Exoc1l Gene Detail

Summary

• Symbol
  Exoc1l
• Name
  exocyst complex component 1 like
• Synonyms
  Gm7271

• Feature Type
  protein coding gene
  BioType Conflict
  
• IDs
  MGI:3647743
  NCBI Gene: 639545
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Chr5:76631924-76664475 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 5, 41.23 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  90 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3647743	protein coding gene	Chr5:76631887-76664496 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0006678	lincRNA gene	Chr5:76672687-76701324 (+)
A/J	MGP_AJ_G0006672	lincRNA gene	Chr5:73754684-73784284 (+)
AKR/J	MGP_AKRJ_G0006642	lincRNA gene	Chr5:76157081-76183177 (+)
BALB/cJ	MGP_BALBcJ_G0006647	lincRNA gene	Chr5:74484891-74514578 (+)
C3H/HeJ	MGP_C3HHeJ_G0006593	lincRNA gene	Chr5:76526818-76556240 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0006812	lincRNA gene	Chr5:79738419-79767867 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0006071	lincRNA gene	Chr5:69386573-69412244 (+)
CAST/EiJ	MGP_CASTEiJ_G0006516	lincRNA gene	Chr5:75719096-75760188 (+)
CBA/J	MGP_CBAJ_G0006574	lincRNA gene	Chr5:82351765-82388697 (+)
DBA/2J	MGP_DBA2J_G0006594	lincRNA gene	Chr5:73812078-73841466 (+)
FVB/NJ	MGP_FVBNJ_G0006619	lincRNA gene	Chr5:73003377-73037691 (+)
LP/J	MGP_LPJ_G0006679	lincRNA gene	Chr5:77111473-77143813 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0006603	lincRNA gene	Chr5:85528028-85561009 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0006814	lincRNA gene	Chr5:75696881-75731233 (+)
PWK/PhJ	MGP_PWKPhJ_G0006455	lincRNA gene	Chr5:72824235-72858704 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0006362	lincRNA gene	Chr5:75063162-75093422 (+)
WSB/EiJ	MGP_WSBEiJ_G0006567	lincRNA gene	Chr5:76018655-76057431 (+)

Homology

• Human Ortholog
  EXOC1L, exocyst complex component 1 like

• Vertebrate Orthologs
  3

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  EXOC1L, exocyst complex component 1 like
  
• Links
  HGNC:53433

  NCBI Gene ID: 644145

  UniProt: A0A1B0GW35

  
  
• Chr Location
  4q12; chr4:55819790-55837489 (+)  GRCh38

---

• MGI Vertebrate Homology
  Exoc1l stringent orthology
  1 human;1 mouse;1 rat;1 zebrafish
  
• HCOP
  vertebrate homology predictions: EXOC1L
• Gene Tree
  Exoc1l
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  5 phenotype references
  

• All Mutations and Alleles
  5
• Chemically induced (other)
  2
• Endonuclease-mediated
  1
• Spontaneous
  2
• Genomic Mutations
  5 involving Exoc1l
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  5 strains or lines available

Expression

• Assay Results
  706

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas
• Other Vertebrate Links
  ZFIN exoc1l

Sequences &
Gene Models

• All Sequences
  27
• RefSeq
  1
• UniProt
  1

• Ensembl
  ENSMUSG00000091204 (Evidence)
• NCBI Gene
  639545

Representative Sequences			Length	Strain/Species
genomic	639545	NCBI Gene Model | MGI Sequence Detail	32552	C57BL/6J
transcript	NR_033501	RefSeq | MGI Sequence Detail	817	C57BL/6
polypeptide	B9EK06	UniProt | EBI | MGI Sequence Detail	172	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• Protein Ontology
  PR:000059668 exocyst complex component 1-like
  (term hierarchy)
• InterPro Domains
  IPR028258 Exocyst complex component Sec3, PIP2-binding N-terminal domain

References

• Summaries
  All 11

  Phenotypes 5
• Earliest
  J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
• Latest
  J:233978 Mizuno S, et al., Peri-implantation lethality in mice carrying megabase-scale deletion on 5qc3.3 is caused by Exoc1 null mutation. Sci Rep. 2015;5:13632