| Term: | G2/M transition of mitotic cell cycle |
|---|---|
| Synonyms: | mitotic G2/M transition |
| Definition: | The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex. |
| Parent Terms: |
is-a
cell cycle G2/M phase transition is-a mitotic cell cycle phase transition |
| Category: | Biological Process |
| ID: | GO:0000086 |