Exoc1l Gene Detail

Summary

• Symbol
  Exoc1l
• Name
  exocyst complex component 1 like
• Synonyms
  Gm7271

• Feature Type
  protein coding gene
  BioType Conflict
  
• IDs
  MGI:3647743
  NCBI Gene: 639545
• Alliance
  genome feature page

Location &
Maps

• Sequence Map
  Chr5:76631924-76664475 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 5, 41.23 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  791 from dbSNP Build 142
• Strain Annotations
  19

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3647743	protein coding gene	Chr5:76631887-76664496 (+)
129S1/SvImJ	ENSMUSG00200000715	protein coding gene	Chr5:72322071-72354677 (+)
A/J	ENSMUSG00195010018	protein coding gene	Chr5:71636911-71669741 (+)
AKR/J	ENSMUSG00220014471	protein coding gene	Chr5:71748641-71781478 (+)
BALB/cJ	ENSMUSG00180020511	protein coding gene	Chr5:71393821-71426428 (+)
C3H/HeJ	ENSMUSG00175004096	protein coding gene	Chr5:73437748-73470372 (+)
C57BL/6NJ	ENSMUSG00215000423	protein coding gene	Chr5:72208392-72241004 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0006071	lincRNA gene	Chr5:69386573-69412244 (+)
CAST/EiJ	ENSTCUG00005013337	protein coding gene	Chr5:71185464-71219136 (+)
CBA/J	ENSMUSG00210000501	protein coding gene	Chr5:72375688-72408312 (+)
DBA/2J	ENSMUSG00185015327	protein coding gene	Chr5:74205643-74238267 (+)
FVB/NJ	ENSMUSG00205023017	protein coding gene	Chr5:71164136-71196973 (+)
JF1/MsJ	ENSUMUG00000005350	protein coding gene	Chr5:78681138-78714809 (+)
LP/J	ENSMUSG00230017732	protein coding gene	Chr5:78896055-78928664 (+)
NOD/ShiLtJ	ENSMUSG00190007664	protein coding gene	Chr5:71326146-71358785 (+)
NZO/HlLtJ	ENSMUSG00225033548	protein coding gene	Chr5:83943046-83975655 (+)
PWK/PhJ	ENSLUMG00010007390	protein coding gene	Chr5:71273887-71307543 (+)
SPRET/EiJ	ENSMSPG00010009394	protein coding gene	Chr5:73265662-73292146 (+)
WSB/EiJ	ENSIUOG00005018277	protein coding gene	Chr5:74171522-74205908 (+)

Homology

• Human Ortholog
  EXOC1L, exocyst complex component 1 like

• Vertebrate Orthologs
  3

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  EXOC1L, exocyst complex component 1 like
  
• Links
  HGNC:53433

  NCBI Gene ID: 644145

  UniProt: A0A1B0GW35

  
  
• Chr Location
  4q12; chr4:55819790-55837489 (+)  GRCh38

---

• MGI Vertebrate Homology
  Exoc1l stringent orthology
  1 human;1 mouse;1 rat;1 zebrafish
  
• HCOP
  vertebrate homology predictions: EXOC1L
• Gene Tree
  Exoc1l
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  5 phenotype references
  

• All Mutations and Alleles
  5
• Chemically induced (other)
  2
• Endonuclease-mediated
  1
• Spontaneous
  2
• Genomic Mutations
  5 involving Exoc1l
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  5 strains or lines available

Expression

• Assay Results
  597

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas
• Other Vertebrate Links
  ZFIN exoc1l

Sequences &
Gene Models

• All Sequences
  28
• RefSeq
  1
• UniProt
  1

• Ensembl
  ENSMUSG00000091204 (Evidence)
• NCBI Gene
  639545

Representative Sequences			Length	Strain/Species
genomic	639545	NCBI Gene Model | MGI Sequence Detail	32552	C57BL/6J
transcript	NR_033501	RefSeq | MGI Sequence Detail	817	C57BL/6
polypeptide	B9EK06	UniProt | EBI | MGI Sequence Detail	172	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• Protein Ontology
  PR:000059668 exocyst complex component 1-like
  (term hierarchy)
• InterPro Domains
  IPR028258 Exocyst complex component Sec3, PIP2-binding N-terminal domain

Other
Accession IDs

MGI:6762182

References

• Summaries
  All 12

  Phenotypes 5
• Earliest
  J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
• Latest
  J:233978 Mizuno S, et al., Peri-implantation lethality in mice carrying megabase-scale deletion on 5qc3.3 is caused by Exoc1 null mutation. Sci Rep. 2015;5:13632