
Biological Process	GO:0008542	visual learning	Hmgcr	IGI	color key
Biological Process	GO:0042060	wound healing	Fntb	IMP	color key