GO Annotations Graph

• Symbol: Nr4a3
• Name: nuclear receptor subfamily 4, group A, member 3
• ID: MGI:1352457

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0035497	cAMP response element binding	IDA	J:205020
Molecular Function	GO:0003677	DNA binding	ISO	J:155856
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:177579
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:155856
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:165911
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:165911
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:40025
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IEA	J:72247
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0035035	histone acetyltransferase binding	IPI	J:222684
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0035259	nuclear glucocorticoid receptor binding	ISO	J:155856
Molecular Function	GO:0035259	nuclear glucocorticoid receptor binding	IBA	J:265628
Molecular Function	GO:0004879	nuclear receptor activity	IEA	J:72247
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:155856
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:177579
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:37081
Molecular Function	GO:0001223	transcription coactivator binding	IPI	J:222684
Molecular Function	GO:0001223	transcription coactivator binding	IPI	J:222684
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005667	transcription regulator complex	IBA	J:265628
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:40025
Biological Process	GO:0030534	adult behavior	IMP	J:73971
Biological Process	GO:0007411	axon guidance	IMP	J:93320
Biological Process	GO:0007049	cell cycle	IMP	J:165911
Biological Process	GO:0045333	cellular respiration	IMP	J:222682
Biological Process	GO:0071870	cellular response to catecholamine stimulus	IDA	J:222682
Biological Process	GO:0071376	cellular response to corticotropin-releasing hormone stimulus	IDA	J:222687
Biological Process	GO:0071376	cellular response to corticotropin-releasing hormone stimulus	IBA	J:265628
Biological Process	GO:0044320	cellular response to leptin stimulus	IDA	J:151527
Biological Process	GO:0035726	common myeloid progenitor cell proliferation	IMP	J:216777
Biological Process	GO:0097048	dendritic cell apoptotic process	IMP	J:147174
Biological Process	GO:0006351	DNA-templated transcription	IDA	J:165911
Biological Process	GO:0097009	energy homeostasis	IMP	J:151527
Biological Process	GO:0097009	energy homeostasis	IMP	J:205020
Biological Process	GO:0045444	fat cell differentiation	IDA	J:222681
Biological Process	GO:0007369	gastrulation	IMP	J:89944
Biological Process	GO:0021766	hippocampus development	IMP	J:93320
Biological Process	GO:0042472	inner ear morphogenesis	IMP	J:73971
Biological Process	GO:0043303	mast cell degranulation	IMP	J:213833
Biological Process	GO:0001707	mesoderm formation	IMP	J:89944
Biological Process	GO:1903208	negative regulation of hydrogen peroxide-induced neuron death	IMP	J:162076
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IMP	J:93320
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IMP	J:162076
Biological Process	GO:1903204	negative regulation of oxidative stress-induced neuron death	IGI	J:162076
Biological Process	GO:0034392	negative regulation of smooth muscle cell apoptotic process	IMP	J:165911
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:205020
Biological Process	GO:0050885	neuromuscular process controlling balance	IMP	J:73971
Biological Process	GO:0051402	neuron apoptotic process	IMP	J:93320
Biological Process	GO:0051402	neuron apoptotic process	IMP	J:162076
Biological Process	GO:0048008	platelet-derived growth factor receptor signaling pathway	ISO	J:164563
Biological Process	GO:0010613	positive regulation of cardiac muscle hypertrophy	ISO	J:155856
Biological Process	GO:0045787	positive regulation of cell cycle	IMP	J:165911
Biological Process	GO:2000670	positive regulation of dendritic cell apoptotic process	IMP	J:147174
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:222684
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	IMP	J:73971
Biological Process	GO:0046321	positive regulation of fatty acid oxidation	IMP	J:222682
Biological Process	GO:2000253	positive regulation of feeding behavior	IMP	J:151527
Biological Process	GO:0010828	positive regulation of glucose transmembrane transport	ISO	J:164563
Biological Process	GO:0038097	positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway	IMP	J:213833
Biological Process	GO:0032765	positive regulation of mast cell cytokine production	IMP	J:213833
Biological Process	GO:1900625	positive regulation of monocyte aggregation	ISO	J:164563
Biological Process	GO:1900625	positive regulation of monocyte aggregation	IMP	J:175040
Biological Process	GO:0048661	positive regulation of smooth muscle cell proliferation	IMP	J:178133
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:177579
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:91558
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:91558
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:40025
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:37081
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:165911
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:165911
Biological Process	GO:1904754	positive regulation of vascular associated smooth muscle cell migration	ISO	J:164563
Biological Process	GO:1904707	positive regulation of vascular associated smooth muscle cell proliferation	ISO	J:164563
Biological Process	GO:0009444	pyruvate oxidation	IMP	J:222682
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0048660	regulation of smooth muscle cell proliferation	ISO	J:164563
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0061469	regulation of type B pancreatic cell proliferation	ISO	J:155856
Biological Process	GO:0042542	response to hydrogen peroxide	IMP	J:162076
Biological Process	GO:0048752	semicircular canal morphogenesis	IMP	J:73971
Biological Process	GO:0034390	smooth muscle cell apoptotic process	IMP	J:165911
Biological Process	GO:0060005	vestibular reflex	IMP	J:73971